Dear Editor：Fortification programs are not established for nutrients like vitamin D among other nutrients in Iran.It is reported that approximately 80%of Iranians do not meet the estimated average requirement for cal...Dear Editor：Fortification programs are not established for nutrients like vitamin D among other nutrients in Iran.It is reported that approximately 80%of Iranians do not meet the estimated average requirement for calcium and vitamin D.The Iranian Multicenter Osteoporosis Study（IMOS）has shown that more than 80%of Iranians have vitamin D deficiency.However,currently,there is no data on vitamin D supplementation in elderly adults in Iran.We carried out a secondary analysis of a bigger population-based cross-sectional study,which was conducted among elderly men and women in the 6^th district of Tehran to determine the frequency of sarcopenia.展开更多
Systemic sclerosis is a rare chronic autoimmune disease with extensive microvascular injury, damage of endothelialcells, activation of immune responses, and progression of tissue fibrosis in the skin and various inter...Systemic sclerosis is a rare chronic autoimmune disease with extensive microvascular injury, damage of endothelialcells, activation of immune responses, and progression of tissue fibrosis in the skin and various internal organs.According to epidemiological data, women’s populations are more susceptible to systemic sclerosis than men. Untilnow, various therapeutic options are employed to manage the symptoms of the disease. Since stem cell-basedtreatments have developed as a novel approach to rescue from several autoimmune diseases, it seems that stemcells, especially mesenchymal stem cells as a powerful regenerative tool can also be advantageous for systemicsclerosis treatment via their remarkable properties including immunomodulatory and anti-fibrotic effects.Accordingly, we discuss the contemporary status and future perspectives of mesenchymal stem cell transplantationfor systemic sclerosis.展开更多
基金funded by TUMS and EMRS in order of their financial contributions
文摘Dear Editor：Fortification programs are not established for nutrients like vitamin D among other nutrients in Iran.It is reported that approximately 80%of Iranians do not meet the estimated average requirement for calcium and vitamin D.The Iranian Multicenter Osteoporosis Study（IMOS）has shown that more than 80%of Iranians have vitamin D deficiency.However,currently,there is no data on vitamin D supplementation in elderly adults in Iran.We carried out a secondary analysis of a bigger population-based cross-sectional study,which was conducted among elderly men and women in the 6^th district of Tehran to determine the frequency of sarcopenia.
文摘Systemic sclerosis is a rare chronic autoimmune disease with extensive microvascular injury, damage of endothelialcells, activation of immune responses, and progression of tissue fibrosis in the skin and various internal organs.According to epidemiological data, women’s populations are more susceptible to systemic sclerosis than men. Untilnow, various therapeutic options are employed to manage the symptoms of the disease. Since stem cell-basedtreatments have developed as a novel approach to rescue from several autoimmune diseases, it seems that stemcells, especially mesenchymal stem cells as a powerful regenerative tool can also be advantageous for systemicsclerosis treatment via their remarkable properties including immunomodulatory and anti-fibrotic effects.Accordingly, we discuss the contemporary status and future perspectives of mesenchymal stem cell transplantationfor systemic sclerosis.
