Objective： Of this study was to compare this multiple-field conformal technique to the AP-PA technique with re- spect to target volume coverage and dose to normal tissues. Methods： Seventeen patients with stages Ⅱ-...Objective： Of this study was to compare this multiple-field conformal technique to the AP-PA technique with re- spect to target volume coverage and dose to normal tissues. Methods： Seventeen patients with stages Ⅱ-Ⅲ denocarcinoma of the stomach were treated with adjuvant postoperative chemoradiotherapy presented to radiotherapy department in National Cancer Institute, Cairo in period between February 2009 to March 2010 using 3D conformal radiotherapy technique that consisted of a monoisocentric arrangement Employing 4-6 radiation fields. For each patient, a second radiotherapy treatment plan was generated utilizing AP-PA fields, the two techniques were then compared for target volume coverage and dose to normal tissues using dose volume histogram （DVH） analysis. Results： The planning target volume （PTV） was adequately covered in both （ 3D ＆ 2D ） plans, comparative DVHs for the right kidney, left kidney and spinal cord demonstrate lower radiation doses using the conformal technique especially for left kidney ＆ spinal cord, but the liver doses is higher but still well below liver tolerance. Conclusion： 3D conformal radiotherapy produced reduced radiation doses to the kidneys （especially left kidney ＆ spinal cord） compared to AP-PA techniques, with the potential to reduce treatment toxicity.展开更多
文摘Objective： Of this study was to compare this multiple-field conformal technique to the AP-PA technique with re- spect to target volume coverage and dose to normal tissues. Methods： Seventeen patients with stages Ⅱ-Ⅲ denocarcinoma of the stomach were treated with adjuvant postoperative chemoradiotherapy presented to radiotherapy department in National Cancer Institute, Cairo in period between February 2009 to March 2010 using 3D conformal radiotherapy technique that consisted of a monoisocentric arrangement Employing 4-6 radiation fields. For each patient, a second radiotherapy treatment plan was generated utilizing AP-PA fields, the two techniques were then compared for target volume coverage and dose to normal tissues using dose volume histogram （DVH） analysis. Results： The planning target volume （PTV） was adequately covered in both （ 3D ＆ 2D ） plans, comparative DVHs for the right kidney, left kidney and spinal cord demonstrate lower radiation doses using the conformal technique especially for left kidney ＆ spinal cord, but the liver doses is higher but still well below liver tolerance. Conclusion： 3D conformal radiotherapy produced reduced radiation doses to the kidneys （especially left kidney ＆ spinal cord） compared to AP-PA techniques, with the potential to reduce treatment toxicity.
