Fungi are an understudied,biotechnologically valuable group of organisms.Due to the immense range of habitats that fungi inhabit,and the consequent need to compete against a diverse array of other fungi,bacteria,and a...Fungi are an understudied,biotechnologically valuable group of organisms.Due to the immense range of habitats that fungi inhabit,and the consequent need to compete against a diverse array of other fungi,bacteria,and animals,fungi have developed numerous survival mechanisms.The unique attributes of fungi thus herald great promise for their application in biotechnology and industry.Moreover,fungi can be grown with relative ease,making production at scale viable.The search for fungal biodiversity,and the construction of a living fungi collection,both have incredible economic potential in locating organisms with novel industrial uses that will lead to novel products.This manuscript reviews fifty ways in which fungi can potentially be utilized as biotechnology.We provide notes and examples for each potential exploitation and give examples from our own work and the work of other notable researchers.We also provide a flow chart that can be used to convince funding bodies of the importance of fungi for biotechnological research and as potential products.Fungi have provided the world with penicillin,lovastatin,and other globally significant medicines,and they remain an untapped resource with enormous industrial potential.展开更多
This is a continuation of a series focused on providing a stable platform for the taxonomy of phytopathogenic fungi and fungus-like organisms.This paper focuses on one family:Erysiphaceae and 24 phytopathogenic genera...This is a continuation of a series focused on providing a stable platform for the taxonomy of phytopathogenic fungi and fungus-like organisms.This paper focuses on one family:Erysiphaceae and 24 phytopathogenic genera:Armillaria,Barrio-psis,Cercospora,Cladosporium,Clinoconidium,Colletotrichum,Cylindrocladiella,Dothidotthia,,Fomitopsis,Ganoderma,Golovinomyces,Heterobasidium,Meliola,Mucor,Neoerysiphe,Nothophoma,Phellinus,Phytophthora,Pseudoseptoria,Pythium,Rhizopus,Stemphylium,Thyrostroma and Wojnowiciella.Each genus is provided with a taxonomic background,distribution,hosts,disease symptoms,and updated backbone trees.Species confirmed with pathogenicity studies are denoted when data are available.Six of the genera are updated from previous entries as many new species have been described.展开更多
This paper is the second in a series focused on providing a stable platform for the taxonomy of phytopathogenic fungi.It focuses on 25 phytopathogenic genera:Alternaria,Bipolaris,Boeremia,Botryosphaeria,Calonectria,Co...This paper is the second in a series focused on providing a stable platform for the taxonomy of phytopathogenic fungi.It focuses on 25 phytopathogenic genera:Alternaria,Bipolaris,Boeremia,Botryosphaeria,Calonectria,Coniella,Corticiaceae,Curvularia,Elsinoe,Entyloma,Erythricium,Fomitiporia,Fulviformes,Laetisaria,Limonomyces,Neofabraea,Neofusicoccum,Phaeoacremonium,Phellinotus,Phyllosticta,Plenodomus,Pseudopyricularia,Tilletia,Venturia and Waitea,using recent molecular data,up to date names and the latest taxonomic insights.For each genus a taxonomic background,diversity aspects,species identification and classification based on molecular phylogeny and recommended genetic markers are provided.In this study,varieties of the genus Boeremia have been elevated to species level.Botryosphaeria,Bipolaris,Curvularia,Neofusicoccum and Phyllosticta that were included in the One Stop Shop 1 paper are provided with updated entries,as many new species have been introduced to these genera.展开更多
It may be difficult to distinguish the cause of death in drowning cases without specific findings.The aim of this study was to explore the forensic value of thoracic postmortem computed tomography(PMCT)using routine i...It may be difficult to distinguish the cause of death in drowning cases without specific findings.The aim of this study was to explore the forensic value of thoracic postmortem computed tomography(PMCT)using routine images and three-dimensional(3D)image reconstructions.The imaging data of PMCT examinations of six drowning cadavers,aged 21-54years,were analyzed.Twelve victims of sudden death from coronary artery disease(CAD)were chosen as a control group.After 3D bilateral lung images were reconstructed using image processing software,an interactive medical image control system was used to measure and analyze parameters including lung volume,lung volume ratio,mean CT value of the whole lung,and lung CT value distribution curves.Lung volume and lung volume ratio were used to assess the shape changes of the lung.Lung CT value distribution curves showed the