With continuous evolution in software industry, security is becoming very important in software projects. However, in many development methodologies, security is thought to be added in the project at later stages of t...With continuous evolution in software industry, security is becoming very important in software projects. However, in many development methodologies, security is thought to be added in the project at later stages of the development lifecycle. There are also many proposed methodologies where the security measures are considered at requirement engineering stage of the development lifecycle, but many of them still do not seem adequate for applicability due to the reason that these approaches do not provide sufficient support for mapping the security requirements to the later stages of development. So, we are in need of a software requirement engineering approach, which is not only helpful in security requirement specification at requirement engineering stage but also provides support for using the specified security requirements at later stages of development. To meet this requirement, we introduce a new method Secure and Traceable Requirement Engineering Process (STREP). This method also helps the non-security-expert requirement engineers to specify requirements in such a way that the specified requirements can be used to derive security related test cases. STREP method not only deals with security issues of the system at requirement engineering stage, but also makes the security requirements more traceable to be used at later stages of development lifecycle, and as a result, secure systems are produced that are also usable as the customer wishes.展开更多
Host-guest inclusion complexes have been extensively studied for drug delivery applications.The host molecule,typically cyclodextrin,creates a cavity,in which the guest molecule,such as a drug,can be encapsulated.This...Host-guest inclusion complexes have been extensively studied for drug delivery applications.The host molecule,typically cyclodextrin,creates a cavity,in which the guest molecule,such as a drug,can be encapsulated.This encapsulation can protect the drug from degradation,improve its solubility and stability,and enhance its bioavailability.Moreover,host-guest inclusion complexes can facilitate targeted drug delivery by selectively releasing drugs at the site of action.Various techniques,such as covalent bonding,non-covalent interactions,and self-assembly have been used to form these complexes.Host-guest inclusion complexes have shown great potential for improving the efficacy and safety of drug delivery systems.This mini review summarizes the application and recent progress of the cyclodextrin-based host-guest inclusion complex,highlighting the enhanced physicochemical and biopharmaceutical application of pharmaceutical drugs via formulation of its inclusion complex.展开更多
文摘With continuous evolution in software industry, security is becoming very important in software projects. However, in many development methodologies, security is thought to be added in the project at later stages of the development lifecycle. There are also many proposed methodologies where the security measures are considered at requirement engineering stage of the development lifecycle, but many of them still do not seem adequate for applicability due to the reason that these approaches do not provide sufficient support for mapping the security requirements to the later stages of development. So, we are in need of a software requirement engineering approach, which is not only helpful in security requirement specification at requirement engineering stage but also provides support for using the specified security requirements at later stages of development. To meet this requirement, we introduce a new method Secure and Traceable Requirement Engineering Process (STREP). This method also helps the non-security-expert requirement engineers to specify requirements in such a way that the specified requirements can be used to derive security related test cases. STREP method not only deals with security issues of the system at requirement engineering stage, but also makes the security requirements more traceable to be used at later stages of development lifecycle, and as a result, secure systems are produced that are also usable as the customer wishes.
基金supported by the Guangdong Postdoctoral Start-up Fund,China(No.Q0301-082)the High-level University Construction Fund of Guangdong Province,China(Nos.02-412-2202-2123,02-410-2206298,02-412-2302-2122xM)+1 种基金the Fund from He Guangzhou Science and Technology Bureau,China(No.202201010378)the Open Project of State Key Laboratory of Respiratory Disease,China(No.SKLRD-OP-202409).
文摘Host-guest inclusion complexes have been extensively studied for drug delivery applications.The host molecule,typically cyclodextrin,creates a cavity,in which the guest molecule,such as a drug,can be encapsulated.This encapsulation can protect the drug from degradation,improve its solubility and stability,and enhance its bioavailability.Moreover,host-guest inclusion complexes can facilitate targeted drug delivery by selectively releasing drugs at the site of action.Various techniques,such as covalent bonding,non-covalent interactions,and self-assembly have been used to form these complexes.Host-guest inclusion complexes have shown great potential for improving the efficacy and safety of drug delivery systems.This mini review summarizes the application and recent progress of the cyclodextrin-based host-guest inclusion complex,highlighting the enhanced physicochemical and biopharmaceutical application of pharmaceutical drugs via formulation of its inclusion complex.
