Present studies on the coupling relationship and hydrology mechanism between basin ecosystem and hydrological process has become an international research frontier in hydrology. This paper investigates this coupling r...Present studies on the coupling relationship and hydrology mechanism between basin ecosystem and hydrological process has become an international research frontier in hydrology. This paper investigates this coupling relationship, and also summarizes research and presents a method of combining isotopic technology with hydro-chemical methods, for the study of eco-hydrological process and function in different landscape zones. We then examine research trends for future direction and development of this field.展开更多
In this paper,we systematically investigated the structural and magnetic properties of CrTe by combining particle swarm optimization algorithm and first-principles calculations.By considering the electronic correlatio...In this paper,we systematically investigated the structural and magnetic properties of CrTe by combining particle swarm optimization algorithm and first-principles calculations.By considering the electronic correlation effect,we predicted the ground-state structure of CrTe to be NiAs-type(space group P63/mmc)structure at ambient pressure,consistent with the experimental observation.Moreover,we found two extra meta-stable Cmca and R3m structures which have negative formation enthalpy and stable phonon dispersion at ambient pressure.The Cmca structure is a layered antiferromagnetic metal.The cleaved energy of a single layer is 0.464 J/m^(2),indicating the possible synthesis of CrTe monolayer.The R3m structure is a ferromagnetic half-metal.When external pressure is applied,the ground-state structure of CrTe transitions from P63/mmc structure to R3m structure at a pressure of 34 GPa,then to Fm3m structure at 42 GPa.We thought these results help to motivate experimental studies of the CrTe compounds in the application of spintronics.展开更多
All organisms living in complex environments have evolved effective mechanisms of dynamic responses to extracellular stimuli.The immune system activates when damaged or injured cells release damage‐associated molecul...All organisms living in complex environments have evolved effective mechanisms of dynamic responses to extracellular stimuli.The immune system activates when damaged or injured cells release damage‐associated molecular patterns(DAMPs).In addition to well‐characterized DAMPs such as high‐mobility group box 1 and adenosine triphosphate,studies on new classes of DAMPs have emerged.Here,we review recent reports of a new class of isoprenoid‐derived DAMPs,including farnesyl pyrophosphate and geranylgeranyl pyrophosphate,both of which are pivotal metabolic inter-mediates of the mevalonate pathway.We also explore the roles of old and new DAMPs in autoimmune diseases that result from dysregulated inflammation.The findings highlight that understanding the functional mechanisms of DAMPs is important to enrich the DAMP family and decipher their immunoregulatory mechanisms to provide new therapeutics for the prevention and treatment of autoimmune diseases.展开更多
基金supported by the Projects Internation-al Science&Technology Cooperation Program of China(2012DFA20770)National Natural Science Foundation of China(41201043)+1 种基金Natural Science Foundation of Shanxi Province(2012021026-3)Science and Technology Major Projects of Shanxi Province(20121101011)
文摘Present studies on the coupling relationship and hydrology mechanism between basin ecosystem and hydrological process has become an international research frontier in hydrology. This paper investigates this coupling relationship, and also summarizes research and presents a method of combining isotopic technology with hydro-chemical methods, for the study of eco-hydrological process and function in different landscape zones. We then examine research trends for future direction and development of this field.
基金This work was supported by the National Natural Science Foundation of China(Nos.11904312 and 11904313),the Project of Hebei Educational Department,China(Nos.ZD2018015 and QN2018012),the Natural Science Foundation of Hebei Province of China(No.A2020203027),the Doctor Foundation Project of Yanshan University(No.BL19008),and the Scientific Research Foundation of the Higher Education of Hebei Province,China(No.BJ2020015).The numerical calculations in this paper have been done on the supercomputing system in the High Performance Computing Center of Yanshan University.
文摘In this paper,we systematically investigated the structural and magnetic properties of CrTe by combining particle swarm optimization algorithm and first-principles calculations.By considering the electronic correlation effect,we predicted the ground-state structure of CrTe to be NiAs-type(space group P63/mmc)structure at ambient pressure,consistent with the experimental observation.Moreover,we found two extra meta-stable Cmca and R3m structures which have negative formation enthalpy and stable phonon dispersion at ambient pressure.The Cmca structure is a layered antiferromagnetic metal.The cleaved energy of a single layer is 0.464 J/m^(2),indicating the possible synthesis of CrTe monolayer.The R3m structure is a ferromagnetic half-metal.When external pressure is applied,the ground-state structure of CrTe transitions from P63/mmc structure to R3m structure at a pressure of 34 GPa,then to Fm3m structure at 42 GPa.We thought these results help to motivate experimental studies of the CrTe compounds in the application of spintronics.
基金The authors acknowledge support from the Tsinghua University Spring Breeze Fund,Center for Life Sciences,and Institute for Immunology,Tsinghua University,and grants from the Ministry of Science and Technology of China(2021YFC2300500 and 2021YFC2302403)National Natural Science Foundation of China(32141004,81825010,81730043,and 81621002).
文摘All organisms living in complex environments have evolved effective mechanisms of dynamic responses to extracellular stimuli.The immune system activates when damaged or injured cells release damage‐associated molecular patterns(DAMPs).In addition to well‐characterized DAMPs such as high‐mobility group box 1 and adenosine triphosphate,studies on new classes of DAMPs have emerged.Here,we review recent reports of a new class of isoprenoid‐derived DAMPs,including farnesyl pyrophosphate and geranylgeranyl pyrophosphate,both of which are pivotal metabolic inter-mediates of the mevalonate pathway.We also explore the roles of old and new DAMPs in autoimmune diseases that result from dysregulated inflammation.The findings highlight that understanding the functional mechanisms of DAMPs is important to enrich the DAMP family and decipher their immunoregulatory mechanisms to provide new therapeutics for the prevention and treatment of autoimmune diseases.
