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Immunological battlefield in gastric cancer and role of immunotherapies 被引量:5
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作者 minyu wang Rita A Busuttil +2 位作者 Sharon Pattison Paul J Neeson Alex Boussioutas 《World Journal of Gastroenterology》 SCIE CAS 2016年第28期6373-6384,共12页
Like the wars predating the First World War where human foot soldiers were deemed tools in the battlefield against an enemy, so too are the host immune cells of a patient battling a malignant gastric cancer. Indeed, t... Like the wars predating the First World War where human foot soldiers were deemed tools in the battlefield against an enemy, so too are the host immune cells of a patient battling a malignant gastric cancer. Indeed, the tumour microenvironment resembles a battlefield, where the patient's immune cells are the defence against invading tumour cells. However, the relationship between different immune components of the host response to cancer is more complex than an "us against them" model. Components of the immune system inadvertently work against the interests of the host and become pro-tumourigenic while other components soldier on against the common enemy – the tumour cell. 展开更多
关键词 IMMUNE Gastric cancer IMMUNE therapy IMMUNOLOGY TUMOUR microenvironment
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The spatial-temporal differentiation of green land use in Beijing-Tianjin-Hebei urban agglomeration 被引量:2
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作者 Xiaoqing Pang Deqi wang +2 位作者 Fan Zhang minyu wang Ningze Cao 《Chinese Journal of Population,Resources and Environment》 2018年第4期343-354,共12页
As the space carrier of the construction of ecological civilization, land's green and efficient utilization is an important guarantee for realizing national sustainable development. Based on traditional land evalu... As the space carrier of the construction of ecological civilization, land's green and efficient utilization is an important guarantee for realizing national sustainable development. Based on traditional land evaluation, this paper scientifically defines the green land use, puts land as one of the production factors, and brings energy consumption, environmental pollution, etc. into the input-output system to measure the green land utilization efficiency of the urban construction land of Beijing-TianjinHebei Urban Agglomeration from 2006 to 2016. The study shows that the overall efficiency variation of the urban agglomeration is related with the land and environment policies. Efficiency of 2016 is higher than that of 2006, and energy and environment are the principal factors affecting the green land use. The efficiency of each city is positively correlated with its economic development, negatively correlated with the construction land expansion. Efficiency gaps in different cities are expanding.There is positive correlation with overall weak space between cities, and the partial spatial agglomeration phenomenon appears. Therefore, the green land use efficiency could be improved by improving land utilization efficiency, coordinating economic growth of construction land utilization with environmental protection and taking feasible ways to transregional renovation of the stock ecological land utilization, etc. 展开更多
关键词 Green land use SUPER-EFFICIENCY SBM(SSBM) BEIJING-TIANJIN-HEBEI urban AGGLOMERATION
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