corresponding number of pixels of the different CT values in the lung image.Lung volume was not signifi-cantly larger in drowning cases(mean 2958cm^(3))than in controls(mean 2342cm^(3)).Lung vo-lume ratio values in the drowning group(mean 0.3156)were greater than those in the control group(mean 0.2763);(P=0.02).There was no significant difference between the drowning and control group in the mean CT value of the whole lung.There were differences between lung CT value distribution curves in drowning victims and controls,with drowning victims showing a single peak and CAD cases showing a bimodal distribution.Thoracic PMCT is help-ful for the forensic medical diagnosis of drowning.Lung volume ratio and lung CT value distri-bution are potential indicators to distinguish between drowning and CAD.展开更多
Postmortem imaging(PMI)technology known as virtual autopsy or virtopsy is regarded as a useful method of noninvasive or minimally invasive autopsy in forensic practice.Postmortem computed tomography is applicable to t...Postmortem imaging(PMI)technology known as virtual autopsy or virtopsy is regarded as a useful method of noninvasive or minimally invasive autopsy in forensic practice.Postmortem computed tomography is applicable to traumatic investigation,acute hemorrhage,pulmonary parenchyma disease,calcification(calculus,atherosclerosis),and gas accumulation.Postmortem magnetic resonance(PMMR)has been proven to have advantages in soft tissue identification.Cardiac death is one of the keys and difficult points in forensic practice.With the introduction and development of PMCT angiography and PMMR,it was proved to be a very promising tool in the investigation of cardiac death,including vascular cavities and ischemic myocardium.This article reviewed the applications of the latest PMI and its related technologies in forensic cardiac pathology,including advantages,limitations,and development prospects.展开更多
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences,Grant No.XDB31000000Naritsada Thongklang would like to thank Thailand research fund grants“Study of saprobic Agaricales in Thailand to find new industrial mushroom products”(Grant No.DBG6180015)+10 种基金Mae Fah Luang University grant“Optimal conditions for domestication and biological activities of selected species of Ganoderrma”(Grant No.621C1535)K.D.Hyde and Naritsada Thongklang would like to thanks to Thailand research fund grants“Domestication and bioactive evaluation of Thai Hymenopellis,Oudemansiella,Xerula and Volvariella species(basidiomycetes)”(Grant No.DBG6180033)K.D.Hyde thanks the financial support from the Visiting Professor grant at Chiang Mai University,Thailand and KIB.The authors acknowledge the contribution of M.M.Vasanthakumari,K.M.Manasa and P.Rajani,in various stages of preparation of the manuscript.Samantha C.Karunarathna thanks CAS President’s International Fellowship Initiative(PIFI)for funding his postdoctoral research(Number 2018PC0006)the National Science Foundation.Associate Professor R Jeewon thanks University of Mauritius for support.Binu C.Samarakoon offers her sincere gratitude to the“National Research Council of Thailand”(NRCT Grant No.256108A3070006)for the financial supportPeter E Mortimer would like to thank the National Science Foundation of China and the Chinese Academy of Sciences for financial support under the following Grants:41761144055,41771063,Y4ZK111B01M.Doilom would like to thank Chiang Mai University,the 5th batch of Postdoctoral Orientation Training Personnel in Yunnan Province and the 64th batch of China Postdoctoral Science Foundation.T.S.Suryanarayanan thanks the United States-India Educational Foundation(USIEF)New Delhi and the Fulbright Scholar Program(USA)for the award of a Fulbright-Nehru Senior Researcher grant to conduct research in the Department of Chemistry and Biochemistry,The Ohio State University,USA.Thanks to Research and Researchers for Industries Grant(PHD57I0015)for financial support to Boontiya Chuankid.Birthe Sandargo is grateful to the Deutsche Forschungsgemeinschaft(DFG)for a PhD grant.Clara Chepkirui is indebted to a PhD stipend from the German Academic Exchange Service(DAAD)and the Kenya National Council for Science and Technology(NACOSTI)Kevin D Hyde would also like to thank the National Research Council of Thailand grants Thailands’Fungal Diversity,Solving Problems and Creating Biotechnological Products(Grant No.61201321016)This work is partly supported by the Department of Biotechnology,Government of India,New Delhi(Chemical Ecology of the North East Region(NER)of India:A collaborative programme Linking NER and Bangalore ResearchersDBT-NER/Agri/24/2013)and Indian Council of Agricultural Research(ICAR-CAAST-Project F.No./NAHEP/CAAST/2018-19)Government of India,New Delhi.
