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BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition
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作者 Yu Meng Hui-Yan Sun +7 位作者 Yi He Qian Zhou Yi-Huang Liu Hui Su ming-zhu yin Fu-Rong Zeng Xiang Chen Guang-Tong Deng 《Military Medical Research》 SCIE CAS CSCD 2024年第4期620-624,共5页
Dear Editor,Ferroptosis,an iron-dependent form of cell death driven by overwhelming lipid peroxidation,represents a vulnerability in cancers,and therapeutic strategies to further potentiate ferroptosis hold great pote... Dear Editor,Ferroptosis,an iron-dependent form of cell death driven by overwhelming lipid peroxidation,represents a vulnerability in cancers,and therapeutic strategies to further potentiate ferroptosis hold great potential for melanoma treatment. 展开更多
关键词 MELANOMA Bromodomain and extra terminal domain(BET)inhibitor Ferroptosis Cell death AKR1C2 IMMUNOTHERAPY
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High-value utilization of CO_(2) to synthesize sulfur-doped carbon nanofibers with excellent capacitive performance 被引量:2
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作者 Meng-jun Hu ming-zhu yin +3 位作者 Li-wen Hu Peng-jie Liu Shuo Wang Jian-bang Ge 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2020年第12期1666-1677,共12页
Carbon nanofiber(CNF)is considered a promising material due to its excellent physical and chemical properties.This paper proposes a novel way to transform CO_(2) into heteroatom-doped CNFs,with the introduction of Fe,... Carbon nanofiber(CNF)is considered a promising material due to its excellent physical and chemical properties.This paper proposes a novel way to transform CO_(2) into heteroatom-doped CNFs,with the introduction of Fe,Co,and Ni as catalysts.When the electrolyte containing Ni O,Co2O3,and Fe_(2)O_(3) was employed,sulfur-doped CNFs in various diameters were obtained.With the introduction of Fe catalyst,the obtained sulfur-doped CNFs showed the smallest and tightest diameter distributions.The obtained sulfur-doped CNFs had high gravimetric capacitance(achieved by SDG-Fe)that could reach 348.5 F/g at 0.5 A/g,excellent cycling stability,and good rate performance.For comparison purposes,both Fe and nickel cathodes were tested,where the active metal atom at their surface could act as catalyst.In these two situations,sulfur-doped graphite sheet and sulfur-doped graphite quasi-sphere were the main products. 展开更多
关键词 carbon dioxide capture electrochemical conversion carbon fiber molten salt
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