We present a case of Staphylococcus aurous tricuspid valve endocarditis without any risk factors (intravenous drug users, with pacemaker or central venous lines and with congenital heart disease). Transthoracic echoca...We present a case of Staphylococcus aurous tricuspid valve endocarditis without any risk factors (intravenous drug users, with pacemaker or central venous lines and with congenital heart disease). Transthoracic echocardiography, as first line examination, showed the vegetations on tricuspid valve. In our case, the diagnosis and treatment of right-sided infective endocarditis without any inducement were extremely difficult. Therefore, once a patient comes out with fever, the blood culture remains positive for gram-positive bacterium, and the infectious location still unknown, then the infective endocarditis should be considered. In addition, surgical measure is also an important therapy for right-sided infective endocarditis.展开更多
Erdheim-Chester disease (ECD) is an uncommon non-Langerhans cell histiocytosis that affects multiple body systems and can present clinically in a myriad of ways. We report the case of a 29-year-old man presented with ...Erdheim-Chester disease (ECD) is an uncommon non-Langerhans cell histiocytosis that affects multiple body systems and can present clinically in a myriad of ways. We report the case of a 29-year-old man presented with fever and diffuse bone pain. Physical examination showed bilateral and symmetrical long bone pain, especially the knees. Radiographs showed multiple mixed bone lesions with sclerotic and lytic areas of the femora, tibiae, and fibula. Biopsy of the tibial area displayed foamy lipid-laden histiocytes, confirming the diagnosis of ECD.展开更多
Dear Editor,The outbreak of the COVID‐19 that occurred in late 2019 has posed a remarkable threat to public health around the world.It is known that SARS-CoV-2 is a genetically diverse group that mutates continuously...Dear Editor,The outbreak of the COVID‐19 that occurred in late 2019 has posed a remarkable threat to public health around the world.It is known that SARS-CoV-2 is a genetically diverse group that mutates continuously,leading to the emergence of multiple variants.1 Potential variants of concern(VOCs),variants of interest(VOIs),or variants under monitoring(VUMs)are regularly assessed based on the risk posed to global public health.Following the identification of a novel variant in South Africa on 24 November 2021,WHO designated Omicron(clade GRA,PANGO lineage B.1.1.529 and descendants BA.1 and BA.2)as the fifth SARS-CoV-2 VOC 2 days later due to its large number of variations.展开更多
文摘We present a case of Staphylococcus aurous tricuspid valve endocarditis without any risk factors (intravenous drug users, with pacemaker or central venous lines and with congenital heart disease). Transthoracic echocardiography, as first line examination, showed the vegetations on tricuspid valve. In our case, the diagnosis and treatment of right-sided infective endocarditis without any inducement were extremely difficult. Therefore, once a patient comes out with fever, the blood culture remains positive for gram-positive bacterium, and the infectious location still unknown, then the infective endocarditis should be considered. In addition, surgical measure is also an important therapy for right-sided infective endocarditis.
文摘Erdheim-Chester disease (ECD) is an uncommon non-Langerhans cell histiocytosis that affects multiple body systems and can present clinically in a myriad of ways. We report the case of a 29-year-old man presented with fever and diffuse bone pain. Physical examination showed bilateral and symmetrical long bone pain, especially the knees. Radiographs showed multiple mixed bone lesions with sclerotic and lytic areas of the femora, tibiae, and fibula. Biopsy of the tibial area displayed foamy lipid-laden histiocytes, confirming the diagnosis of ECD.
基金the Three-Year Action Plan of Shanghai Public Health System Construction-Key Discipline Construction(2020–2022,Grant No.GWV-10.1-XK03)the National Natural Science Foundation of China(Grant No.81872673)the Three-Year Initiative Plan for Strengthening Public Health System Construction in Shanghai(2020–2022,Grant No.GWV-10.1-XK23).
文摘Dear Editor,The outbreak of the COVID‐19 that occurred in late 2019 has posed a remarkable threat to public health around the world.It is known that SARS-CoV-2 is a genetically diverse group that mutates continuously,leading to the emergence of multiple variants.1 Potential variants of concern(VOCs),variants of interest(VOIs),or variants under monitoring(VUMs)are regularly assessed based on the risk posed to global public health.Following the identification of a novel variant in South Africa on 24 November 2021,WHO designated Omicron(clade GRA,PANGO lineage B.1.1.529 and descendants BA.1 and BA.2)as the fifth SARS-CoV-2 VOC 2 days later due to its large number of variations.