·AIM:To determine the risk factors of clinically significant macular edema (CSME) in patients with non-proliferative diabetic retinopathy (NPDR) in a multi-ethnics Malaysian population. ·METHODS:We performed...·AIM:To determine the risk factors of clinically significant macular edema (CSME) in patients with non-proliferative diabetic retinopathy (NPDR) in a multi-ethnics Malaysian population. ·METHODS:We performed a case control study in which 150 patients with bilateral NPDR and CSME in either eye were compared to 150 patients with bilateral NPDR and no CSME in both eyes. CSME and NPDR were graded according to Early Treatment of Diabetic Retinopathy Study criteria. Student’s t-test, odds ratio and multiple logistic regression analysis were performed to analyze the duration of diabetes, body mass index (BMI), blood pressure(BP), total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), triglycerides (TG), fasting blood glucose (FBG), HbA1c, full blood count, serum creatinine and proteinuria between the two groups. ·RESULTS:Both groups were matched in terms of age, gender and ethnicity. Duration of diabetes, total serum cholesterol, serum LDL, FBG, HbA1c and serum creatinine were significantly higher in the CSME group (P <0.05). The hemoglobin, packed cell volume were significantly lower in the CSME group (P <0.05). There was no significant difference for serum HDL, TG, BMI, systolic and diastolic BP. Multiple logistic regression analysis showed that total serum cholesterol and HbA1c had significantly high odds of developing CSME. ·CONCLUSION:HbA1c and total cholesterol are the two most important risk factors associated with CSME in patients with NPDR.展开更多
目的:探讨玻璃体切割术(pars plana vitrectomy,PPV)联合人工晶状体(intraocular lens,IOL)巩膜固定术治疗眼外伤的疗效。方法:系列病例回顾性分析。将马来西亚大学医学中心接受PPV联合IOL巩膜固定术的8例连续性病例纳入研究,其中1例患...目的:探讨玻璃体切割术(pars plana vitrectomy,PPV)联合人工晶状体(intraocular lens,IOL)巩膜固定术治疗眼外伤的疗效。方法:系列病例回顾性分析。将马来西亚大学医学中心接受PPV联合IOL巩膜固定术的8例连续性病例纳入研究,其中1例患者双眼均受伤,共有9眼。对现阶段视力,手术技巧,并发症及术后疗效进行分析。结果:9眼中有8眼(89%)视力提高。术后主要并发症是眼压升高,无缝线破裂。结论:PPV联合IOL巩膜固定术对有眼外伤病史的患者有非常好的疗效。展开更多
文摘·AIM:To determine the risk factors of clinically significant macular edema (CSME) in patients with non-proliferative diabetic retinopathy (NPDR) in a multi-ethnics Malaysian population. ·METHODS:We performed a case control study in which 150 patients with bilateral NPDR and CSME in either eye were compared to 150 patients with bilateral NPDR and no CSME in both eyes. CSME and NPDR were graded according to Early Treatment of Diabetic Retinopathy Study criteria. Student’s t-test, odds ratio and multiple logistic regression analysis were performed to analyze the duration of diabetes, body mass index (BMI), blood pressure(BP), total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), triglycerides (TG), fasting blood glucose (FBG), HbA1c, full blood count, serum creatinine and proteinuria between the two groups. ·RESULTS:Both groups were matched in terms of age, gender and ethnicity. Duration of diabetes, total serum cholesterol, serum LDL, FBG, HbA1c and serum creatinine were significantly higher in the CSME group (P <0.05). The hemoglobin, packed cell volume were significantly lower in the CSME group (P <0.05). There was no significant difference for serum HDL, TG, BMI, systolic and diastolic BP. Multiple logistic regression analysis showed that total serum cholesterol and HbA1c had significantly high odds of developing CSME. ·CONCLUSION:HbA1c and total cholesterol are the two most important risk factors associated with CSME in patients with NPDR.
文摘目的:探讨玻璃体切割术(pars plana vitrectomy,PPV)联合人工晶状体(intraocular lens,IOL)巩膜固定术治疗眼外伤的疗效。方法:系列病例回顾性分析。将马来西亚大学医学中心接受PPV联合IOL巩膜固定术的8例连续性病例纳入研究,其中1例患者双眼均受伤,共有9眼。对现阶段视力,手术技巧,并发症及术后疗效进行分析。结果:9眼中有8眼(89%)视力提高。术后主要并发症是眼压升高,无缝线破裂。结论:PPV联合IOL巩膜固定术对有眼外伤病史的患者有非常好的疗效。
