The prickly pear fruit helps in combating viral based infections.It is used to treat diabetes and declared to possess hypoglycemic effects.There is also record of the usage of the fruit in the olden days as a remedy f...The prickly pear fruit helps in combating viral based infections.It is used to treat diabetes and declared to possess hypoglycemic effects.There is also record of the usage of the fruit in the olden days as a remedy for diabetes,lipid disorders,inflammation,ulcers,and pharmacologic side effects.The chemical composition and nutritional values of skin,flesh and seed of prickly pear fruit were investigated and discussed on a dry weight situation.The infrared spectra as well as scanning electron microscopy(SEM)techniques were used to identify the functional groups of carbohydrates,amino acids,and protein.The infrared spectral data of all three(skin,flesh,and seeds)species were recorded and assigned to the presence of distinguish peaks that referred to the three different sugars(glucose,fructose and saccharose)and cyclic aliphatic hydrocarbons moieties.On the other hand,the SEM is a powerful tool to investigate the morphological features of the components.SEM assays were examined on the surfaces of skin,flesh and seed branches showing a small particle that tends to form clusters with different shapes compared to each other.The Energy-dispersive X-ray spectroscopy(EDX)is an analytical technique used for the elemental analysis or chemical characterization of a sample.The EDX spectral technique of the skin,flesh and seeds were confirmed the presence of different essential and useful elements such as carbon,oxygen,magnesium,calcium,potassium,sulfur,aluminum,silicon,chloride,and phosphorus.展开更多
Te(Ⅳ),Se(Ⅳ),V(Ⅲ),Nb(Ⅴ)and Ta(Ⅴ)complexes of indole-3-acetic acid(IAAH)ligand were synthesized,characterized by elemental analysis and various spectroscopic techniques like,IR,1H-NMR,X-ray powder diffraction,UV-Vi...Te(Ⅳ),Se(Ⅳ),V(Ⅲ),Nb(Ⅴ)and Ta(Ⅴ)complexes of indole-3-acetic acid(IAAH)ligand were synthesized,characterized by elemental analysis and various spectroscopic techniques like,IR,1H-NMR,X-ray powder diffraction,UV-Visible,thermogravimetry analysis,magnetic measurements,molar conductance and surface morphology using SEM.All the synthesized complexes of IAAH ligand have 1∶2 stoichiometry of the types[Te(IAA)2(NH 3)2]·2Cl(Ⅰ),[Se(IAA)2(NH 3)2]·2Cl(Ⅱ),[V(IAA)2(NH 3)(Cl)](Ⅲ),[Nb(IAA)2(Cl)3](Ⅳ),and[Ta(IAA)2(Cl)3](Ⅴ).Spectral analysis indicates octahedral geometry for the Te(Ⅳ),Se(Ⅳ)and V(Ⅲ)complexes,whereas both Nb(Ⅴ)and Ta(Ⅴ)have a seven-coordination.The bonding sites are the oxygen atoms of carboxylate group for the deprotonated indole-3-acetic acid(IAA)ligand.The thermogravimetry analysis studies gave evidence for the presence of other coordinated molecules(Cl or NH 3)in the composition of IAA complexes,which were further supported by IR and micro analytical measurements.The higher molar conductance data of tellurium and selenium(Ⅳ)complexes reveal that these chelates are electrolytes,while low conductivity values for the vanadium(Ⅲ),niobium and tantalum(Ⅴ)chelates indicated a non-electrolytes.To test the antibacterial property of the five complexes in this study,four bacterial strains Klebsiella(G-),Escherichia coli(G-),Staphylococcus aureus(G+)and Staphylococcus epidermidis(G+)were used in the investigation.The effects of the five complexes in the cytotoxicity of Caco-2 and Mcf-7 human cancer cell lines were studied Neutral red uptake assay for the estimation of cell viability/cytotoxicity protocol.展开更多
In this work,we have reported the synthesis and spectroscopic characterization of captopril(Cap)coordination compounds:Cu(Cap)·2H 2O,Cr(Cap)·H 2O,Zn(Cap)·3H 2O and Mg(Cap)4.Herein,it is worthily mention...In this work,we have reported the synthesis and spectroscopic characterization of captopril(Cap)coordination compounds:Cu(Cap)·2H 2O,Cr(Cap)·H 2O,Zn(Cap)·3H 2O and Mg(Cap)4.Herein,it is worthily mentioned that the FTIR spectroscopic technique was employed to recognized the nature of coordination between captopril ligand and copper,chromium,zinc and magnesium(Ⅱ)metal ions.In view of the infrared spectroscopic tool,the copper(Ⅱ)metal ion coordinated toward captopril drug ligand through sulfur atom of SH group dependent on the absent of stretching vibration band of—SH.Based on this result,the stretching motion ofνa(COO)shifts clearly indicates that Cu 2+,Cr 2+,Zn 2+and Mg 2+the carboxylic group is employed as coordinative site for all compounds as a metal-ligand coordinative bond.As a general behavior,it is verified that the coordination compound thermal stability(considering the release of captopril molecules,not the release of water molecules)is affected by the metal cation radius:minor radius is associated with higher thermal stability,probably due to a higher metal-captopril bond dissociation enthalpy.展开更多
