The transmission line tower will be affected by bad weather and artificial subsidence caused by the foundation and other factors in the power transmission.The tower’s tilt and severe deformation will cause the buildi...The transmission line tower will be affected by bad weather and artificial subsidence caused by the foundation and other factors in the power transmission.The tower’s tilt and severe deformation will cause the building to collapse.Many small changes caused the tower’s collapse,but the early staff often could not intuitively notice the changes in the tower’s state.In the current tower online monitoring system,terminal equipment often needs to replace batteries frequently due to premature exhaustion of power.According to the need for real-time measurement of power line tower,this research designed a real-time monitoring device monitoring the transmission tower attitude tilting and foundation state based on the inertial sensor,the acceleration of 3 axis inertial sensor and angular velocity raw data to pole average filtering pre-processing,and then through the complementary filtering algorithm for comprehensive calculation of tilt angle,the system meets the demand for inclined online monitoring of power line poles and towers regarding measurement accuracy,with low cost and power consumption.The optimization multi-sensor cooperative detection and correction measured tilt angle result relative accuracy can reach 1.03%,which has specific promotion and application value since the system has the advantages of unattended and efficient calculation.展开更多
Previous studies at home and abroad have mainly focused on single dam-break, and little attention has been paid so far to the dam-break of cascade reservoirs.Multi-source flooding, which can lead to three-dimensional ...Previous studies at home and abroad have mainly focused on single dam-break, and little attention has been paid so far to the dam-break of cascade reservoirs.Multi-source flooding, which can lead to three-dimensional turbulent phenomena and superposition effects, is the main difference between the dam-break of cascade and single reservoirs. Detailed descriptions of the coupled numerical simulation of multi-source flooding have little been reported, and the initial wet riverbed is rarely considered in current models. Therefore, in this paper, a method based on the three-dimensional k-ε turbulence model coupled with the volume-of-fluid method is proposed to simulate the dam-break flooding of cascade reservoirs. The upstream river, reservoir, and downstream river are connected by the internal boundary method, and the initial conditions,including river flow and reservoir water, are determined according to the results of the numerical simulation. Coupled numerical simulation of different dam-break flooding is then achieved. The present work solves the challenges presented by the enhancement and superposition of natural river flow, upstream flooding, and downstream flooding.This paper provides a theoretical basis for future studies on the dam-break flood routing of cascade reservoirs.展开更多
Channel engineering stability with underground goafs is a complex three-dimensional problem, especially when considering channel leakage, and is influenced by a number of processes, such as seepage, fluid structure in...Channel engineering stability with underground goafs is a complex three-dimensional problem, especially when considering channel leakage, and is influenced by a number of processes, such as seepage, fluid structure interaction(FSI), modeling, and selection of geological mechanical parameters. In this study, stability finite element analysis by one-way FSI was performed by establishing an integrated 3D engineering geological model. The extended Fourier amplitude sensitivity test was used to quantitatively assess the first-order and total sensitivities of the engineering model to critical geological mechanical parameters. Results illustrate that the channel engineering deformation is under a reasonable range and the elastic modulus is the highest total sensitivity parameter for the channel tilt and curvature at 0.7395 and 0.7525, respectively. Moreover, the most observable coupling effects for the curvature and horizontal strain are cohesion(0.1933)and density(0.7410), respectively.展开更多
Understanding the assembly and spatial arrangement of bamboo cell wall components is crucial for its optimal utilization.Bamboo cell walls consist of aggregates of cellulose microfibrils and matrix.In the present stud...Understanding the assembly and spatial arrangement of bamboo cell wall components is crucial for its optimal utilization.Bamboo cell walls consist of aggregates of cellulose microfibrils and matrix.In the present study,the size and arrangement of cellulose microfibril aggregates in the cell walls of sclerenchyma fibers and parenchyma cells in moso bamboo were investigated with NMR and FE-SEM.The NMR measurement showed that the characteristic sizes of the microfibril aggregates of fibers and parenchyma cells were approximately 25.8 nm and 18.8 nm,respectively.Furthermore,high-resolution SEM showed the size of microfibril aggregates varied little across the cell wall of sclerenchyma fiber.However,there were significant size differences between the broad and narrow lamellae both in fiber and parenchyma cells,which is thought to be closely related to the orientation of microfibrils in these layers.The microfibril aggregates in the fibers mainly appear in a random arrangement,although occasionally in a radial or tangential arrangement in individual cell.Parenchyma cells have a relatively thinner cell wall layers,in which microfibril aggregates appear in a concentric lamellar arrangement.展开更多
