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Neuroprotective potential of cannabidiol:Molecular mechanisms and clinical implications
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作者 Srushti M.Tambe Suraj Mali +1 位作者 Purnima D.Amin mozaniel oliveira 《Journal of Integrative Medicine》 SCIE CAS CSCD 2023年第3期236-244,共9页
Cannabidiol(CBD),a nonpsychotropic phytocannabinoid that was once largely disregarded,is currently the subject of significant medicinal study.CBD is found in Cannabis sativa,and has a myriad of neuropharmacological im... Cannabidiol(CBD),a nonpsychotropic phytocannabinoid that was once largely disregarded,is currently the subject of significant medicinal study.CBD is found in Cannabis sativa,and has a myriad of neuropharmacological impacts on the central nervous system,including the capacity to reduce neuroinflammation,protein misfolding and oxidative stress.On the other hand,it is well established that CBD generates its biological effects without exerting a large amount of intrinsic activity upon cannabinoid receptors.Because of this,CBD does not produce undesirable psychotropic effects that are typical of marijuana derivatives.Nonetheless,CBD displays the exceptional potential to become a supplementary medicine in various neurological diseases.Curently,many clinical trials are being conducted to investigate this possibility.This review focuses on the therapeutic effects of CBD in managing neurological disorders like Alzheimer's disease,Parkinson's disease and epilepsy.Overall,this review aims to build a stronger understanding of CBD and provide guidance for future fundamental scientific and clinical investigations,opening a new therapeutic window for neuroprotection. 展开更多
关键词 Cannabis sativa CANNABIDIOL Natural products Bioactive compounds Anti-neurodegenerative diseases
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