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右美托咪啶对无线镇痛管理下老年胸腔镜患者术后镇痛及认知功能的影响 被引量:4
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作者 吴城 江能 +2 位作者 张军 路建 周红梅 《中国内镜杂志》 2020年第1期51-55,共5页
目的探讨右美托咪啶对无线镇痛管理下的老年胸腔镜患者术后镇痛效果与术后认知功能的影响。方法选取2017年1月-2018年6月该院行胸腔镜手术治疗的80例老年患者,按照随机数字法将患者随机分为右美托咪啶联合舒芬太尼D+S组(40例)和舒芬太尼... 目的探讨右美托咪啶对无线镇痛管理下的老年胸腔镜患者术后镇痛效果与术后认知功能的影响。方法选取2017年1月-2018年6月该院行胸腔镜手术治疗的80例老年患者,按照随机数字法将患者随机分为右美托咪啶联合舒芬太尼D+S组(40例)和舒芬太尼S组(对照组,40例),对照组(S组)为无线镇痛泵中予以舒芬太尼,D+S组在对照组基础上联合应用右美托咪啶,比较两组患者术前术后不同时点简易精神量表(MMSE)评分、术后疼痛视觉模拟评分(VAS)、外周血白细胞介素-1(IL-1)、白细胞介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)的表达水平以及不良反应情况。结果D+S组与S组患者术前当天、术后5和7 d MMSE评分比较,差异无统计学意义(P>0.05),术后1和3 d,D+S组MMSE评分明显高于S组(P<0.05);D+S组术后6和12 h疼痛VAS评分明显低于S组(P<0.05),术后24和48 h,D+S组和S组疼痛VAS评分比较,差异无统计学意义(P>0.05);术前当天、术后5和7 d,两组患者IL-1、IL-6和TNF-α表达水平比较,差异均无统计学意义(P>0.05),术后1和3 d,IL-1、TNF-α和IL-6表达水平比较,差异均有统计学意义(P<0.05);D+S组恶心发生率明显低于S组(P<0.05),心动过缓发生率则高于S组(P<0.05),但呕吐和尿潴留发生率比较,两组差异无统计学意义(P>0.05)。结论右美托咪啶可有效改善无线镇痛管理下老年胸腔镜患者术后早期疼痛和认知功能,同时降低术后炎性因子水平。 展开更多
关键词 无线镇痛管理 右美托咪啶 胸腔镜 老年患者 术后镇痛 认知功能
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Dehydration melting of amphibolite at 1.5 GPa and 800–950C:Implications for the Mesozoic potassium-rich adakite in the eastern North China Craton 被引量:1
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作者 Zhilin Ye Fang Wan +4 位作者 neng jiang Jingui Xu Yuanyun Wen Dawei Fan Wenge Zhou 《Geoscience Frontiers》 SCIE CAS CSCD 2021年第2期896-906,共11页
Mesozoic intermediate-felsic magmatic rocks in the eastern North China Craton commonly show geochemical similarity to adakites.However,the lack of direct constraints from partial melting experiments at high pressures ... Mesozoic intermediate-felsic magmatic rocks in the eastern North China Craton commonly show geochemical similarity to adakites.However,the lack of direct constraints from partial melting experiments at high pressures and temperatures fuels a debate over the origin of these rocks.In this work,we performed partial melting experiments at 1.5 GPa and 800–950℃on amphibolite samples collected from the vicinity of the Mesozoic potassium-rich adakitic rocks in the Zhangjiakou area,northern margin of the North China Craton.The experimental melts range from granitic to granodioritic compositions,with SiO_(2)=56.4–72.6 wt.%,Al_(2)O_(3)=16.1–19.3 wt.%,FeO^(*)=2.4–9.6 wt.%,MgO=0.3–2.0 wt.%,CaO=0.6–3.8 wt.%,Na_(2)O=4.7–5.3 wt.%,and K_(2)O=2.6–3.9 wt.%,which are in the ranges of the surrounding Mesozoic potassium-rich adakitic rocks,except for the higher Al_(2)O_(3)contents and the data point at 1.5 GPa and 800℃.Trace element compositions of the melts measured by LA-ICP-MS are rich in Sr(849–1067 ppm)and light rare earth elements(LREEs)and poor in Y(<10.4 ppm)and Yb(<0.88 ppm),and have high Sr/Y(102–221)and(La/Yb)n(27–41)ratios and strongly fractionated rare earth element(REE)patterns,whereas no obvious negative Eu anomalies are observed.The geochemical characteristics show overall similarity to the Mesozoic potassium-rich adakitic rocks in the area,especially adakites with low Mg#,again except for the data point at 1.5 GPa and 800℃.The results suggest that partial melting of amphibolite can produce potassium-rich adakitic rocks with low Mg#in the eastern North China Craton under the experimental conditions of 1.5 GPa and 850–950℃.The experimental restites consist of hornblende(Hbl)+plagioclase(Pl)+garnet(Grt)±clinopyroxene(Cpx),a mineral assemblage significantly different from that of the nearby Hannuoba mafic granulite xenoliths which consist of Cpx+orthopyroxene(Opx)+Pl±Grt.Chemically,the experimental restites contain higher Al_(2)O_(3)but lower MgO and CaO than the Hannuoba mafic granulite xenoliths.We therefore argue that the Hannuoba mafic granulite xenoliths cannot represent the direct products of partial melting of the experimental amphibolite. 展开更多
