The Bacteria Absorption-based Yolk-Shell Ni3P-Carbon @ Reduced Graphene Oxides for Lithium-Ion Batteries

Traditional carbon layer enwrapping active materials cannot easily realize perfect cladding.Therefore,it still cannot prevent the pulverization of active materials during the course of charging/discharging.In this paper,we utilize natural bacteria to absorb nickel acetate,the active materials Ni3P nanoparticles are well enwrapped,as a natural organisms surviving for billions of years,their cell walls have a perfect carbon structure,and the cell walls become carbon layer through high annealing temperature.Based on this,the yolk-shell Ni3P–carbon@reduced graphene oxides paper is prepared,through a proper annealing temperature,the Ni3P particles disperse in the inner surface or both ends,so the active materials were prevented from dissolving into the electrolyte,so it may keep from invalidity during charging/discharging.The electrochemical performances display that it has stable and high capacities as Li-ion batteries(LIBs)anode.Its capacity can keep 200 cycles without any decrease,and especially its rate performance exhibits an excellent peculiarity,with the current density increasing from 400 to 1000 mA g^(−1) every 200 mA g^(−1),its capacities decrease only 9.8%,2.9%and 6.4%,and its can recover the same capacity when the current density comes back to 200 mA g^(−1).It may be a fine choice for LIBs.

Review and prospect of immune checkpoint blockade therapy represented by PD-1/PD-L1 in the treatment of clear cell renal cell carcinoma

As a common tumor of the urinary system,the morbidity and mortality related to renal carcinoma,are increasing annually.Clear cell renal cell carcinoma(CCRCC)is the most common subtype of renal cell carcinoma,accounting for approximately 75%of the total number of patients with renal cell carcinoma.Currently,the clinical treatment of ccRCC involves targeted therapy,immunotherapy,and a combination of the two.In immunotherapy,PD-1/PD-L1 blocking of activated T cells to kill cancer cells is the most common treatment.However,as treatment progresses,some patients gradually develop resistance to immunotherapy.Meanwhile,other patients experience great side effects after immunotherapy,resulting in a survival status far lower than the expected survival rate.Based on these clinical problems,many researchers have been working on the improvement of tumor immunotherapy in recent years and have accumulated numerous research results.We hope to find a more suitable direction for future immunotherapy for ccRCC by combining these results and the latest research progress.

土壤-植物体系中硒生物有效性评价研究进展

硒是哺乳动物必需的微量营养元素.鉴于其缺乏和毒害剂量间范围狭窄,在作物硒生物强化及硒污染土壤修复过程中需对土壤硒的生物有效性进行准确评价.但由于土壤是一个多相非均质的复杂体系,土壤类型较多且土壤性质差异很大,迄今国内外尚没有一个普遍适用的土壤有效硒测定及其有效性的评价方法.因此,本文综述了国内外常用的测定土壤有效硒含量的化学浸提法(包括单一浸提及连续浸提法)和新兴的梯度薄膜扩散技术(DGT法)的优缺点及适用性,提出0.1 mol/L KH2PO4-K2HPO4浸提法作为土壤有效硒测定方法;讨论了运用化学浸提法测定结果、基于此计算获得的特征参数(土壤结合强度(IR值)和移动系数(MF值))、植物硒含量表征土壤硒生物有效性的可行性,旨在为土壤-植物体系中硒生物有效性的评价提供依据.

Effects of IAA and ABA on the Immature Peach Fruit Development Process

Peach(Prunus persica cv. Dajiubao) was chosen as a model to clarify the roles of IAA and ABA during the fruit ripening process. Seventy days after flowering(DAF), the fruits were treated with IAA and ABA(0.1 mmol·L-1 and 1 mmol·L-1, respectively) and with the IAA transporter inhibitor(NPA) and the ABA biosynthesis inhibitor(NDGA). IAA decreased the fruit ABA concentration, and increased ethylene concentration, leading to fruit(70 DAF) softening and coloration. NPA had the opposite effect. ABA decreased IAA and ethylene concentrations, leading to fruit hardness and lack of color. NDGA had similar effects as with IAA application. A q PCR analysis indicated that in immature fruits, the expression levels of ethylene biosynthesis and signaling genes(PpACS, PpACO, PpETR, PpERF2), anthocyanin biosynthesis genes(PpCHS, PpDFR, PpF3 H, PpUFGT), cell wall softening genes(PpEXP1, PpEXP2, PpPG2, PpPME), and auxin biosynthesis genes(PpPIN, PpTIR1) were upregulated by IAA application but were inhibited by NPA. In contrast, these ripening-related genes were downregulated by ABA application, but upregulated by NDGA. Generally, the immature fruit ripening process requires a high IAA concentration to generate a large amount of ethylene. ABA appeared to modulate ripening through interference not only with ethylene and cell wall related genes but also with auxin-related genes.

Materials design and sensing mechanism of novel calix[6]arene composite for sensitively detecting amine drugs

In order to improve the co nvenie nce and sensitivity of amphetamines drug testing and reduce the threat of drugs to humans,we have designed a QCM gas sensor to detect amine-containing drugs.The sensing material is designed based on the chemical nature of amine drugs.The sensing mechanism is derived from a reve rsible Schiff base interaction between the amino group of the drug and the carbonyl group of the novel calix[6]arene derivatives as well as the hydrogen bond interaction between amino group and hydroxyl.The new composite material was well characterized by different analytical techniques including 1 H nuclear magnetic resonance(1 H-NMR),fourier transform infrared spectroscopy(FT-IR),scanning electro nic microscopy(SEM),transmission electron microscope(TEM),Raman spectra,powder X-ray diffraction,etc.The sensing experiments were conducted by coating the composite onto quartz crystal microbalance(QCM)transducers.The experimental results indicated that the novel calixarene derivatives and their GO complexes based on the design have excellent selectivity,high sensitivity and repeatability toβ-phenylethylamine.

Optimal Gestational Weight Gain for Women with Gestational Diabetes Mellitus—China,2011–2021

Summary What is already known about this topic?Joint effects of gestational weight gain(GWG)and hyperglycemia on adverse pregnancy outcomes suggest that lower optimal GWG is optimal for women with gestational diabetes mellitus(GDM).However,there is still a lack of guidelines.What is added by this report?Optimal weekly GWG range after diagnosis of GDM for underweight,normal-weight,overweight,and obese women was 0.37–0.56 kg/week,0.26–0.48 kg/week,0.19–0.32 kg/week,and 0.12–0.23 kg/week,respectively.What are the implications for public health practice?The findings may be used to inform prenatal counseling regarding optimal gestational weight gain for women with gestational diabetes mellitus,and suggest the need for weight gain management.

Weekly Weight Gain in Women with Gestational Diabetes Mellitus and Neonatal Birth Weight - China, 2011–2021

What is already known about this topic?Elevated gestational weight gain(GWG)during pregnancy among women diagnosed with gestational diabetes mellitus(GDM)is correlated with an increased instance of large for gestational age(LGA)and macrosomia.However,it remains uncertain whether managing weekly GWG following a GDM diagnosis positively impacts fetal birth weight.What is added by this report?Our study found that GWG following GDM diagnosis correlates positively with the risk of LGA and macrosomia among all body mass index(BMI)subgroups,especially for overweight and obese women.What are the implications for public health practice?The results of this research highlight the importance of enforcing a more stringent regulation on GWG on a weekly basis for overweight and obese women diagnosed with GDM,particularly when considering neonatal growth.