The brown mussel Perna perna(Linnaeus,1758)is a valuable resource for aquaculture in tropical and subtropical coastal regions.It presents desirable characteristics for biomonitoring,including being sessile,widely dist...The brown mussel Perna perna(Linnaeus,1758)is a valuable resource for aquaculture in tropical and subtropical coastal regions.It presents desirable characteristics for biomonitoring,including being sessile,widely distributed and abundant,and is a filter-feeder able to accumulate several classes of pollutants(e.g.,metals,hydrocarbons,among others).Mussels’biological responses to pollution exposure can be measured as biomarkers,which include alterations ranging from molecular to physiological levels,to estimate the degree of environmental contamination and its effects on biota.This full review compiles two decades(2000–2020)of literature concerning biological effects on P.perna mussel caused by environmental pollutants(i.e.,metals,hydrocarbons,and emerging pollutants),considering environmental and farm-based biomonitoring.Biochemical markers related to mussels’oxidative status were efficient for the biomonitoring of metals(i.e.,antioxidant enzymes associated with oxidative damage in biomolecules).Genotoxicity and cytotoxicity indicators(i.e.,comet,micronucleus,and neutral red assays)provided a depiction of hydrocarbon contamination.The neutral red assay gave a time-concentration cytotoxic response to a wide range of pollutants,including emerging pollutants(e.g.,pharmaceuticals and biocides)and hydrocarbons.Perna perna hemocyte parameters provided a useful approach for biocide biomonitoring.This paper summarizes useful biomarkers from molecular to physiological levels in this mussel species used to identify and quantify the degree of coastal pollution.An integrated biomarker analysis may provide a way to overcome possible biomarker variations and assess multi-polluted sites.Nevertheless,it is necessary to investigate biomarker variations according to natural factors(e.g.,season and gonad maturation stage)to standardize them for trustworthy biomonitoring.展开更多
基金financed in part by the Coordination of Superior Level Staff Improvement–Brazil(CAPES)–Finance Code 001–[Fernanda Silva dos Santos–doctoral fellowship 88882.457000/2019.1]Federal University of the State of Rio de Janeiro(UNIRIO)–[INOVA UNIRIO IN01/2019 attributed to Natascha Krepsky and INOVA UNIRIO IN01/2019 attributed to Raquel A.F.Neves]+1 种基金Carlos Chagas Filho Foundation for Research Support in the State of Rio de Janeiro-(FAPERJ)–[Number E-26/202.794/2018(CNE)]National Council for Scientific and Technological Development(CNPq)–[Number 301964/2018-1]attributed to Valéria Laneuville Teixeira。
文摘The brown mussel Perna perna(Linnaeus,1758)is a valuable resource for aquaculture in tropical and subtropical coastal regions.It presents desirable characteristics for biomonitoring,including being sessile,widely distributed and abundant,and is a filter-feeder able to accumulate several classes of pollutants(e.g.,metals,hydrocarbons,among others).Mussels’biological responses to pollution exposure can be measured as biomarkers,which include alterations ranging from molecular to physiological levels,to estimate the degree of environmental contamination and its effects on biota.This full review compiles two decades(2000–2020)of literature concerning biological effects on P.perna mussel caused by environmental pollutants(i.e.,metals,hydrocarbons,and emerging pollutants),considering environmental and farm-based biomonitoring.Biochemical markers related to mussels’oxidative status were efficient for the biomonitoring of metals(i.e.,antioxidant enzymes associated with oxidative damage in biomolecules).Genotoxicity and cytotoxicity indicators(i.e.,comet,micronucleus,and neutral red assays)provided a depiction of hydrocarbon contamination.The neutral red assay gave a time-concentration cytotoxic response to a wide range of pollutants,including emerging pollutants(e.g.,pharmaceuticals and biocides)and hydrocarbons.Perna perna hemocyte parameters provided a useful approach for biocide biomonitoring.This paper summarizes useful biomarkers from molecular to physiological levels in this mussel species used to identify and quantify the degree of coastal pollution.An integrated biomarker analysis may provide a way to overcome possible biomarker variations and assess multi-polluted sites.Nevertheless,it is necessary to investigate biomarker variations according to natural factors(e.g.,season and gonad maturation stage)to standardize them for trustworthy biomonitoring.
