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Charcot-Marie-Tooth hereditary neuropathy revealed after administration of docetaxel in advanced breast cancer
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作者 Hampig Raphael Kourie nicolas mavroudakis +1 位作者 Philippe Aftimos Martine Piccart 《World Journal of Clinical Oncology》 CAS 2017年第5期425-428,共4页
Charcot-Marie-Tooth (CMT) neuropathy is the most common hereditary cause of neuropathy.Diagnosis is usually not made during the childhood but in adolescence or late adulthood.It is reported in the literature that some... Charcot-Marie-Tooth (CMT) neuropathy is the most common hereditary cause of neuropathy.Diagnosis is usually not made during the childhood but in adolescence or late adulthood.It is reported in the literature that some neurotoxic chemotherapeutical agents can reveal an asymptomatic CMT IA hereditary neuropathy.To our knowledge,we report here the first case of CMT IA revealed in a 55-year-old woman after the administration of docetaxel/trastuzumab/pertuzumab for metastatic breast cancer.This case stresses again the necessity to obtain a complete personal and familial anamnesis and to perform a neurologic examination before the administration of neurotoxic chemotherapeutical agents to prevent the clinical expression of these hereditary neuropathies. 展开更多
关键词 CHARCOT-MARIE-TOOTH IA DOCETAXEL Breast cancer NEUROTOXICITY PERIPHERAL NEUROPATHY
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