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Spatial structure of beta-amyloid Aβ_(1-40) in complex with a biological membrane model
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作者 Konstantin SUsachev Andrey VFilippov +1 位作者 oleg nantzutkin Vladimir VKlochkov 《Advances in Alzheimer's Disease》 2012年第3期22-29,共8页
The spatial structure of beta-amyloid Aβ1-40 in complex with sodium dodecyl sulfate micelles as a model membrane system was investigated by 1H-1H two-dimensional NMR (TOCSY, NOESY) spectroscopy and molecular dynamic ... The spatial structure of beta-amyloid Aβ1-40 in complex with sodium dodecyl sulfate micelles as a model membrane system was investigated by 1H-1H two-dimensional NMR (TOCSY, NOESY) spectroscopy and molecular dynamic method calculations. On the basis of NOE and chemical shifts changes data, spatial structure of the complex beta-amyloid-model of the cell surface membrane was obtained. 展开更多
关键词 1H NMR Two-Dimensional NMR (TOCSY NOESY) Spectroscopy Alzheimer’s Disease BETA-AMYLOID OLIGOPEPTIDES MICELLE
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