小柴胡汤加减治疗下焦湿热型尿路感染63例

目的观察小柴胡汤加减治疗下焦湿热型尿路感染的临床疗效。方法将126例符合纳入标准的下焦湿热型尿路感染患者按照随机数字表法分为治疗组与对照组,各63例。对照组给予头孢克肟分散片治疗,治疗组给予头孢克肟分散片+小柴胡汤加减治疗。比较两组患者疗效、治疗前后中医证候积分、治疗后尿常规、不良反应。结果治疗组总有效率为98.4%,对照组总有效率为88.9%,治疗组疗效优于对照组(P<0.05)。治疗后,治疗组中医证候积分(1.87±0.95)分明显低于对照组的(3.03±0.04)分(P<0.05)。治疗组尿常规恢复正常率为98.4%,优于对照组的88.9%(P<0.05)。两组均未发生严重药物不良反应。结论小柴胡汤加减治疗下焦湿热型尿路感染临床疗效显著,值得临床推广和使用。

Synthesis and Spectroscopic Properties of Cyclotriphosphazenes Containing 6-(4-Hydroxyphenyl)-2,2'-bipyridine Side Groups

Two novel cyclotriphosphazene derivatives containing 6- （4-hydroxyphenyl）-2,2′-bipyridine （hopbp） side groups, N3 P3 （dobp） 2 （hopbp） 2 （ 1 ） and N3 P3 （dobp） （hopbp） 4 （2） （ dobp = 2,2′-dioxybiphenyl）, were synthesized and characterized. These compounds display strong fluorescent emission both in solution and in solid state. Their absorption and emission spectra are sensitive to proton： the addition of HBF4 to the methanol and dichloromethane solution（9： 1, volume ratio） of compound 1 led to a red-shift from 350 to 460 nm for the emission spectrum, and the process was also characterized by isosbestic points of absorption spectra at 267, 287 and 313 nm.

Research on the Anticorrosion Coating Under the Paved Layer for Highway Steel Box Bridge Deck

The corrosion of the anticorrosion coating and the defects of the asphalt concrete paved layer have been investigated on long-span steel box bridge decks. The anticorrosion coating lies in the midclle of two entirely different materials： a highway steel box bridge deck and a paved layer, which is used as anticorrosion and waterproof coating for the steel bridge deck. For our study, electrochemical corrosion and pull strength experiments have been selected for the investigation of the corrosion properties of inorganic zinc rich coating, epoxy zinc rich coating and arc sprayed zinc coating. The adhesive strength between the coatings and the panel, and the effect of the coating corrosion on the shear properties of the paved layers including cast asphalt, thermal asphalt mortar, epoxy asphalt and modified asphalt con- crete have been investigated. The results show that the adhesive strength between the coatings and the bridge panel is controlled by the method of pre-processing rust removal. Coating by sandblasting has stronger adhesive strength than coating by shot peening. The results also reveal that shear strength of the paved layer is affected by the corrosion product of zinc coating. The arc sprayed zinc coating has stronger shear strength than zinc rich coatings.

Association of chronic obstructive pulmonary disease with coronary artery disease

Background The relationship between chronic obstructive pulmonary disease （COPD） and coronary artery disease （CAD） remains largely unknown. This study aimed to explore the association of COPD with CAD, especially with multi- vessel disease （VD）. Methods The data of 354 patients who underwent multi-detector computed tomography （MDCT） for suspected CAD were analyzed. Luminal narrowing was defined as at least one lesion 50% or greater stenosis. The analysis of serum biochemistry profile and spirometrywere performed on all eligible patients, and the diagnosis of COPD was defined as the criteria of Global Initiative for Chronic Obstructive Lung Disease. Results Patients with CAD had a significantly higher complication of COPD than those without CAD （11.8% vs. 3.7%, P 〈0.001）. Comparing with patients without COPD, those with COPD were more likely to have multi-VD, proportion of smoking and high C-reactive protein （CRP） （P 〈0.001）. Multivariate Logistic regression analysis revealed that the multi-VD was significantly correlated with COPD （P=-0.012） and CRP （P=0.015）. Conclusions There was a high complication of COPD in patients with CAD, and COPD may be a critical risk factor for CAD, especially for multi-VD. CAD and COPD were closely associated and the interplay of systemic inflammation might in part explain the relationship between them.

Relationship between 6-minute walk test and pulmonary function test in stable chronic obstructive pulmonary disease with different severities

Background The relationship between the 6-minute walk test （6MWT） and pulmonary function test in stable chronic obstructive pulmonary disease （COPD） remains unclear. We evaluate the correlation of 6MWT and spirometric parameters in stable COPD with different severities. 6MWT data assessed included three variables： the 6-minute walk distance （6MWD）, 6-minute walk work （6MWORK）, and pulse oxygen desaturation rate （SPO2%）. Methods 6MWT and pulmonary function test were assessed for 150 stable COPD patients with different severities. Means and standard deviations were calculated for the variables of interest. Analysis of variance was performed to compare means. Correlation coefficients were calculated for 6MWT data with the spirometric parameters and dyspnea Borg scale. Multiple stepwise regression analysis was used to screen pulmonary function-related predictors of 6MWT data. Results The three variables of 6MWT all varied as the severities of the disease. The 6MWD and 6MWORK both correlated with some spirometric parameters （positive or negative correlation; the absolute value of r ranging from 0.34 to 0.67; P 〈0.05） in severe and very severe patients, and the SPO2% correlated with the dyspnea Borg scale in four severities （t= -0.33, -0.34, -0.39, -0.53 respectively; P 〈0.05）. The 6MWD was correlated with the 6MWORK in four severities （r=0.56, 0.57, 0.72, 0.81 respectively, P 〈0.05）, and neither of them correlated with the SPO2%. The percent of predicted forced expiratory volume in 1 second （FEV1% predicted） and residual volume to total lung capacity ratio （RV/TLC） were predictors of the 6MWD, and the maximum voluntary ventilation （MW） was the predictor of the 6MWORK. Conclusions 6MWT correlated with the spirometric parameters in severe and very severe COPD patients. 6MWT may be used to monitor changes of pulmonary function in these patients.