We investigated the efficacy of oral desmopressin in the treatment of adult nocturia. In an analytical study between 2007-2009 in Zahedan-Iran, Thirty patients ≥55 years with verified nocturia (≥two voids/night) wer...We investigated the efficacy of oral desmopressin in the treatment of adult nocturia. In an analytical study between 2007-2009 in Zahedan-Iran, Thirty patients ≥55 years with verified nocturia (≥two voids/night) were enrolled. Patients with a history of an obstructive cause of nocturia, those with diseases getting worse by the anti-diuretic affect of desmopressin and those with well-defined curable causes (e.g. cystitis) were excluded. Patients received 0.2 mg of oral desmopressin at bed time for a period of 3 weeks. p < 0.05 was taken as the significant level. All 30 patients enrolled completed the trial. Fourteen (47 %) patients receiving desmopressin had fewer than half the number of nocturnal voids relative to base line (p < 0.001). The mean number of nocturnal voids decreased from 4.6 to 2.4 (p < 0.001). Fatigue (10%), headache (3%) and dizziness (3%) were reported. All adverse events were of mild intensity and there were no instances of hyponatremia. Oral desmopressin is an effective treatment in patients with nocturia and is well-tolerated.展开更多
Objectives: Male circumcision is a commonly-performed surgical procedure in the world. Currently, no consensus exists about the role of the foreskin or the effect circumcision on sexual satisfaction. All previous stud...Objectives: Male circumcision is a commonly-performed surgical procedure in the world. Currently, no consensus exists about the role of the foreskin or the effect circumcision on sexual satisfaction. All previous studies have evaluated the effect of adult circumcision on sexual function. In this study, we responded to “Does circumcision timing have different effects on sexual function?” Methods: Based on circumcision timing (receiving circumcision in less than 18 year olds or older than 18 year olds), the participants were divided into two groups. The following data and measurements were investigated: IIEF-5 score, sexual satisfaction, sexual activity [number of sexual attempt/week] and ability to achieve or maintain an erection. Results: Two hundred and fifty cases including 125 men were investigated in each group. The baseline demographic (age, marital status, education, smoking) was similar in the 2 groups. No statistically significant differences were seen regarding their sexual satisfaction (P = 0.65), sexual activity [number of sexual attempt/week] (P = 0.74), ability to achieve or maintain an erection (P = 0.44), (P = 0.9). The total mean IIEF-5 score was 24.21 +/- 1.94 and 22.23 +/- 1.12 in groups 1 and 2, respectively (p = 0.5). Conclusion: We concluded that the age at which the circumcision is preformed has no effect on the degree of sexual function and satisfaction.展开更多
文摘We investigated the efficacy of oral desmopressin in the treatment of adult nocturia. In an analytical study between 2007-2009 in Zahedan-Iran, Thirty patients ≥55 years with verified nocturia (≥two voids/night) were enrolled. Patients with a history of an obstructive cause of nocturia, those with diseases getting worse by the anti-diuretic affect of desmopressin and those with well-defined curable causes (e.g. cystitis) were excluded. Patients received 0.2 mg of oral desmopressin at bed time for a period of 3 weeks. p < 0.05 was taken as the significant level. All 30 patients enrolled completed the trial. Fourteen (47 %) patients receiving desmopressin had fewer than half the number of nocturnal voids relative to base line (p < 0.001). The mean number of nocturnal voids decreased from 4.6 to 2.4 (p < 0.001). Fatigue (10%), headache (3%) and dizziness (3%) were reported. All adverse events were of mild intensity and there were no instances of hyponatremia. Oral desmopressin is an effective treatment in patients with nocturia and is well-tolerated.
文摘Objectives: Male circumcision is a commonly-performed surgical procedure in the world. Currently, no consensus exists about the role of the foreskin or the effect circumcision on sexual satisfaction. All previous studies have evaluated the effect of adult circumcision on sexual function. In this study, we responded to “Does circumcision timing have different effects on sexual function?” Methods: Based on circumcision timing (receiving circumcision in less than 18 year olds or older than 18 year olds), the participants were divided into two groups. The following data and measurements were investigated: IIEF-5 score, sexual satisfaction, sexual activity [number of sexual attempt/week] and ability to achieve or maintain an erection. Results: Two hundred and fifty cases including 125 men were investigated in each group. The baseline demographic (age, marital status, education, smoking) was similar in the 2 groups. No statistically significant differences were seen regarding their sexual satisfaction (P = 0.65), sexual activity [number of sexual attempt/week] (P = 0.74), ability to achieve or maintain an erection (P = 0.44), (P = 0.9). The total mean IIEF-5 score was 24.21 +/- 1.94 and 22.23 +/- 1.12 in groups 1 and 2, respectively (p = 0.5). Conclusion: We concluded that the age at which the circumcision is preformed has no effect on the degree of sexual function and satisfaction.
