Kikuchi-Fujimoto disease:A comprehensive review

Kikuchi-Fujimoto disease,a rare form of necrotizing lymphadenitis,is an uncommon,benign,self-limiting disorder of obscure etiology.It affects mostly young adults of both genders.Clinically,it presents with fever and lymphadenopathy of a firm to rubbery consistency frequently involving cervical lymph nodes while weight loss,splenomegaly,leucopenia,and elevated erythrocyte sedimentation rate feature in severely affected patients.Cutaneous involvement occurs in about 30%-40%of cases as facial erythema and nonspecific erythematous papules,plaques,acneiform or morbilliform lesions of great histologic heterogeneity.Both Kikuchi-Fujimoto disease and systemic lupus erythematosus share an obscure and complex relationship as systemic lupus erythematosus may occasionally precede,develop subsequently,or sometimes be associated concurrently with Kikuchi-Fujimoto disease.It is often mistaken for non-Hodgkin lymphoma while lupus lymphadenitis,cat-scratch disease,Sweet’s syndrome,Still’s disease,drug eruptions,infectious mononucleosis,and viral or tubercular lymphadenitis are other common differentials.Fine needle aspiration cytology mostly has features of nonspecific reactive lymphadenitis and immunohistochemistry studies usually show variable features of uncertain diagnostic value.Since its diagnosis is exclusively from histopathology,it needs to be evaluated more carefully;an early lymph node biopsy will obviate the need for unnecessary investigations and therapeutic trials.Its treatment with systemic corticosteroids,hydroxychloroquine,or antimicrobial agents mostly remains empirical.The article reviews clinicoepidemiological,diagnostic,and management aspects of KFD from the perspective of practicing clinicians.

Synthesis of nano crystalline spatulae of lead zirconate titanate (PbZr0.52Ti0.48O3)

A simple and effective method for the synthesis of nano-crystalline PZT spatulae has been re-ported near MPB via a new Solution-Ignition Synthesis route and has been characterized by FT-IR, XRD, TG/DTG/DTA and SEM techniques. X-ray line broadening and Scherrer formula show crystallite size to be^20 nm. Densities of nano-crystalline spatulae of PZT in pellet form made by using 2% PVA and without PVA have been found to be 5.35 and 7.51 gm/cm3 respec-tively compared to the theoretical value of 7.78 gm/cm3. Dielectric constants of 83 and 227 of these spatulae with dielectric loss 0.118 and 0.0609 at 1 MHz and a high resistivity value of 3.043 * 107 Ω cm for PZT pellets made without PVA suggest these nano-crystalline PZT spatu-lae to be the potential candidates for high fre-quency applications.

A novel design approach of charge plasma tunnel FET for radio frequency applications

In this paper, the impact of extra electron source(EES) and dual metal gate engineering on conventional charge plasma TFET(CP-TFET) have been done for improving DC and analog/RF parameters. CP-TFET structure is upgraded to double source CP-TFET(DS-CP-TFET) by placing an EES below the source/channel junction for enhancing the device performance in terms of driving current and RF figures of merit(FOMs). But, in spite of these pros, the approach is having cons of higher leakage current similar to MOSFET and negative conductance(inherent nature of TFET). Both the issues have been resolved in the double source dual gate CP-TFET(DS-DG-CP-TFET) by gate workfunction engineering and drain underlapping respectively. Additionally,for getting the optimum performance of DS-DG-CP-TFET, the device sensitivity has been investigated in terms of position of EES,length of drain electrode and workfunction of gate electrode 1(GE1).

Effect of westernization on oral health among college students of Udaipur City,India

Background:There is overwhelming evidence that periodontal disease and dental caries affect the majority of populations and that western culture and lifestyle may have a profound influence on oral health,especially in adults.The present study was performed to determine the effect of westernization on the oral health of college students of Udaipur City,Rajasthan.Methods:A descriptive cross-sectional study was conducted among students attending various professional and non-professional bachelor's degree colleges of Udaipur City,Rajasthan,India,from March 2013 to May 2013.Eight hundred students were selected based on a two-stage random sampling procedure.Westernization was assessed by a self-administered structured questionnaire.Periodontal status,dental caries status and malocclusion were assessed according to World Health Organization(WHO) criteria(1997).Statistical analysis was performed using Chi-square and Multivariate logistic regression.The confidence level and level of significance were set at 95% and 5%,respectively.Results:The present study suggested that adverse habits,listening to English music and preferring English food had a significant association with dental caries and periodontal diseases.Malocclusion also showed a significant relationship with consuming English food for snacks and desserts.Multivariate analysis revealed a significantly greater odds ratio(OR) for periodontal disease and dental caries among those who preferred English food for lunch.Conclusion:Based on the results of the present study,there is an association between westernization and oral health.

