Systemic infammation is a recognized feature in chronic kidney disease (CKD). The role of systemic infammation in the pathogenesis of vascular calcifcation was recently settled. FGF23 was recently accused as a direc...Systemic infammation is a recognized feature in chronic kidney disease (CKD). The role of systemic infammation in the pathogenesis of vascular calcifcation was recently settled. FGF23 was recently accused as a direct stimulus of systemic inflammation. This finding explains the strong association of FGF23 to vascular calcifcation and increased mortality among CKD.展开更多
文摘Systemic infammation is a recognized feature in chronic kidney disease (CKD). The role of systemic infammation in the pathogenesis of vascular calcifcation was recently settled. FGF23 was recently accused as a direct stimulus of systemic inflammation. This finding explains the strong association of FGF23 to vascular calcifcation and increased mortality among CKD.