The concept of optimal Delaunay triangulation (ODT) and the corresponding error-based quality metric are first introduced. Then one kind of mesh smoothing algorithm for tetrahedral mesh based on the concept of ODT is ...The concept of optimal Delaunay triangulation (ODT) and the corresponding error-based quality metric are first introduced. Then one kind of mesh smoothing algorithm for tetrahedral mesh based on the concept of ODT is examined. With regard to its problem of possible producing illegal elements, this paper proposes a modified smoothing scheme with a constrained optimization model for tetrahedral mesh quality improvement. The constrained optimization model is converted to an unconstrained one and then solved by integrating chaos search and BFGS (Broyden-Fletcher-Goldfarb-Shanno) algorithm efficiently. Quality improvement for tetrahedral mesh is finally achieved by alternately applying the presented smoothing scheme and re-triangulation. Some testing examples are given to demonstrate the effectiveness of the proposed approach.展开更多
Operating Room is an important place for surgical diagnosis and treatment and rescue of patients. With the rapid development of medical technology, high, precision, sharp continuous development, operating room safety ...Operating Room is an important place for surgical diagnosis and treatment and rescue of patients. With the rapid development of medical technology, high, precision, sharp continuous development, operating room safety management is particularly important. The error of the counting of the surgical articles causes the foreign body left in the patient’s body, which will cause irreversible damage to the patient and even cause the medical dispute and touch the legal problem. Operation items inventory system is an important working system in the operating room. Scientific and standardized methods and systems for counting surgical instruments and dressings during operation can prevent foreign bodies from being left in the body, prevent errors and accidents in the operating room, and are very important for ensuring the safety of the operation of patients. In order to ensure the safety of patients, it is necessary to ensure the correct inventory of surgical items. The factors affecting the accuracy of item counting in the operating room and the preventive measures are summarized as follows.展开更多
We present a study of the measurement of the effective weak mixing angle parameter(sin^(2)θ^(l)_(eff))at the Circular Electron Positron Collider(CEPC).As a fundamental physics parameter,sin^(2)θ_(eff)^(l) plays a ke...We present a study of the measurement of the effective weak mixing angle parameter(sin^(2)θ^(l)_(eff))at the Circular Electron Positron Collider(CEPC).As a fundamental physics parameter,sin^(2)θ_(eff)^(l) plays a key role not only in the global test of the standard model electroweak sector,but also in constraining the potential beyond standard model new physics at the high energy frontier.CEPC proposes a two year running period around the Z boson mass pole at high instataneous luminosity,providing a large data sample with 4 × 10^(12)Z candidates generated in total.It allows a high precision measurement of sin^(2)θ^(l)_(eff) both in the lepton and quark final states,where the uncertainty can be one order of magnitude lower than any previous measurement at the LEP,SLC,Tevatron,and LHC.It will improve the overall precision of the sin^(2)θ^(l)_(eff) experimental determination to be comparable to the preicision of the theoretical calculation with two-loop radiative corrections,and it will also provide direct comparisons between different final states.In this paper,we also study the measurement of sin^(2)θ^(l)_(eff) in the high mass region.Taking data for one month,the precision of sin^(2)θ^(l)_(eff) measured at 130 GeV from b quark final state is 0.00010,which will be an important experimental observation on the energy-running effect of sin^(2)θ^(l)_(eff).展开更多
A standard operating procedure for studying the sleep phenotypes in a large population cohort is proposed.It is intended for academic researchers in investigating the sleep phenotypes in conjunction with the clinical ...A standard operating procedure for studying the sleep phenotypes in a large population cohort is proposed.It is intended for academic researchers in investigating the sleep phenotypes in conjunction with the clinical sleep disorders assessment guidelines.The protocol refers to the definitive American Academy of Sleep Medicine(AASM)manual for setting polysomnography(PSG)technical specifications,scoring of sleep and associated events,etc.On this basis,it not only provides a standardized procedure of sleep interview,sleep-relevant questionnaires,and laboratory-based PSG test,but also offers a comprehensive process of sleep data analysis,phenotype extraction,and data storage.Both the objective sleep data recorded by PSG test and subjective sleep information obtained by the sleep interview and sleep questionnaires are involved in the data acquisition procedure.Subsequently,sleep phenotypes can be characterized by observable/inconspicuous physiological patterns during sleep from PSG test or can be marked by sleeping habits like sleep quality,sleep latency,sleep duration,habitual sleep efficiency,sleep disturbances,daytime dysfunction,etc.,from sleep interview or questionnaires derived.In addition,solutions to the problems that may be encountered during the protocol are summarized and addressed.With the protocol,it can significantly improve scientific research efficiency and reduce unnecessary workload in large population cohort studies.Moreover,it is also expected to provide a valuable reference for researchers to conduct systematic sleep research.展开更多
