Alcoholic liver disease(ALD)encompasses liver damage caused by chronic,excessive alcohol consumption.It manifests initially as marked hepatocellular steatosis and can progress to steatohepatitis,liver fibrosis,and cir...Alcoholic liver disease(ALD)encompasses liver damage caused by chronic,excessive alcohol consumption.It manifests initially as marked hepatocellular steatosis and can progress to steatohepatitis,liver fibrosis,and cirrhosis.With China’s rapid economic growth,coupled with a complex social background and the influence of a deleterious wine culture,the number of patients with ALD in China has increased significantly;the disease has become a social and health problem that cannot be ignored.In this review,we briefly described the social factors affecting ALD in China and elaborated on differences between alcoholic and other liver diseases in terms of complications(e.g.,cirrhosis,upper gastrointestinal bleeding,hepatic encephalopathy,hepatocellular carcinoma,addiction,and other extrahepatic diseases).We also emphasized that ALD was more dangerous and difficult to treat than other liver diseases due to its complications,and that precise and effective treatment measures were lacking.In addition,we considered new ideas and treatment methods that may be generated in the future.展开更多
基金supported by Science and Technology Department of National Administration of Traditional Chinese Medicine-Administration of Traditional Chinese Medicine of Zhejiang Province Jointly Established Science and Technology Plan Project,Project No.GZY-ZJ-KJ-24071.
文摘Alcoholic liver disease(ALD)encompasses liver damage caused by chronic,excessive alcohol consumption.It manifests initially as marked hepatocellular steatosis and can progress to steatohepatitis,liver fibrosis,and cirrhosis.With China’s rapid economic growth,coupled with a complex social background and the influence of a deleterious wine culture,the number of patients with ALD in China has increased significantly;the disease has become a social and health problem that cannot be ignored.In this review,we briefly described the social factors affecting ALD in China and elaborated on differences between alcoholic and other liver diseases in terms of complications(e.g.,cirrhosis,upper gastrointestinal bleeding,hepatic encephalopathy,hepatocellular carcinoma,addiction,and other extrahepatic diseases).We also emphasized that ALD was more dangerous and difficult to treat than other liver diseases due to its complications,and that precise and effective treatment measures were lacking.In addition,we considered new ideas and treatment methods that may be generated in the future.
