Rising demand for islet transplantation will lead to severe donor shortage in the near future, especially in countries where cadaveric organ donation is scarc e. We undertook a successful transplantation of livingdo...Rising demand for islet transplantation will lead to severe donor shortage in the near future, especially in countries where cadaveric organ donation is scarc e. We undertook a successful transplantation of livingdonor islets for unstabl e diabetes. The recipient was a 27-yearold woman who had had brittle, insulin dependent diabetes mellitus for 12 years. The donor, who was a healthy 56-yea rold woman and mother of the recipient, underwent a distal pancreatectomy. Aft er isolation, 408 114 islet equivalents were transplanted immediately. The trans plants functioned immediately and the recipient became insulinindependent 22 d ays after the operation. The donor had no complications and both women showed he althy glucose tolerance. Transplantation of livingdonor islets from the distal pancreas can be sufficient to reverse brittle diabetes.展开更多
文摘Rising demand for islet transplantation will lead to severe donor shortage in the near future, especially in countries where cadaveric organ donation is scarc e. We undertook a successful transplantation of livingdonor islets for unstabl e diabetes. The recipient was a 27-yearold woman who had had brittle, insulin dependent diabetes mellitus for 12 years. The donor, who was a healthy 56-yea rold woman and mother of the recipient, underwent a distal pancreatectomy. Aft er isolation, 408 114 islet equivalents were transplanted immediately. The trans plants functioned immediately and the recipient became insulinindependent 22 d ays after the operation. The donor had no complications and both women showed he althy glucose tolerance. Transplantation of livingdonor islets from the distal pancreas can be sufficient to reverse brittle diabetes.