The effects of alkaline treatment on the physical properties of ZSM-5 catalysts and on their activities for methanol to aromatics conversion have been investigated. A mild alkaline treatment （0.2 and 0.3 mol/L NaOH）...The effects of alkaline treatment on the physical properties of ZSM-5 catalysts and on their activities for methanol to aromatics conversion have been investigated. A mild alkaline treatment （0.2 and 0.3 mol/L NaOH） created mesopores in the parent zeolite with no obvious effect on acidity. The presence of mesopores gives the catalyst a longer lifetime and higher selectivity for aromatics. Treatment with 0.4 mol/L NaOH decreased the number of Bronsted acid sites due to dealumination and desilication, which resulted in a lower deactivation rate. In addition, more mesopores were produced than with the mild alkaline treatment. As a result, the lifetime of the sample treated with 0.4 mol/L NaOH was almost five times that of the parent ZSM-5. Treatment with a higher alkaline concentration （0.5 mol/L） greatly reduced the number of Bronsted acid sites and the number ofmicropores resulting in incomplete methanol conversion. When the alkalinetreated catalysts were washed with acid, some of the porosity was restored and a slight increase in selectivity for aromatics was obtained.展开更多
Programmed cell death 4 （PDCD4） is a RNA-binding protein that acts as a tumor suppressor in many cancer types, including colorectal cancer （CRC）. During CRC carcinogenesis, PDCD4 protein levels remarkably decrease...Programmed cell death 4 （PDCD4） is a RNA-binding protein that acts as a tumor suppressor in many cancer types, including colorectal cancer （CRC）. During CRC carcinogenesis, PDCD4 protein levels remarkably decrease, but the underlying molecular mechanism for decreased PDCD4 expression is not fully understood. In this study, we performed bioinformatics analysis to identify miRNAs that potentially target PDCD4. We demonstrated miR-181b as a direct regulator of PDCD4. We further showed that activation of IL6/STAT3 signaling pathway increased miR-181b expression and conse- quently resulted in downregulation of PDCD4 in CRC cells. In addition, we investigated the biological effects of PDCD4 inhibition by miR-181b both in vitro and in vivo and found that miR-181b could promote cell proliferation and migration and suppress apoptosis in CRC cells and accelerate tumor growth in xenograft mice, potentially through targeting PDCD4. Taken toge- ther, this study highlights an oncomiR role for miR-181b in regulating PDCD4 in CRC and suggests that miR-181b may be a novel molecular therapeutic target for CRC.展开更多
In this paper, we investigate the use of ultra weak variational formulation to solve a wave scattering problem in near field optics. In order to capture the sub-scale features of waves, we utilize evanescent wave func...In this paper, we investigate the use of ultra weak variational formulation to solve a wave scattering problem in near field optics. In order to capture the sub-scale features of waves, we utilize evanescent wave functions together with plane wave functions to approximate the local properties of the field. We analyze the global convergence and give an error estimation of the method. Numerical examples are also presented to demonstrate the effectiveness of the strategy.展开更多
The network structure of the smart substation in common use was introduced,and the technical problems of the shared-network of sampled measured value(SMV)and generic object oriented substation event(GOOSE)were analyze...The network structure of the smart substation in common use was introduced,and the technical problems of the shared-network of sampled measured value(SMV)and generic object oriented substation event(GOOSE)were analyzed,such as the processing ability of network device and the intelligent device,the data real-time property and the network reliability,the effects to the substation in the condition of network fault,etc.On this basis,the feasibility of the shared-network of SMV and GOOSE was discussed,the implement scheme was presented,and eventually the solution of the shared-network of SMV and GOOSE was put forward,which based on the applications of the message priority control,restricting the switch number,virtual local area network(VLAN)and GARP multicast registration protocol(GMRP)classification flow control,flow rate limiting,etc.In the test-bed,the cases of shared-network and separate-network of SMV and GOOSE were compared and analyzed,and the result was valuable for reference.展开更多
基金This work was supported by the National Natural Science Foundation of China(Nos.62172242,51901152)Industry University Cooperation Education Program of the Ministry of Education(No.2020021680113)Shanxi Scholarship Council of China.
