Objective:To compare pre-and post-radical prostatectomy(RP)responses in the urinary incontinence domain of Expanded Prostate Cancer Index Composite-26(EPIC-26)in cohorts from the USA,Norway and Spain.Methods:A prospec...Objective:To compare pre-and post-radical prostatectomy(RP)responses in the urinary incontinence domain of Expanded Prostate Cancer Index Composite-26(EPIC-26)in cohorts from the USA,Norway and Spain.Methods:A prospective study of pre-and 1-year post-treatment responses in American(nZ537),Norwegian(nZ520)and Spanish(nZ111)patients,establishing the prevalence of urinary incontinence defined according to published dichotomization.Thereafter we focused on the response alternatives“occasional dribbling”,pad use and problem experience.A multivariate logistic regression analysis(significance level≤0.01)considered risk factors for“not retaining total control”.展开更多
Asthma in school-aged children is a major public health problem worldwide[1,2].Inhaled medications are the mainstay of its pharmacological management[2],but only 8%-22%of children with asthma use their inhalers correc...Asthma in school-aged children is a major public health problem worldwide[1,2].Inhaled medications are the mainstay of its pharmacological management[2],but only 8%-22%of children with asthma use their inhalers correctly[3].Asthma clinical outcomes are poor in children[4],largely due to inhaler technique[5,6].展开更多
基金The study was funded by a grant from Health-RegionSouth. East, Norway (No. 8324).
文摘Objective:To compare pre-and post-radical prostatectomy(RP)responses in the urinary incontinence domain of Expanded Prostate Cancer Index Composite-26(EPIC-26)in cohorts from the USA,Norway and Spain.Methods:A prospective study of pre-and 1-year post-treatment responses in American(nZ537),Norwegian(nZ520)and Spanish(nZ111)patients,establishing the prevalence of urinary incontinence defined according to published dichotomization.Thereafter we focused on the response alternatives“occasional dribbling”,pad use and problem experience.A multivariate logistic regression analysis(significance level≤0.01)considered risk factors for“not retaining total control”.
基金Financial support for this study was provided through Grants by the Instituto de Salud Carlos III FEDER:Fondo Europeo de Desarrollo Regional(PI15/00449)Generalitat de Catalunya(AGAUR 2021 SGR 00624,2017 SGR 452)+2 种基金The following researchers have worked on this manuscript while funded by Grants:CLB(University of Costa Rica OAICE-85-2019)KM(Instituto de Salud Carlos III FEDER:Fondo Europeo de Desarrollo Regional FI16/00071)ALD(Miguel Servet research contract from the Instituto de Salud Carlos III CP21/00062).
文摘Asthma in school-aged children is a major public health problem worldwide[1,2].Inhaled medications are the mainstay of its pharmacological management[2],but only 8%-22%of children with asthma use their inhalers correctly[3].Asthma clinical outcomes are poor in children[4],largely due to inhaler technique[5,6].