Changing trends in prevalence of different Plasmodium species with dominance of Plasmodium falciparum malaria infection in Aligarh(India)

Objective:To determine the prevalence of malaria in Aligarh and analyze species dominance in different years over a decade.Methods:Diagnosis of malaria was done using microscopy as gold standard,rapid antigen detection assays and quantitative buffy coat(QBC) assays.Giemsa stained blood smear examination was done,thick and thin films were examined for presence of different Plasmodium spp.Rapid antigen detection assays employing detection of HRP-2 and parasite lactate dehydrogenase antigen(pLDH) by immunochromatography was done in patients whose blood smear found to be negative by conventional Giemsa slide examination.QBC was done in cases where there is strong clinical suspicion of malaria with blood smear negative,in patients with chronic malaria,splenomegaly,or in those patients who had inadequate treatment and for post-treatment follow up.Results:Plasmodium vivax and Plasmodium falciparum were only species detected in our hospital.Overall prevalence of malaria in Aligarh was found to be 8.8%.The maximum prevalence of 20.1%was observed in year 2008 and lowest 2.3%in 2002. Conclusions:High prevalence of malaria is observed in this part of country with dominance of both species particularly Plasmodium falciparum should be monitored and factors accounting for occurrence should be studied to employ effective control measures.

基于有限元和光滑粒子流体动力学的硬质工具钢切屑形貌预测方法研究（英文）

目的:获得有效的高精度切屑形貌仿真方法。创新点:通过比较不同切削参数下采用光滑粒子流体动力学模型和有限元模型仿真获得的切屑形貌,证明光滑粒子流体动力学模型可以很好地实现对节状切屑的仿真,而不需要额外的几何或基于网格的切屑分离准则。方法:基于有限元和光滑粒子流体动力学的切削形貌仿真方法。结论:通过比较不同切削参数下采用光滑粒子流体动力学模型和有限元模型仿真获得的切屑形貌,证明了基于裂纹形成与扩展理论,采用合理疲劳参数的标准Johnson-Cook模型完全可以实现对节状切屑形成过程的仿真,也即无需采用修正的Johnson-Cook模型。同时证明了有限元模型和光滑粒子流体动力学方法均可满足不同切削速度和进给量条件下的切削力和切屑形貌仿真。