文摘The transmission line tower will be affected by bad weather and artificial subsidence caused by the foundation and other factors in the power transmission.The tower’s tilt and severe deformation will cause the building to collapse.Many small changes caused the tower’s collapse,but the early staff often could not intuitively notice the changes in the tower’s state.In the current tower online monitoring system,terminal equipment often needs to replace batteries frequently due to premature exhaustion of power.According to the need for real-time measurement of power line tower,this research designed a real-time monitoring device monitoring the transmission tower attitude tilting and foundation state based on the inertial sensor,the acceleration of 3 axis inertial sensor and angular velocity raw data to pole average filtering pre-processing,and then through the complementary filtering algorithm for comprehensive calculation of tilt angle,the system meets the demand for inclined online monitoring of power line poles and towers regarding measurement accuracy,with low cost and power consumption.The optimization multi-sensor cooperative detection and correction measured tilt angle result relative accuracy can reach 1.03%,which has specific promotion and application value since the system has the advantages of unattended and efficient calculation.
基金supported by the National Basic Research Program of China(‘‘973’’Program,No.2013CB035906)Foundation for Innovative Research Groups of the National Natural Science Foundation of China(No.51621092)Heilongjiang Provincial Major Scientific and Technological Project of Applied Technology Research and Development Plan(No.GA14A501)
文摘Previous studies at home and abroad have mainly focused on single dam-break, and little attention has been paid so far to the dam-break of cascade reservoirs.Multi-source flooding, which can lead to three-dimensional turbulent phenomena and superposition effects, is the main difference between the dam-break of cascade and single reservoirs. Detailed descriptions of the coupled numerical simulation of multi-source flooding have little been reported, and the initial wet riverbed is rarely considered in current models. Therefore, in this paper, a method based on the three-dimensional k-ε turbulence model coupled with the volume-of-fluid method is proposed to simulate the dam-break flooding of cascade reservoirs. The upstream river, reservoir, and downstream river are connected by the internal boundary method, and the initial conditions,including river flow and reservoir water, are determined according to the results of the numerical simulation. Coupled numerical simulation of different dam-break flooding is then achieved. The present work solves the challenges presented by the enhancement and superposition of natural river flow, upstream flooding, and downstream flooding.This paper provides a theoretical basis for future studies on the dam-break flood routing of cascade reservoirs.
基金supported by the National Basic Research Program of China (‘‘973’’ Program, No. 2013CB035906)the National Natural Science Foundation of China (No. 51439005)the Foundation for Innovative Research Groups of the National Natural Science Foundation of China (No. 51621092)
文摘Channel engineering stability with underground goafs is a complex three-dimensional problem, especially when considering channel leakage, and is influenced by a number of processes, such as seepage, fluid structure interaction(FSI), modeling, and selection of geological mechanical parameters. In this study, stability finite element analysis by one-way FSI was performed by establishing an integrated 3D engineering geological model. The extended Fourier amplitude sensitivity test was used to quantitatively assess the first-order and total sensitivities of the engineering model to critical geological mechanical parameters. Results illustrate that the channel engineering deformation is under a reasonable range and the elastic modulus is the highest total sensitivity parameter for the channel tilt and curvature at 0.7395 and 0.7525, respectively. Moreover, the most observable coupling effects for the curvature and horizontal strain are cohesion(0.1933)and density(0.7410), respectively.
基金The authors gratefully acknowledge the National Natural Science Foundation(31770600)for its financial support.
