Selenium is an essential trace element for humans and animals.As the active center of selenoproteins,the addition of selenium is beneficial to enhance the antioxidant ability.However,the high cost limits the applicati...Selenium is an essential trace element for humans and animals.As the active center of selenoproteins,the addition of selenium is beneficial to enhance the antioxidant ability.However,the high cost limits the application of organic Se in agriculture animal production.Selenized glucose(SeGlu)is a newly invented organoselenium material with good stability,low toxicity and low cost.This assay found that SeGlu was able to increase selenium deposition in liver of newborn broilers,and enhance the antioxidant capacity of liver by elevating the activities of antioxidant enzymes such as total superoxide dismutase and glutathione peroxidase.This paper as the first example clarifying the mechanism of SeGlu to enhance the antioxidant ability of chicks,shows that SeGlu can be used as an organic selenium enrichment additive for early nutrition of poultry.As a cross-discipline study involving chemistry,biology and agriculture animal science,the work may be beneficial for studies in related fields and prompt the development of the selenium science.展开更多
Selenized glucose can be easily prepared via the selenization reaction of glucose using in situ generated NaHSe as the selenization reagent.The technique has been industrialized to produce the chemical in kilogram sca...Selenized glucose can be easily prepared via the selenization reaction of glucose using in situ generated NaHSe as the selenization reagent.The technique has been industrialized to produce the chemical in kilogram scale,making it an easily available mate rial in laborato ry presently.The selenized glucose may be widely used as the starting material for the preparation of selenium-containing catalysts,as the organoselenium additive for feeds,and as the efficient selenium-enriched foliar fertilizers.In this work,we found that treating Fusarium graminearum,a fungal pathogen inciting wheat scab disease,with selenium glucose could significantly inhibit the generation of the deoxynivalenol(DON)toxin,which might be a breakthrough for reducing the detriment of the wheat scab disease.展开更多
基金supported by the Open Project of Jiangsu Key Laboratory of Animal genetic Breeding and Molecular Design(No.AGBMD202202)the Jiangsu Agricultural Science and Technology Innovation Fund(Nos.[CX(21)3131]and[CX(20)3010])+2 种基金the“JBGS”Project of Seed Industry Revitalization in Jiangsu Province(Nos.[JBGS[2021]027 and JBGS[2021]105])the Science and Education Integration Project of Yangzhou University(No.[KJRH202115])Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)。
文摘Selenium is an essential trace element for humans and animals.As the active center of selenoproteins,the addition of selenium is beneficial to enhance the antioxidant ability.However,the high cost limits the application of organic Se in agriculture animal production.Selenized glucose(SeGlu)is a newly invented organoselenium material with good stability,low toxicity and low cost.This assay found that SeGlu was able to increase selenium deposition in liver of newborn broilers,and enhance the antioxidant capacity of liver by elevating the activities of antioxidant enzymes such as total superoxide dismutase and glutathione peroxidase.This paper as the first example clarifying the mechanism of SeGlu to enhance the antioxidant ability of chicks,shows that SeGlu can be used as an organic selenium enrichment additive for early nutrition of poultry.As a cross-discipline study involving chemistry,biology and agriculture animal science,the work may be beneficial for studies in related fields and prompt the development of the selenium science.
基金the National Key R&D Program:Intergovernmental Key Items for International Scientific and Technological Innovation Cooperation(No.2018YFE0107700)the open funds of the Key Laboratory of Plant Functional Genomics of the Ministry of Education(No.ML201904)+1 种基金Jiangsu Provincial Six Talent Peaks Project(No.XCL-090)Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)。
文摘Selenized glucose can be easily prepared via the selenization reaction of glucose using in situ generated NaHSe as the selenization reagent.The technique has been industrialized to produce the chemical in kilogram scale,making it an easily available mate rial in laborato ry presently.The selenized glucose may be widely used as the starting material for the preparation of selenium-containing catalysts,as the organoselenium additive for feeds,and as the efficient selenium-enriched foliar fertilizers.In this work,we found that treating Fusarium graminearum,a fungal pathogen inciting wheat scab disease,with selenium glucose could significantly inhibit the generation of the deoxynivalenol(DON)toxin,which might be a breakthrough for reducing the detriment of the wheat scab disease.
