Laser cladding of powder mixture of TiN and SS304 is carried out on an SS304 substrate with the help of fibre laser.The experiments are performed on SS304,as per the Taguchi orthogonal array(L^(16))by different combin...Laser cladding of powder mixture of TiN and SS304 is carried out on an SS304 substrate with the help of fibre laser.The experiments are performed on SS304,as per the Taguchi orthogonal array(L^(16))by different combinations of controllable parameters(microhardness and clad thickness).The microhardness and clad thickness are recorded at all the experimental runs and studied using Taguchi S/N ratio and the optimum controllable parametric combination is obtained.However,an artificial neural network(ANN)identifies different sets of optimal combinations from Taguchi method but they both got almost the same clad thickness and hardness values.The micro-hardness of cladded layer is found to be6.22 times(HV_(0.5)752)the SS304 hardness(HV_(0.5)121).The presence of nitride ceramics results in a higher micro hardness.The cladded surface is free from cracks and pores.The average clad thickness is found to be around 0.6 mm.展开更多
Unrestrained anti-microbial resistance (AMR) among bacterial pathogens has made the management and treatment of post-operative wound infections difficult. This study assessed the current AMR patterns of bacterial isol...Unrestrained anti-microbial resistance (AMR) among bacterial pathogens has made the management and treatment of post-operative wound infections difficult. This study assessed the current AMR patterns of bacterial isolates in post-operative wound infections in a tertiary care hospital in Kathmandu,Nepal. Pus swabs collected from post-operative wound infections and submitted for culture and sensitivity were included in this study. Isolation and identification of the organism was done by standard microbiological methods. Antibiotic susceptibility test was performed by Kirby Bauer disc diffusion method and result was interpreted as per National Committee for Clinical Laboratory Standards (NCCLS) guide lines. Of the 120 pus swabs processed for culture, 96 showed bacterial growth. Staphylococcus aureus 36 (37.5%) was the predominant gram positive isolate and Escherichia coli 24 (25%) was the major gram negative isolate .The infection was most prevalent in the age group 20-40 years. All S. aureus isolates were sensitive to aminoglycosides and vancomycin. Out of 36 S. aureus, 15 (41.66%) isolates were methicillin resistant S. aureus (MRSA). Staphylococcus epidermidis showed high resistance (50%-100%) to all antibiotics but were sensitive to vancomycin. All gram negative isolates showed high resistance against cephalexin (75%-100%) and ceftriaxone (25%-100%). Overall multi-drug resistant isolates were 66.7%. A high level of AMR was observed in gram negative bacterial isolates. Rational use of antibiotics and a regular monitoring of AMR patterns in post-operative wound infections are essential and mandatory to avert further emergence and spread of anti-microbial resistance among bacterial pathogens.展开更多
文摘Laser cladding of powder mixture of TiN and SS304 is carried out on an SS304 substrate with the help of fibre laser.The experiments are performed on SS304,as per the Taguchi orthogonal array(L^(16))by different combinations of controllable parameters(microhardness and clad thickness).The microhardness and clad thickness are recorded at all the experimental runs and studied using Taguchi S/N ratio and the optimum controllable parametric combination is obtained.However,an artificial neural network(ANN)identifies different sets of optimal combinations from Taguchi method but they both got almost the same clad thickness and hardness values.The micro-hardness of cladded layer is found to be6.22 times(HV_(0.5)752)the SS304 hardness(HV_(0.5)121).The presence of nitride ceramics results in a higher micro hardness.The cladded surface is free from cracks and pores.The average clad thickness is found to be around 0.6 mm.
文摘Unrestrained anti-microbial resistance (AMR) among bacterial pathogens has made the management and treatment of post-operative wound infections difficult. This study assessed the current AMR patterns of bacterial isolates in post-operative wound infections in a tertiary care hospital in Kathmandu,Nepal. Pus swabs collected from post-operative wound infections and submitted for culture and sensitivity were included in this study. Isolation and identification of the organism was done by standard microbiological methods. Antibiotic susceptibility test was performed by Kirby Bauer disc diffusion method and result was interpreted as per National Committee for Clinical Laboratory Standards (NCCLS) guide lines. Of the 120 pus swabs processed for culture, 96 showed bacterial growth. Staphylococcus aureus 36 (37.5%) was the predominant gram positive isolate and Escherichia coli 24 (25%) was the major gram negative isolate .The infection was most prevalent in the age group 20-40 years. All S. aureus isolates were sensitive to aminoglycosides and vancomycin. Out of 36 S. aureus, 15 (41.66%) isolates were methicillin resistant S. aureus (MRSA). Staphylococcus epidermidis showed high resistance (50%-100%) to all antibiotics but were sensitive to vancomycin. All gram negative isolates showed high resistance against cephalexin (75%-100%) and ceftriaxone (25%-100%). Overall multi-drug resistant isolates were 66.7%. A high level of AMR was observed in gram negative bacterial isolates. Rational use of antibiotics and a regular monitoring of AMR patterns in post-operative wound infections are essential and mandatory to avert further emergence and spread of anti-microbial resistance among bacterial pathogens.