文摘Understanding the assembly and spatial arrangement of bamboo cell wall components is crucial for its optimal utilization.Bamboo cell walls consist of aggregates of cellulose microfibrils and matrix.In the present study,the size and arrangement of cellulose microfibril aggregates in the cell walls of sclerenchyma fibers and parenchyma cells in moso bamboo were investigated with NMR and FE-SEM.The NMR measurement showed that the characteristic sizes of the microfibril aggregates of fibers and parenchyma cells were approximately 25.8 nm and 18.8 nm,respectively.Furthermore,high-resolution SEM showed the size of microfibril aggregates varied little across the cell wall of sclerenchyma fiber.However,there were significant size differences between the broad and narrow lamellae both in fiber and parenchyma cells,which is thought to be closely related to the orientation of microfibrils in these layers.The microfibril aggregates in the fibers mainly appear in a random arrangement,although occasionally in a radial or tangential arrangement in individual cell.Parenchyma cells have a relatively thinner cell wall layers,in which microfibril aggregates appear in a concentric lamellar arrangement.
文摘The concept of optimal Delaunay triangulation (ODT) and the corresponding error-based quality metric are first introduced. Then one kind of mesh smoothing algorithm for tetrahedral mesh based on the concept of ODT is examined. With regard to its problem of possible producing illegal elements, this paper proposes a modified smoothing scheme with a constrained optimization model for tetrahedral mesh quality improvement. The constrained optimization model is converted to an unconstrained one and then solved by integrating chaos search and BFGS (Broyden-Fletcher-Goldfarb-Shanno) algorithm efficiently. Quality improvement for tetrahedral mesh is finally achieved by alternately applying the presented smoothing scheme and re-triangulation. Some testing examples are given to demonstrate the effectiveness of the proposed approach.
文摘Operating Room is an important place for surgical diagnosis and treatment and rescue of patients. With the rapid development of medical technology, high, precision, sharp continuous development, operating room safety management is particularly important. The error of the counting of the surgical articles causes the foreign body left in the patient’s body, which will cause irreversible damage to the patient and even cause the medical dispute and touch the legal problem. Operation items inventory system is an important working system in the operating room. Scientific and standardized methods and systems for counting surgical instruments and dressings during operation can prevent foreign bodies from being left in the body, prevent errors and accidents in the operating room, and are very important for ensuring the safety of the operation of patients. In order to ensure the safety of patients, it is necessary to ensure the correct inventory of surgical items. The factors affecting the accuracy of item counting in the operating room and the preventive measures are summarized as follows.
基金the"USTC Research Funds of the Double First-Class Initiative",the International Partnership Program of Chinese Academy of Sciences(113111KYSB20190030)the Innovative Scientific Program of Institute of High Energy Physics。
文摘We present a study of the measurement of the effective weak mixing angle parameter(sin^(2)θ^(l)_(eff))at the Circular Electron Positron Collider(CEPC).As a fundamental physics parameter,sin^(2)θ_(eff)^(l) plays a key role not only in the global test of the standard model electroweak sector,but also in constraining the potential beyond standard model new physics at the high energy frontier.CEPC proposes a two year running period around the Z boson mass pole at high instataneous luminosity,providing a large data sample with 4 × 10^(12)Z candidates generated in total.It allows a high precision measurement of sin^(2)θ^(l)_(eff) both in the lepton and quark final states,where the uncertainty can be one order of magnitude lower than any previous measurement at the LEP,SLC,Tevatron,and LHC.It will improve the overall precision of the sin^(2)θ^(l)_(eff) experimental determination to be comparable to the preicision of the theoretical calculation with two-loop radiative corrections,and it will also provide direct comparisons between different final states.In this paper,we also study the measurement of sin^(2)θ^(l)_(eff) in the high mass region.Taking data for one month,the precision of sin^(2)θ^(l)_(eff) measured at 130 GeV from b quark final state is 0.00010,which will be an important experimental observation on the energy-running effect of sin^(2)θ^(l)_(eff).
基金supported by the Shanghai Municipal Science and Technology Major Project under Grant 2017SHZDZX01.
