Glioblastoma(GBM)is extremely aggressive and essentially incurable.Its malignancy is characterized by vigorous microvascular proliferations.Recent evidence has shown that tumor cells display the ability to drive blood...Glioblastoma(GBM)is extremely aggressive and essentially incurable.Its malignancy is characterized by vigorous microvascular proliferations.Recent evidence has shown that tumor cells display the ability to drive blood-perfused vasculogenic mimicry(VM),an alternative microvascular circulation independent of endothelial cell angiogenesis.However,molecular mechanisms underlying this vascular展开更多
文摘Glioblastoma(GBM)is extremely aggressive and essentially incurable.Its malignancy is characterized by vigorous microvascular proliferations.Recent evidence has shown that tumor cells display the ability to drive blood-perfused vasculogenic mimicry(VM),an alternative microvascular circulation independent of endothelial cell angiogenesis.However,molecular mechanisms underlying this vascular