关键词 AMPHIBOLITE Partial melting Eastern North China Craton Potassium-rich adakitic rocks Hannuoba granulite xenoliths
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华北克拉通太古宙地壳生长的峰期 被引量:3
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作者 刘鹏 郭敬辉 +4 位作者 彭澎 Ross N.Mitchell 毛梦霞 姜能 翟明国 《Science Bulletin》 SCIE EI CAS CSCD 2022年第15期1553-1555,M0003,共4页
长期以来2.7~2.8 Ga被普遍接受为华北克拉通太古宙地壳生长的主峰期,与全球地壳生长同步,其主要依据是华北克拉通多数锆石的亏损地幔Hf模式年龄的峰值分布在2.7~2.8 Ga.然而Hf模式年龄受源区成分和地幔模式的选择以及源区不均一性等多... 长期以来2.7~2.8 Ga被普遍接受为华北克拉通太古宙地壳生长的主峰期,与全球地壳生长同步,其主要依据是华北克拉通多数锆石的亏损地幔Hf模式年龄的峰值分布在2.7~2.8 Ga.然而Hf模式年龄受源区成分和地幔模式的选择以及源区不均一性等多种因素影响,具体数值未必有确切地质含义.而全球公认的2.7 Ga地壳生长峰期并非依据模式年龄,而主要依据:以绿岩带为代表的巨量镁铁质岩浆活动峰期在2.7 Ga,由此引发的巨量长英质岩浆活动峰期在2.7 Ga,全球地幔亏损事件的峰期也在2.7 Ga.与此相对应,对于华北克拉通,以绿岩带为代表的巨量镁铁质岩浆活动峰期在2.5 Ga,由此引发的巨量长英质岩浆活动峰期也在2.5 Ga.因此,如不考虑不同构造背景保存偏差的影响,~2.5 Ga应被视作华北克拉通较为明确的地壳生长的主峰期. 展开更多
关键词 华北克拉通 绿岩带 太古宙 峰期 模式年龄 岩浆活动 地壳生长 不均一性
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Origin of the Low δ^(18)O Signals in Zircons from the Early Cretaceous A-Type Granites in Eastern China:Evidence from the Kulongshan Pluton
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作者 Wenbo Fan neng jiang +1 位作者 Mingguo Zhai Jun Hu 《Journal of Earth Science》 SCIE CAS CSCD 2021年第6期1415-1427,共13页
The origin of lowδ^(18)O signals in zircons from the Early Cretaceous A-type granites in eastern China has long been disputed.It is uncertain whether the^(18)O-depleted features were inherited from high-temperature h... The origin of lowδ^(18)O signals in zircons from the Early Cretaceous A-type granites in eastern China has long been disputed.It is uncertain whether the^(18)O-depleted features were inherited from high-temperature hydrothermal altered source rock or resulted from water-rock interaction after emplacement.In this paper,zircon oxygen isotopes in the~130 Ma Kulongshan A-type granites in the northern North China Craton are analyzed.The zircons could be subdivided into 5 types based on their luminescent intensity and internal structures in CL images.Theirδ^(18)O values also vary in different types and show negative correlation with U and Th contents and accompanying cumulativeα-decay doses,implying that theirδ^(18)O values may have been modified to various degrees by meteoric water-rock interaction after the accumulation of radiation damage.The idea is further confirmed by oxygen isotopic equilibrium calculation between co-existing mineral pairs.It is inferred that only the least-influenced zircons,with slightly elevatedδ^(18)O values than normal mantle,have preserved the magmatic oxygen isotopes.In combination with other evidences,it is proposed that the A-type granites are lower-crustal-derived,unnecessarily invoking a high-temperature hydrothermal altered source.The proposition is applicable to many other Cretaceous A-type granites that have similar zircon behaviors. 展开更多
关键词 A-type granite low-δ^(18)O zircon radiation damage magma derivation
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