A novel strategy was developed to prepare the methacrylic gelatin-dopamine(GelMA-DA)/Ag nanoparticles(NPs)/graphene oxide(GO) composite hydrogels with good biocompatibility,mechanical properties,and antibacterial acti...A novel strategy was developed to prepare the methacrylic gelatin-dopamine(GelMA-DA)/Ag nanoparticles(NPs)/graphene oxide(GO) composite hydrogels with good biocompatibility,mechanical properties,and antibacterial activity.Mussel-inspired DA was utilized to modify the GelMA molecules,which imparts good adhesive performance to the hydrogels.GO,interfacial enhancer,not only improves mechanical properties of the hydrogels,but also provides anchor sites for loading Ag NPs through numerous oxygencontaining functional groups on the surface.The experimental results show that the GelMA/Ag NPs/GO hydrogels have good biocompatibility,and exhibit a swelling rate of 202±16%,the lap shear strength of 147±17 kPa,and compressive modulus of 136±53 kPa,in the case of the Ag NPs/GO content of 2 mg/mL.Antibacterial activity of the hydrogels against both gram-negative and gram-positive bacteria is dependent on the Ag NPs/GO content derived from the release of Ag^(+).Furthermore,the GelMA/Ag NPs/GO hydrogels possess good adhesive ability,which is resistant to highly twisted state when stuck on the surface of pigskin.These results demonstrate promising potential of the GelMA-DA/Ag NPs/GO hydrogels as wound dressings for biomedical applications in clinical and emergent treatment.展开更多
Along with the prosperous of magnetic coupled inductive power transfer( MCIPT) technology which is widely used in industrial applications such as electric vehicle charging,the topology of double D coils( DD coils) wit...Along with the prosperous of magnetic coupled inductive power transfer( MCIPT) technology which is widely used in industrial applications such as electric vehicle charging,the topology of double D coils( DD coils) with a spatial quadrature Q coil arises with great research interest. The Q coil, however, has been thoroughly studied by adding to the receiving side but seldom to the transmitting side. By using finite element simulation, this paper presents a preliminary study on the effectiveness of Q coil in the transmitting side,and its inner dimension is optimized for optimal compensating the misalignment between the transmitting and receiver sides. Simulation results show that the windings of the Q coil should be placed in the center of the aperture of the DD coils,and these results render a useful guidance for mechanical structural design and circuit controller design of MCIPT.展开更多
基金Funded by the National Key Research and Development(R&D) Program of China(No.2018YFB1105702)。
文摘A novel strategy was developed to prepare the methacrylic gelatin-dopamine(GelMA-DA)/Ag nanoparticles(NPs)/graphene oxide(GO) composite hydrogels with good biocompatibility,mechanical properties,and antibacterial activity.Mussel-inspired DA was utilized to modify the GelMA molecules,which imparts good adhesive performance to the hydrogels.GO,interfacial enhancer,not only improves mechanical properties of the hydrogels,but also provides anchor sites for loading Ag NPs through numerous oxygencontaining functional groups on the surface.The experimental results show that the GelMA/Ag NPs/GO hydrogels have good biocompatibility,and exhibit a swelling rate of 202±16%,the lap shear strength of 147±17 kPa,and compressive modulus of 136±53 kPa,in the case of the Ag NPs/GO content of 2 mg/mL.Antibacterial activity of the hydrogels against both gram-negative and gram-positive bacteria is dependent on the Ag NPs/GO content derived from the release of Ag^(+).Furthermore,the GelMA/Ag NPs/GO hydrogels possess good adhesive ability,which is resistant to highly twisted state when stuck on the surface of pigskin.These results demonstrate promising potential of the GelMA-DA/Ag NPs/GO hydrogels as wound dressings for biomedical applications in clinical and emergent treatment.
基金Sichuan International Exchange of Science and Technology Cooperation and Research Program,China(No.2015HH0010)
文摘Along with the prosperous of magnetic coupled inductive power transfer( MCIPT) technology which is widely used in industrial applications such as electric vehicle charging,the topology of double D coils( DD coils) with a spatial quadrature Q coil arises with great research interest. The Q coil, however, has been thoroughly studied by adding to the receiving side but seldom to the transmitting side. By using finite element simulation, this paper presents a preliminary study on the effectiveness of Q coil in the transmitting side,and its inner dimension is optimized for optimal compensating the misalignment between the transmitting and receiver sides. Simulation results show that the windings of the Q coil should be placed in the center of the aperture of the DD coils,and these results render a useful guidance for mechanical structural design and circuit controller design of MCIPT.
