OBJECTIVE: To estimate whether maternal weight changes between pregnancies i nf luence the risk for small for gestational age (SGA) births. METHODS: SGA cases ( n = 8,062) below the tenth percentile birth weight for g...OBJECTIVE: To estimate whether maternal weight changes between pregnancies i nf luence the risk for small for gestational age (SGA) births. METHODS: SGA cases ( n = 8,062) below the tenth percentile birth weight for gestational age were sele cted from liveborn singletons born of Missouri residents during 1989-1997. Norm al weight controls (n = 8,062) were selected according to birth year. The risk o f SGA from interpregnancy body mass index (BMI) change and other maternal factor s was estimated using logistic regression analysis. RESULTS: An increase in BMI between pregnancies decreased SGA risk (adjusted odds ratio = 0.8; 95%confidenc e interval 0.7, 1.0). Other risk factors were prior SGA (4.4; 4.0, 4.8), preecla mpsia/eclampsia (2.6; 2.1, 3.2), maternal cardiac disease (1.8; 1.1, 2.9), inade quate weight gain (1.9; 1.8, 2.2), and cigarette smoking (1.9; 1.7, 2.3 for 1-9 cigarettes per day; 2.5; 2.2, 2.8 for 10-19/d; and 2.8; 2.5, 3.3 for 20/d or m ore). CONCLUSION: Increase in interpregnancy BMI lowers SGA risk, but adequate w eight gain during pregnancy is more effective.展开更多
文摘OBJECTIVE: To estimate whether maternal weight changes between pregnancies i nf luence the risk for small for gestational age (SGA) births. METHODS: SGA cases ( n = 8,062) below the tenth percentile birth weight for gestational age were sele cted from liveborn singletons born of Missouri residents during 1989-1997. Norm al weight controls (n = 8,062) were selected according to birth year. The risk o f SGA from interpregnancy body mass index (BMI) change and other maternal factor s was estimated using logistic regression analysis. RESULTS: An increase in BMI between pregnancies decreased SGA risk (adjusted odds ratio = 0.8; 95%confidenc e interval 0.7, 1.0). Other risk factors were prior SGA (4.4; 4.0, 4.8), preecla mpsia/eclampsia (2.6; 2.1, 3.2), maternal cardiac disease (1.8; 1.1, 2.9), inade quate weight gain (1.9; 1.8, 2.2), and cigarette smoking (1.9; 1.7, 2.3 for 1-9 cigarettes per day; 2.5; 2.2, 2.8 for 10-19/d; and 2.8; 2.5, 3.3 for 20/d or m ore). CONCLUSION: Increase in interpregnancy BMI lowers SGA risk, but adequate w eight gain during pregnancy is more effective.