Physical and biochemical changes in ultra-rapid air chilled broiler muscle and quality of marinated chicken breast filets

The effect of ultra-rapid chilling in air at-20℃ over water-immersion chilling on broiler carcasses was investigated for physical and biochemical attributes.Forty-eight eviscerated carcasses were divided into two groups,one group were subjected to air chilling and other to water-immersion chilling,and samples were drawn at time periods of 1,3 and 24 h post-chill to analyze for pH,ratios of adenine:inosine nucleotide(R-values),expressible moisture,cook yield,tenderness and color.Ultra-rapid air chilled carcasses showed significant differences(P<0.05)in pH,expressible moisture and cook yield at chosen post-chill time intervals over the carcasses chilled using water-immersion technique.It was concluded that air chilled carcasses had higher pH and expressible moisture,but the R-values,and shear values did not show significant differences,and only slight difference in color of carcasses processed by the two chilling methods.In a separate experiment with 108 commercially processed carcasses,quality attributes of pre-rigor marinated breast filets were studied after subjecting the carcasses to air chilling and water-immersion chilling.Twelve filets from air and water chilled carcass aged for 1,3,and 24 h were tumble marinated for 25 min in a Sodium Tri Polyphosphate(STPP)and NaCl solution with different pick up levels of 10,15 and 20%.After measuring marinade absorption,filets were aged at 2℃ for 24 h.No differences were observed between the air and water chilling treatments in terms of marinade retention at different marinade target levels(10,15 and 20%)and time intervals(24,27 and 47 h)but cook yield of air chilled marinated fillet was higher.In conclusion,processors using further-processing operations that debone meat may find that AC to be more suitable alternative for cooling poultry carcasses because fillet color,marination yield,and tenderness were not affected,but cook yield was improved.

Assessing the bird guild patterns in heterogeneous land use types around Jammu,Jammu and Kashmir,India

Land-use sprawl in the Himalayas has caused the conversion of natural habitat into human-modified habitats,thus degrading ecosystem health.Adaptation of birds to changing physical environment can be well understood by analyzing their habitat preferences,and foraging dynamics explored to a limited extent in the Himalayan region,as yet.To achieve a comprehensive understanding of avian guild structure,we used multivariate statistical techniques to classify bird species according to their similarities in foraging patterns and habitat preferences.Observations based on habitat and diet affinities accounted for rich avian diversity with a total of 208 bird species(about 15%of country’s avifauna)recorded from six different sites during 1 year survey.Unweighted pair-group average cluster analysis performed on the families revealed ten feeding and fifteen habitat guilds among 63 bird families observed.Subtropical forests harbored more species followed by urban forests and agricultural landscapes.Insectivorous and omnivorous outnumbered other feeding guilds in the study area.Bird assemblages were richer in protected areas and semidisturbed landscapes and did not show significant variation between the seasons.Results of the study revealed that different functional groups of birds behaved differently,primarily induced by choice of food.The site heterogeneity favored avifaunal persistence by providing favorable foraging,roosting,and nesting opportunities to birds.Composition of avian guilds indicated level of intactness and ecological integrity of ecosystems studied.This outcome thus sets the background for long-term analysis of bird-habitat relationship and their foraging dynamics.The study has the relevance for decision-makers to integrate avian guild structure as an essential ingredient in formulating conservation strategies.

Defect elimination in green sand casting using simulation techniques:A case study

The Reynolds number of molten metal flowing mold cavity causes bulk turbulence and is the main cause of defects like shrinkage porosity and sand erosion.Machined housings with shrinkage porosity at critical bearing bores and surface made the casting useless.In old gating casting areas of perimeters 290mm and 264mm of transmission housing,Reynolds numbers were observed as 16307 and 13806,respectively using simulation software.Data were collected from experiments to change casting area perimeters from 785mm and 785mm along with the addition of overlap area.New Reynolds numbers at two locations were observed as 3705 and 3393,respectively.Molten metal pressure,velocity and temperature results were related for final shrinkage results of the components on full production.The purpose of the study is to reduce shrinkage and porosity defects in green sand casting part using MAGMAS simulation software.High outcome was the reduction of casting machining rejection in transmission housing casting from 5.8%0.7%with savings of approximately 0.13 million USD over the period of 14 months.Implications of this work include casting defects study and reduction in different grades and weight range.