Objective:To identify the early predictors of severe envenomation in the southern region of Tunisia.Methods:It was a retrospective monocentric study including consecutive patients admitted to the emergency department ...Objective:To identify the early predictors of severe envenomation in the southern region of Tunisia.Methods:It was a retrospective monocentric study including consecutive patients admitted to the emergency department for snakebite envenomation.Snakebite envenomation was defined by a history of snakebite.Predictors of severe envenomation were determined by univariate and multivariate analyses.Results:Our sample consisted of 109 patients aged 30(20-44)years with a 1.1:1 sex-ratio(56 males and 53 females).During the 24-hour surveillance period,25 patients developed severe envenomation(22.9%).The in-hospital mortality rate was 4.6%(n=5).The independent predictors of severe snakebite envenomation were leucocyte count over 11550/mm3(OR:18.7,95%CI:3.3-107.8),creatine kinase over 155 IU/L(OR:6.16,95%CI:1.1-35.6),and/or tourniquet before arrival to the ED(OR:32.14,95%CI:3.5-295.9).Conclusions:This study emphasizes the importance of early evaluation of snakebite envenomation.Further studies are required to approve a severity scale proper to snakebite envenomation in Tunisia.展开更多
Acute intoxication with nicotine is possible to cause nonspecific clinical signs and may be serious and lead to the death. We report a rare and severe form of acute nicotine poisoning secondary to dermal absorption of...Acute intoxication with nicotine is possible to cause nonspecific clinical signs and may be serious and lead to the death. We report a rare and severe form of acute nicotine poisoning secondary to dermal absorption of tobacco.展开更多
文摘Objective:To identify the early predictors of severe envenomation in the southern region of Tunisia.Methods:It was a retrospective monocentric study including consecutive patients admitted to the emergency department for snakebite envenomation.Snakebite envenomation was defined by a history of snakebite.Predictors of severe envenomation were determined by univariate and multivariate analyses.Results:Our sample consisted of 109 patients aged 30(20-44)years with a 1.1:1 sex-ratio(56 males and 53 females).During the 24-hour surveillance period,25 patients developed severe envenomation(22.9%).The in-hospital mortality rate was 4.6%(n=5).The independent predictors of severe snakebite envenomation were leucocyte count over 11550/mm3(OR:18.7,95%CI:3.3-107.8),creatine kinase over 155 IU/L(OR:6.16,95%CI:1.1-35.6),and/or tourniquet before arrival to the ED(OR:32.14,95%CI:3.5-295.9).Conclusions:This study emphasizes the importance of early evaluation of snakebite envenomation.Further studies are required to approve a severity scale proper to snakebite envenomation in Tunisia.
文摘Acute intoxication with nicotine is possible to cause nonspecific clinical signs and may be serious and lead to the death. We report a rare and severe form of acute nicotine poisoning secondary to dermal absorption of tobacco.
