The purpose of our study is to evaluate aggravation of arrhythmia induced byantiarrhythmic drugs during electrophysiologic testing In 266 tests, patients with arrhythmia weretreated with quinidine, procainamide, mexil...The purpose of our study is to evaluate aggravation of arrhythmia induced byantiarrhythmic drugs during electrophysiologic testing In 266 tests, patients with arrhythmia weretreated with quinidine, procainamide, mexiletine amicdarone, locainide pirmenol flacainide andnorpace and the results were analysed. Aggravation of arrhythmia induced by antiarrhythmic drugswas common, involving almost all antiarrhythmic drugs The incidence of aggravation was 21. 8%.There was no definite relationship between arrhythrnic aggravation and underlying heart diseases. Inno circumstances were blood levels in toxic range at the time of arrhythmic aggravation. Combinedwith antiarrhythmic drugs Ia+Ib (?) the incidence of aggravation of arrhythmia. Greatly wid-ened QRS might he a due to recognizing the danger of quinidine-induced arrhythmic aggravation.展开更多
文摘The purpose of our study is to evaluate aggravation of arrhythmia induced byantiarrhythmic drugs during electrophysiologic testing In 266 tests, patients with arrhythmia weretreated with quinidine, procainamide, mexiletine amicdarone, locainide pirmenol flacainide andnorpace and the results were analysed. Aggravation of arrhythmia induced by antiarrhythmic drugswas common, involving almost all antiarrhythmic drugs The incidence of aggravation was 21. 8%.There was no definite relationship between arrhythrnic aggravation and underlying heart diseases. Inno circumstances were blood levels in toxic range at the time of arrhythmic aggravation. Combinedwith antiarrhythmic drugs Ia+Ib (?) the incidence of aggravation of arrhythmia. Greatly wid-ened QRS might he a due to recognizing the danger of quinidine-induced arrhythmic aggravation.
