Introduction:Fumonisins are a group of widespread mycotoxins mainly existing in staple foods.Their toxicological effects on humans cause worldwide public health threat.During 2015–2020,the 6th China Total Diet Study(...Introduction:Fumonisins are a group of widespread mycotoxins mainly existing in staple foods.Their toxicological effects on humans cause worldwide public health threat.During 2015–2020,the 6th China Total Diet Study(TDS)was conducted to study the dietary exposure to fumonisins in the Chinese adult population.Methods:Fumonisins were analyzed by LCMS/MS in 288 composite dietary samples collected from 24 provincial-level administrative divisions.After combining the national consumption data with analytical results,estimated daily intakes(EDIs)were assessed and compared with health-based guide values(HBGV).Results:In the 6th China TDS,the highest fumonisin B(FBs)levels were found in staple foods/cereals among the 12 food categories.EDI of FBs was 104.9 ng/kg of body weight(bw)/day at the upper bound accounting 5.25% of the provisional maximum tolerable daily intake set by Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives.Among the 12 food categories,cereals and cereal products were the greatest contributor to FB exposure at 95%.Conclusion:Although the estimated exposure to FBs in the 6th China TDS were well below the HBGV for FBs in general,it was 2 times higher than the exposure in the 5th China TDS.Furthermore,the exposure to FB3 has increased remarkable and is worth further attention in China.展开更多
基金supported by the National Key Research and Development Program of China(2017YFC1600304 and 2017YFC1600500)the National Natural Science Foundation of China(31801456 and 31871723)Chinese Academy of Medical Science Research Unit Program(No.2019-12M-5-024).
文摘Introduction:Fumonisins are a group of widespread mycotoxins mainly existing in staple foods.Their toxicological effects on humans cause worldwide public health threat.During 2015–2020,the 6th China Total Diet Study(TDS)was conducted to study the dietary exposure to fumonisins in the Chinese adult population.Methods:Fumonisins were analyzed by LCMS/MS in 288 composite dietary samples collected from 24 provincial-level administrative divisions.After combining the national consumption data with analytical results,estimated daily intakes(EDIs)were assessed and compared with health-based guide values(HBGV).Results:In the 6th China TDS,the highest fumonisin B(FBs)levels were found in staple foods/cereals among the 12 food categories.EDI of FBs was 104.9 ng/kg of body weight(bw)/day at the upper bound accounting 5.25% of the provisional maximum tolerable daily intake set by Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives.Among the 12 food categories,cereals and cereal products were the greatest contributor to FB exposure at 95%.Conclusion:Although the estimated exposure to FBs in the 6th China TDS were well below the HBGV for FBs in general,it was 2 times higher than the exposure in the 5th China TDS.Furthermore,the exposure to FB3 has increased remarkable and is worth further attention in China.
