Circulating serum tenascin-C(an extracellular matrix glycoprotein) levels in patients with idiopathic dilated cardiomyopathy(IDC) were measured. Serum tenasc in-C levels were increased in proportion to the severity of...Circulating serum tenascin-C(an extracellular matrix glycoprotein) levels in patients with idiopathic dilated cardiomyopathy(IDC) were measured. Serum tenasc in-C levels were increased in proportion to the severity of left ventricular dy sfunction in patients with IDC. The associations of serum tenascin-C levels wit h serum troponin T and procollagen type III aminoterminal peptide levels suggest that increased levels of serum tenascin-C indicate ongoing replacement fibrosi s after myocardial damage in IDC.展开更多
文摘Circulating serum tenascin-C(an extracellular matrix glycoprotein) levels in patients with idiopathic dilated cardiomyopathy(IDC) were measured. Serum tenasc in-C levels were increased in proportion to the severity of left ventricular dy sfunction in patients with IDC. The associations of serum tenascin-C levels wit h serum troponin T and procollagen type III aminoterminal peptide levels suggest that increased levels of serum tenascin-C indicate ongoing replacement fibrosi s after myocardial damage in IDC.