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Recombinant adeno-associated virus 8 vector in gene therapy:Opportunities and challenges 被引量:1
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作者 Liyuan Zhao Zixuan Yang +7 位作者 Minhui Zheng Lei Shi Mengyun Gu Gang Liu Feng Miao Yan Chang Fanghua Huang naping tang 《Genes & Diseases》 SCIE CSCD 2024年第1期283-293,共11页
In recent years,significant breakthroughs have been made in the field of gene ther-apy.Adeno-associated virus(AAV)is one of the most promising gene therapy vectors and a powerful tool for delivering the gene of intere... In recent years,significant breakthroughs have been made in the field of gene ther-apy.Adeno-associated virus(AAV)is one of the most promising gene therapy vectors and a powerful tool for delivering the gene of interest.Among the AAV vectors,AAV serotype 8(AAv8)has attracted much attention for its efficient and stable gene transfection into specific tissues.Currently,recombinant AAv8 has been widely used in gene therapy research on a va-riety of diseases,including genetic diseases,cancers,autoimmune diseases,and viral diseases. 展开更多
关键词 AAV8 Adeno-associated virus Gene therapy PRIMATES
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