文摘Fungi are an understudied,biotechnologically valuable group of organisms.Due to the immense range of habitats that fungi inhabit,and the consequent need to compete against a diverse array of other fungi,bacteria,and animals,fungi have developed numerous survival mechanisms.The unique attributes of fungi thus herald great promise for their application in biotechnology and industry.Moreover,fungi can be grown with relative ease,making production at scale viable.The search for fungal biodiversity,and the construction of a living fungi collection,both have incredible economic potential in locating organisms with novel industrial uses that will lead to novel products.This manuscript reviews fifty ways in which fungi can potentially be utilized as biotechnology.We provide notes and examples for each potential exploitation and give examples from our own work and the work of other notable researchers.We also provide a flow chart that can be used to convince funding bodies of the importance of fungi for biotechnological research and as potential products.Fungi have provided the world with penicillin,lovastatin,and other globally significant medicines,and they remain an untapped resource with enormous industrial potential.
基金National Natural Science Foundation of China(No.31972222,31560489)Program of Intro-ducing Talents of Discipline to Universities of China(111 Program,D20023)+3 种基金Talent project of Guizhou Science and Technology Coop-eration Platform([2017]5788-5 and[2019]5641)and Guizhou Sci-ence,Technology Department International Cooperation Basic project([2018]5806)Guizhou University cultivation project[2017]5788-33.Kevin D.Hyde would like to thank“the future of specialist fungi in a changing climate:baseline data for generalist and specialist fungi associated with ants,Rhododendron species and Dracaena species”(Grant No.DBG6080013),Thailand Research Fund(TRF)Grant no RDG6130001“Impact of climate change on fungal diversity and biogeography in the Greater Mekong Subregion”.Work of Viktor Papp was supported by the Ministry for Innovation and Technology within the framework of the Higher Education Institutional Excellence Program(NKFIH-1159-6/2019)in the scope of plant breeding and plant protection research of Szent István University.Sinang Honsanan would like to thank the National Natural Science Foundation of China for supporting the Project no.31950410548.Our thanks are due to the Research and Researchers for Industries Grant(PHD57I0015)for financial support to Boontiya Chuankid.Napalai Chaiwan would like to thank the Royal Golden Jubilee PhD Program under Thailand Research Fund(RGJ)The scholarship no.PHD60K0147the 5th batch of Postdoctoral Orientation Training Personnel in Yunnan Province(Grant no.:Y934283261)the 64th batch of China Postdoctoral Science Foundation(Grant no.:Y913082271).
文摘This is a continuation of a series focused on providing a stable platform for the taxonomy of phytopathogenic fungi and fungus-like organisms.This paper focuses on one family:Erysiphaceae and 24 phytopathogenic genera:Armillaria,Barrio-psis,Cercospora,Cladosporium,Clinoconidium,Colletotrichum,Cylindrocladiella,Dothidotthia,,Fomitopsis,Ganoderma,Golovinomyces,Heterobasidium,Meliola,Mucor,Neoerysiphe,Nothophoma,Phellinus,Phytophthora,Pseudoseptoria,Pythium,Rhizopus,Stemphylium,Thyrostroma and Wojnowiciella.Each genus is provided with a taxonomic background,distribution,hosts,disease symptoms,and updated backbone trees.Species confirmed with pathogenicity studies are denoted when data are available.Six of the genera are updated from previous entries as many new species have been described.
基金funded by the grants of the National Natural Science Foundation of China(NSFC Grant Nos.31670027,31460011 and 30870009)the National Research Council of Thailand grants Thailands’Fungal Diversity,Solving Problems and Creating Biotechnological Products(Grant No.61201321016)+11 种基金Taxonomy,Diversity,Phylogeny and Evolution of fungi in Capnodiales(Grant No.61215320024)"the future of specialist fungi in a changing climate:baseline data for generalist and specialist fungi associated with ants,Rhododendron species and Dracena species"(Grant No.DBG6080013)"Impact of climate change on fungal diversity and biogeography in the Greater Mekong Subregion"(RDG6130001)Mae Fah Luang University and University of Mauritius for research supportthe support from Biosystems and Integrative Sciences Institute(BioISI,FCT/UID/Multi/04046/2013)Associacao Nordesta for field support,Capes-SIU(008/13)and Fundacao de Amparo a Ciencia e Technologia de Pernambuco(FACEPE,APQ-0375-2.03/15)for financial supportthe Conselho Nacional de Desenvolvimento Cientifico e Technologico(CNPq)(307601/2015-3 and 312186/2016-9)for scholarshipsthe University of Queensland Development Fellowships(UQFEL1718905)support from the Department of the Environment and Energy under the Australian Biological Resources Study(Grant No.RG18-43)the Royal Golden Jubilee PhD program under Thailand Research Fund for a personal grant(RGJ scholarship no.PHD/0002/2560)the National Natural Science Foundation of China(Project ID:NSF31500017 to Huang Zhang)CAS President’s International Fellowship Initiative(PIFI)for funding his postdoctoral research(number 2019PC0008)the National Science Foundation of China and the Chinese Academy of Sciences for financial support under the following grants:41761144055,41771063 and Y4ZK111B01.
