An integrated optical coherence tomography(OCT)and video rigid laryngoscope have been designed to acquire surface and subsurface tissue images of larynx simultaneously.The dual-modality system that is based on a commo...An integrated optical coherence tomography(OCT)and video rigid laryngoscope have been designed to acquire surface and subsurface tissue images of larynx simultaneously.The dual-modality system that is based on a common-path design with components as few as possible effec-tively maintains the light transmittance without compromising the imaging quality.In this paper,the field of view(FOV)of the system can reach 70°by use of a gradient index(GRIN)lens as the relay element and a four-lens group as the distal objective,respectively.The simulation showed that the modulation transfer function(MTF)value in each FOV of the rigid video endoscope at 160 lp/mm is greater than 0.1 while the root mean square(RMS)radii of the OCT beam in the center and edge of the FOV are 14.948μm and 73.609μm,respectively.The resolutions of both OCT and video endoscope meet the requirement of clinical application.In addition,all the components of the system are spherical,therefore the system can be of low cost and easy to assemble.展开更多
In this paper,we propose and demonstrate a dual-beam delay-encoded Doppler spectral domain optical coherence tomography(OCT) system for in vivo measurement of absolute retinal blood velocity and flow with arbitrary or...In this paper,we propose and demonstrate a dual-beam delay-encoded Doppler spectral domain optical coherence tomography(OCT) system for in vivo measurement of absolute retinal blood velocity and flow with arbitrary orientation.The incident beam is split by a beam displacer into two probe beams of the single-spectrometer spectral domain OCT system with orthogonal polarization states and an optical path length delay.We validate our approach with a phantom and in vivo experiments of human retinal blood flow,respectively.展开更多
基金funded by the National Key Research and Development Program of China(No.2017YFC0112401)the National Natural Science Foundation of China(Nos.61975246,61505267)the Science and Technology Program of Guangzhou(Nos.201607010167 and 201903010065)
文摘An integrated optical coherence tomography(OCT)and video rigid laryngoscope have been designed to acquire surface and subsurface tissue images of larynx simultaneously.The dual-modality system that is based on a common-path design with components as few as possible effec-tively maintains the light transmittance without compromising the imaging quality.In this paper,the field of view(FOV)of the system can reach 70°by use of a gradient index(GRIN)lens as the relay element and a four-lens group as the distal objective,respectively.The simulation showed that the modulation transfer function(MTF)value in each FOV of the rigid video endoscope at 160 lp/mm is greater than 0.1 while the root mean square(RMS)radii of the OCT beam in the center and edge of the FOV are 14.948μm and 73.609μm,respectively.The resolutions of both OCT and video endoscope meet the requirement of clinical application.In addition,all the components of the system are spherical,therefore the system can be of low cost and easy to assemble.
基金supported by the National Natural Science Foundation of China (Nos. 61975246 and 61505267)Research Fund for Guangxi Distinguished Experts
文摘In this paper,we propose and demonstrate a dual-beam delay-encoded Doppler spectral domain optical coherence tomography(OCT) system for in vivo measurement of absolute retinal blood velocity and flow with arbitrary orientation.The incident beam is split by a beam displacer into two probe beams of the single-spectrometer spectral domain OCT system with orthogonal polarization states and an optical path length delay.We validate our approach with a phantom and in vivo experiments of human retinal blood flow,respectively.
