Sclerosing mediastinitis is a very rare benign disorder characterised by the d evelopment of dense fibrous tissue within the mediastinum. Affected patients are typically young adults with infant cases being uncommon e...Sclerosing mediastinitis is a very rare benign disorder characterised by the d evelopment of dense fibrous tissue within the mediastinum. Affected patients are typically young adults with infant cases being uncommon especially in areas wit hout endemic histoplasmosis. We report a Japanese boy with markedly elevated ser um inflammatory markers for more than 1 year in the absence of any clinical mani festations. 67Gascintigraphy demonstrated an accumulation in the mediastinal reg ion and an open biopsy revealed a hard fibrous mass in the anteriosuperior media stinum. Thus, a diagnosis of idiopathic sclerosing mediastinitis was made. Concl usion:To the best of our knowledge, this case is the youngest patient reported w ith this disorder. In patients with mediastinal mass lesions the diagnosis of sc lerosing mediastinitis should be considered as well as infectious, autoimmune or neoplastic disease even in children.展开更多
A patient with unilateral upper medial medullary infarction presented with contralateral paralysis of the pharyngeal constrictor muscle in association with lemniscal sensory loss, pyramidal insufficiency, and central ...A patient with unilateral upper medial medullary infarction presented with contralateral paralysis of the pharyngeal constrictor muscle in association with lemniscal sensory loss, pyramidal insufficiency, and central facial palsy on the same side. Individual differences in supranuclear control of the pharyngeal muscles may explain this rare occurrence. The combination of these signs is described as a syndrome of upper medial medullary lesion.展开更多
文摘Sclerosing mediastinitis is a very rare benign disorder characterised by the d evelopment of dense fibrous tissue within the mediastinum. Affected patients are typically young adults with infant cases being uncommon especially in areas wit hout endemic histoplasmosis. We report a Japanese boy with markedly elevated ser um inflammatory markers for more than 1 year in the absence of any clinical mani festations. 67Gascintigraphy demonstrated an accumulation in the mediastinal reg ion and an open biopsy revealed a hard fibrous mass in the anteriosuperior media stinum. Thus, a diagnosis of idiopathic sclerosing mediastinitis was made. Concl usion:To the best of our knowledge, this case is the youngest patient reported w ith this disorder. In patients with mediastinal mass lesions the diagnosis of sc lerosing mediastinitis should be considered as well as infectious, autoimmune or neoplastic disease even in children.
文摘A patient with unilateral upper medial medullary infarction presented with contralateral paralysis of the pharyngeal constrictor muscle in association with lemniscal sensory loss, pyramidal insufficiency, and central facial palsy on the same side. Individual differences in supranuclear control of the pharyngeal muscles may explain this rare occurrence. The combination of these signs is described as a syndrome of upper medial medullary lesion.