文摘A standard operating procedure for studying the sleep phenotypes in a large population cohort is proposed.It is intended for academic researchers in investigating the sleep phenotypes in conjunction with the clinical sleep disorders assessment guidelines.The protocol refers to the definitive American Academy of Sleep Medicine(AASM)manual for setting polysomnography(PSG)technical specifications,scoring of sleep and associated events,etc.On this basis,it not only provides a standardized procedure of sleep interview,sleep-relevant questionnaires,and laboratory-based PSG test,but also offers a comprehensive process of sleep data analysis,phenotype extraction,and data storage.Both the objective sleep data recorded by PSG test and subjective sleep information obtained by the sleep interview and sleep questionnaires are involved in the data acquisition procedure.Subsequently,sleep phenotypes can be characterized by observable/inconspicuous physiological patterns during sleep from PSG test or can be marked by sleeping habits like sleep quality,sleep latency,sleep duration,habitual sleep efficiency,sleep disturbances,daytime dysfunction,etc.,from sleep interview or questionnaires derived.In addition,solutions to the problems that may be encountered during the protocol are summarized and addressed.With the protocol,it can significantly improve scientific research efficiency and reduce unnecessary workload in large population cohort studies.Moreover,it is also expected to provide a valuable reference for researchers to conduct systematic sleep research.
文摘The effects of alkaline treatment on the physical properties of ZSM-5 catalysts and on their activities for methanol to aromatics conversion have been investigated. A mild alkaline treatment （0.2 and 0.3 mol/L NaOH） created mesopores in the parent zeolite with no obvious effect on acidity. The presence of mesopores gives the catalyst a longer lifetime and higher selectivity for aromatics. Treatment with 0.4 mol/L NaOH decreased the number of Bronsted acid sites due to dealumination and desilication, which resulted in a lower deactivation rate. In addition, more mesopores were produced than with the mild alkaline treatment. As a result, the lifetime of the sample treated with 0.4 mol/L NaOH was almost five times that of the parent ZSM-5. Treatment with a higher alkaline concentration （0.5 mol/L） greatly reduced the number of Bronsted acid sites and the number ofmicropores resulting in incomplete methanol conversion. When the alkalinetreated catalysts were washed with acid, some of the porosity was restored and a slight increase in selectivity for aromatics was obtained.
文摘Programmed cell death 4 （PDCD4） is a RNA-binding protein that acts as a tumor suppressor in many cancer types, including colorectal cancer （CRC）. During CRC carcinogenesis, PDCD4 protein levels remarkably decrease, but the underlying molecular mechanism for decreased PDCD4 expression is not fully understood. In this study, we performed bioinformatics analysis to identify miRNAs that potentially target PDCD4. We demonstrated miR-181b as a direct regulator of PDCD4. We further showed that activation of IL6/STAT3 signaling pathway increased miR-181b expression and conse- quently resulted in downregulation of PDCD4 in CRC cells. In addition, we investigated the biological effects of PDCD4 inhibition by miR-181b both in vitro and in vivo and found that miR-181b could promote cell proliferation and migration and suppress apoptosis in CRC cells and accelerate tumor growth in xenograft mice, potentially through targeting PDCD4. Taken toge- ther, this study highlights an oncomiR role for miR-181b in regulating PDCD4 in CRC and suggests that miR-181b may be a novel molecular therapeutic target for CRC.
基金The authors would like to thank the reviewers and Dr.Zheng Enxi for many valuable suggcstions. This work is supported by the National Natural Science Foundation of China （Grant No. 11371172, 51178001）, Science and technology research project of the education department of Jilin Province （Grant No. 2014213）.
文摘In this paper, we investigate the use of ultra weak variational formulation to solve a wave scattering problem in near field optics. In order to capture the sub-scale features of waves, we utilize evanescent wave functions together with plane wave functions to approximate the local properties of the field. We analyze the global convergence and give an error estimation of the method. Numerical examples are also presented to demonstrate the effectiveness of the strategy.
文摘The network structure of the smart substation in common use was introduced,and the technical problems of the shared-network of sampled measured value(SMV)and generic object oriented substation event(GOOSE)were analyzed,such as the processing ability of network device and the intelligent device,the data real-time property and the network reliability,the effects to the substation in the condition of network fault,etc.On this basis,the feasibility of the shared-network of SMV and GOOSE was discussed,the implement scheme was presented,and eventually the solution of the shared-network of SMV and GOOSE was put forward,which based on the applications of the message priority control,restricting the switch number,virtual local area network(VLAN)and GARP multicast registration protocol(GMRP)classification flow control,flow rate limiting,etc.In the test-bed,the cases of shared-network and separate-network of SMV and GOOSE were compared and analyzed,and the result was valuable for reference.
