The physicochemical properties and composition of coix seed oil produced by Monascus purpureus fermentation and supercritical CO_(2)extraction were determined.Anti-lipid-oxidation and edible safety were evaluated usin...The physicochemical properties and composition of coix seed oil produced by Monascus purpureus fermentation and supercritical CO_(2)extraction were determined.Anti-lipid-oxidation and edible safety were evaluated using a cholesterol-fish oil model,acute oral toxicity assay,and genetic toxicity assay in vitro and in vivo,respectively.The results show that the extraction oil from fermented coix seed(FCS-O)had good physicochemical quality and abundant active components with physiological function.In particular,γ-tocotrienol,γ-oryzanol,coixenolide and oleic acid concentrations reached 72.83μg/g,745.96μg/g,9.65 mg/g and 316.58 mg/100 g DW,respectively.The FCS-O exhibited higher antioxidant capability in inhibiting lipid oxidation and peroxidation.Compared to the blank control,the concentrations of 7-ketocholestreol and peroxide only were 8.42μg/mL and 16.16 mmol/kg at 168 h of oxidation(P<0.01).In addition,the FCS-O has been confirmed to be a very safe edible oil,with no acute toxicity(LD50>10 g/kg bw,considered actually non-toxic)and no induced mutagenicity,cytotoxicity or genotoxicity.These results serve as a good safety reference for future application of the oil from fermented coix seed.The development and utilization of this kind of oil will be beneficial as a food,food ingredient,nutritional supplement,or natural food antioxidant to promote good health function.展开更多
This paper investigates the feasibility of using a Li-Baker detector based on a modulated Gaussian beam to detect gravitational waves in the GHz band.The first-order perturbation photon fluxes(PPF,signal of the detect...This paper investigates the feasibility of using a Li-Baker detector based on a modulated Gaussian beam to detect gravitational waves in the GHz band.The first-order perturbation photon fluxes(PPF,signal of the detector)and the background photon fluxes(BPF,main noise of the detector),which vary with time,and the transverse distance are calculated.The results show that their propagation directions and energy densities are much different in some areas.Apart from BPF,we also consider two other important noises:diffraction noise and shot noise.In the simulation,it is found that the diffraction noise and shot noise are both lower than the signal level.Meanwhile,the main noise(BPF)can be eliminated when the receiving screen is located in certain special transverse areas where the BPF direction is opposite to that of PPF.Thus,the signal to noise ratio(SNR)obtained using our detection method can reach up to 320 in some transverse areas.These results are beneficial for the design of the Li-Baker detector.展开更多
基金supported by Natural Science Foundation of China(32260583)the Agriculture Committee of Guizhou Province[(2017)106&(2018)81]the Talent Introduction Program of Guizhou University[(2021)76].
文摘The physicochemical properties and composition of coix seed oil produced by Monascus purpureus fermentation and supercritical CO_(2)extraction were determined.Anti-lipid-oxidation and edible safety were evaluated using a cholesterol-fish oil model,acute oral toxicity assay,and genetic toxicity assay in vitro and in vivo,respectively.The results show that the extraction oil from fermented coix seed(FCS-O)had good physicochemical quality and abundant active components with physiological function.In particular,γ-tocotrienol,γ-oryzanol,coixenolide and oleic acid concentrations reached 72.83μg/g,745.96μg/g,9.65 mg/g and 316.58 mg/100 g DW,respectively.The FCS-O exhibited higher antioxidant capability in inhibiting lipid oxidation and peroxidation.Compared to the blank control,the concentrations of 7-ketocholestreol and peroxide only were 8.42μg/mL and 16.16 mmol/kg at 168 h of oxidation(P<0.01).In addition,the FCS-O has been confirmed to be a very safe edible oil,with no acute toxicity(LD50>10 g/kg bw,considered actually non-toxic)and no induced mutagenicity,cytotoxicity or genotoxicity.These results serve as a good safety reference for future application of the oil from fermented coix seed.The development and utilization of this kind of oil will be beneficial as a food,food ingredient,nutritional supplement,or natural food antioxidant to promote good health function.
基金the National Natural Science Foundation of China(12147102)the Youth Science and Technology Innovation Research Team of Sichuan Province,China(21CXTD0038)。
文摘This paper investigates the feasibility of using a Li-Baker detector based on a modulated Gaussian beam to detect gravitational waves in the GHz band.The first-order perturbation photon fluxes(PPF,signal of the detector)and the background photon fluxes(BPF,main noise of the detector),which vary with time,and the transverse distance are calculated.The results show that their propagation directions and energy densities are much different in some areas.Apart from BPF,we also consider two other important noises:diffraction noise and shot noise.In the simulation,it is found that the diffraction noise and shot noise are both lower than the signal level.Meanwhile,the main noise(BPF)can be eliminated when the receiving screen is located in certain special transverse areas where the BPF direction is opposite to that of PPF.Thus,the signal to noise ratio(SNR)obtained using our detection method can reach up to 320 in some transverse areas.These results are beneficial for the design of the Li-Baker detector.