基金Taif University Researches Supporting Project number(TURSP-2020/01),Taif University,Taif,Saudi Arabia。
文摘The prickly pear fruit helps in combating viral based infections.It is used to treat diabetes and declared to possess hypoglycemic effects.There is also record of the usage of the fruit in the olden days as a remedy for diabetes,lipid disorders,inflammation,ulcers,and pharmacologic side effects.The chemical composition and nutritional values of skin,flesh and seed of prickly pear fruit were investigated and discussed on a dry weight situation.The infrared spectra as well as scanning electron microscopy(SEM)techniques were used to identify the functional groups of carbohydrates,amino acids,and protein.The infrared spectral data of all three(skin,flesh,and seeds)species were recorded and assigned to the presence of distinguish peaks that referred to the three different sugars(glucose,fructose and saccharose)and cyclic aliphatic hydrocarbons moieties.On the other hand,the SEM is a powerful tool to investigate the morphological features of the components.SEM assays were examined on the surfaces of skin,flesh and seed branches showing a small particle that tends to form clusters with different shapes compared to each other.The Energy-dispersive X-ray spectroscopy(EDX)is an analytical technique used for the elemental analysis or chemical characterization of a sample.The EDX spectral technique of the skin,flesh and seeds were confirmed the presence of different essential and useful elements such as carbon,oxygen,magnesium,calcium,potassium,sulfur,aluminum,silicon,chloride,and phosphorus.
基金the Deanship of Scientific Research at Princess Nourah bint Abdulrahman University,through the Research Groups Program Grant no.(RGP-1440-0001)。
文摘Te(Ⅳ),Se(Ⅳ),V(Ⅲ),Nb(Ⅴ)and Ta(Ⅴ)complexes of indole-3-acetic acid(IAAH)ligand were synthesized,characterized by elemental analysis and various spectroscopic techniques like,IR,1H-NMR,X-ray powder diffraction,UV-Visible,thermogravimetry analysis,magnetic measurements,molar conductance and surface morphology using SEM.All the synthesized complexes of IAAH ligand have 1∶2 stoichiometry of the types[Te(IAA)2(NH 3)2]·2Cl(Ⅰ),[Se(IAA)2(NH 3)2]·2Cl(Ⅱ),[V(IAA)2(NH 3)(Cl)](Ⅲ),[Nb(IAA)2(Cl)3](Ⅳ),and[Ta(IAA)2(Cl)3](Ⅴ).Spectral analysis indicates octahedral geometry for the Te(Ⅳ),Se(Ⅳ)and V(Ⅲ)complexes,whereas both Nb(Ⅴ)and Ta(Ⅴ)have a seven-coordination.The bonding sites are the oxygen atoms of carboxylate group for the deprotonated indole-3-acetic acid(IAA)ligand.The thermogravimetry analysis studies gave evidence for the presence of other coordinated molecules(Cl or NH 3)in the composition of IAA complexes,which were further supported by IR and micro analytical measurements.The higher molar conductance data of tellurium and selenium(Ⅳ)complexes reveal that these chelates are electrolytes,while low conductivity values for the vanadium(Ⅲ),niobium and tantalum(Ⅴ)chelates indicated a non-electrolytes.To test the antibacterial property of the five complexes in this study,four bacterial strains Klebsiella(G-),Escherichia coli(G-),Staphylococcus aureus(G+)and Staphylococcus epidermidis(G+)were used in the investigation.The effects of the five complexes in the cytotoxicity of Caco-2 and Mcf-7 human cancer cell lines were studied Neutral red uptake assay for the estimation of cell viability/cytotoxicity protocol.
基金The Deanship of Scientific Research at Princess Nourah bint Abdulrahman University,through the Research Groups Program Grant no.(RGP-1440-0003)
文摘In this work,we have reported the synthesis and spectroscopic characterization of captopril(Cap)coordination compounds:Cu(Cap)·2H 2O,Cr(Cap)·H 2O,Zn(Cap)·3H 2O and Mg(Cap)4.Herein,it is worthily mentioned that the FTIR spectroscopic technique was employed to recognized the nature of coordination between captopril ligand and copper,chromium,zinc and magnesium(Ⅱ)metal ions.In view of the infrared spectroscopic tool,the copper(Ⅱ)metal ion coordinated toward captopril drug ligand through sulfur atom of SH group dependent on the absent of stretching vibration band of—SH.Based on this result,the stretching motion ofνa(COO)shifts clearly indicates that Cu 2+,Cr 2+,Zn 2+and Mg 2+the carboxylic group is employed as coordinative site for all compounds as a metal-ligand coordinative bond.As a general behavior,it is verified that the coordination compound thermal stability(considering the release of captopril molecules,not the release of water molecules)is affected by the metal cation radius:minor radius is associated with higher thermal stability,probably due to a higher metal-captopril bond dissociation enthalpy.