文摘This paper is the second in a series focused on providing a stable platform for the taxonomy of phytopathogenic fungi.It focuses on 25 phytopathogenic genera:Alternaria,Bipolaris,Boeremia,Botryosphaeria,Calonectria,Coniella,Corticiaceae,Curvularia,Elsinoe,Entyloma,Erythricium,Fomitiporia,Fulviformes,Laetisaria,Limonomyces,Neofabraea,Neofusicoccum,Phaeoacremonium,Phellinotus,Phyllosticta,Plenodomus,Pseudopyricularia,Tilletia,Venturia and Waitea,using recent molecular data,up to date names and the latest taxonomic insights.For each genus a taxonomic background,diversity aspects,species identification and classification based on molecular phylogeny and recommended genetic markers are provided.In this study,varieties of the genus Boeremia have been elevated to species level.Botryosphaeria,Bipolaris,Curvularia,Neofusicoccum and Phyllosticta that were included in the One Stop Shop 1 paper are provided with updated entries,as many new species have been introduced to these genera.
基金supported by grants from the National Key R&D Program of China[grant number 2016YFC0800702]the Science and Technology Committee of Shanghai Municipality[grant number 17DZ2200700]+3 种基金the National Natural Science Found of China[grant number 81571851]the Shanghai Key Laboratory of Crime Scene Evidence[grant number 2017XCWZK06]the Shanghai Key Laboratory of Forensic Medicine[grant number 17DZ2273200]and the Shanghai Forensic Service Platform[grant number 16DZ2290900].
文摘It may be difficult to distinguish the cause of death in drowning cases without specific findings.The aim of this study was to explore the forensic value of thoracic postmortem computed tomography(PMCT)using routine images and three-dimensional(3D)image reconstructions.The imaging data of PMCT examinations of six drowning cadavers,aged 21-54years,were analyzed.Twelve victims of sudden death from coronary artery disease(CAD)were chosen as a control group.After 3D bilateral lung images were reconstructed using image processing software,an interactive medical image control system was used to measure and analyze parameters including lung volume,lung volume ratio,mean CT value of the whole lung,and lung CT value distribution curves.Lung volume and lung volume ratio were used to assess the shape changes of the lung.Lung CT value distribution curves showed the corresponding number of pixels of the different CT values in the lung image.Lung volume was not signifi-cantly larger in drowning cases(mean 2958cm^(3))than in controls(mean 2342cm^(3)).Lung vo-lume ratio values in the drowning group(mean 0.3156)were greater than those in the control group(mean 0.2763);(P=0.02).There was no significant difference between the drowning and control group in the mean CT value of the whole lung.There were differences between lung CT value distribution curves in drowning victims and controls,with drowning victims showing a single peak and CAD cases showing a bimodal distribution.Thoracic PMCT is help-ful for the forensic medical diagnosis of drowning.Lung volume ratio and lung CT value distri-bution are potential indicators to distinguish between drowning and CAD.
基金By grants from the National Key Research and Development Program of China(no.2022YFC3302002)the Council of National Science Foundation of China(grant number 82171872)+4 种基金the Council of National Science Foundation of Shanghai(grant number 21ZR1464600)Key Laboratory of judicial expertise of Ministry of Justice and Shanghai Key Laboratory of Forensic Medicine(grant number 21DZ2270800)Shanghai Forensic Service Platform(grant number 19DZ2292700)Central Research Institute Public Project(grant numbers2020Z‑4,2021G‑4)Shanghai Key Laboratory of Forensic Medicine,Key Lab of Forensic Science,Ministry of Justice(grant number KF202120).
文摘Postmortem imaging(PMI)technology known as virtual autopsy or virtopsy is regarded as a useful method of noninvasive or minimally invasive autopsy in forensic practice.Postmortem computed tomography is applicable to traumatic investigation,acute hemorrhage,pulmonary parenchyma disease,calcification(calculus,atherosclerosis),and gas accumulation.Postmortem magnetic resonance(PMMR)has been proven to have advantages in soft tissue identification.Cardiac death is one of the keys and difficult points in forensic practice.With the introduction and development of PMCT angiography and PMMR,it was proved to be a very promising tool in the investigation of cardiac death,including vascular cavities and ischemic myocardium.This article reviewed the applications of the latest PMI and its related technologies in forensic cardiac pathology,including advantages,limitations,and development prospects.