^(11)C-methionine (MET) and ^(18)F-fluorothymidine (FLT) PET in patients withnewly diagnosed glioma

Eur J Nucl Med Mol Imaging. 2008 Jun 10.PURPOSE: The purpose of this prospective study was to clarify the individual and combined role of L: -methyl-(11)C-methionine-positron emission tomography (MET-PET) and 3' -deoxy-3' -[(18)F]fluorothymidine (FLT)-PET in tumor detection,noninvasive grad-ing, and assessment of the cellular proliferation rate in newly diagnosed histologically verified gliomas of different grades. MATERI-

细胞源性天花冻干减毒活疫苗“LC16-KAKETSUKEN”:上市后符合良好药品临床试验规范的安全性和有效性的监测研究

在日本,天花疫苗LC16m8（LC16-KAKET-SUKEN）于2002年3月重新启动生产,决定仍作为国家储备用疫苗。将减毒牛痘病毒株LC16m8通过细胞培养,制备了天花冻干减毒活疫苗LC16-KAKETSUKEN,用于上市后的监测研究。此研究聚焦于初次接种者和再次接种者的对照比较,研究符合良好药品临床试验规范。对日本陆上自卫队268人（261名男性和7名女性）接种了LC16-KAKETSUKEN,此后对不良反应和有效性进行了评价。268名疫苗接种者中,下列的接种者发生了不良反应（无严重不良反应）：