Recent progress in the research on using CuSbS_(2) and its derivative CuPbSbS_(3) as absorbers in case of photovoltaic devices

Thin-film solar cells show considerable application potential as alternative photovoltaic technologies.Cuprous antimony chalcogen materials and their derivatives,represented as CuSbS_(2) and CuPbSbS_(3),respectively,exhibit the advantages of low cost,massive elemental abundance,stability,and good photoelectric properties,including a suitable bandgap and large optical absorption coefficient.These advantages demonstrate that they can be used as light absorbers in photovoltaic applications.In this study,we review the major properties,fabrication methods,and recent progress of the performance of the devices containing CuSbS_(2) and CuPbSbS_(3).Furthermore,the limitations and future development prospects with respect to the CuSbS_(2) and CuPbSbS_(3) solar cells are discussed.

Broadly neutralizing antibodies derived from the earliest COVID-19 convalescents protect mice from SARS-CoV-2 variants challenge

Coronavirus disease 2019(COviD-19)was first reported three years ago,when a group of individuals were infected with the original SARS-CoV-2 strain,based on which vaccines were developed.Here,we develop six human monoclonal antibodies(mAbs)from two elite convalescents in Wuhan and show that these mAbs recognize diverse epitopes on the receptor binding domain(RBD)and can inhibit the infection of SARS-CoV-2 original strain and variants of concern(VOCs)to varying degrees,including Omicron strains XBB and XBB.

Genome-wide characterization of alternative splicing in blood cells of COVID-19 and respiratory infections of relevance

Dear Editor,Alternative splicing of eukaryotic transcripts refers to the posttranscriptional process in which the coding regions(exons)of a precursor transcript are joined in different combinations through the removal or retention of non-coding intervening sequences(introns)to produce distinct mature messenger RNA(mRNA)transcripts and further generate one or more mature mRNAs(Lee and Rio,2015).Alternative splicing is revealed dysregulation in infectious diseases.Many pathogens hijack the splicing mechanism of host cells to complete their replications,accompanied by dysregulated innate immune response or cell damage,leading to the changes of alternative splicing landscape in host cells(Ashraf et al.,2019;Tomezsko et al.,2020;Kremsdorf et al.,2021).The regulation mechanism of alternative splicing by viral pathogens,such as hepatitis B virus(Duriez et al.,2017),human immunodeficiency virus 1(Tomezsko et al.,2020),Zika virus(Bonenfant et al.,2020)and enterovirus 71(Li et al.,2020),have been explored.