To compare H. pylori infection prevalence and gastric mucosa damage in HIV-in fected and non-HIV-infected patients, gastric biopsies were systematically tak en in 209 individuals who underwent upper Gl endoscopy (102H...To compare H. pylori infection prevalence and gastric mucosa damage in HIV-in fected and non-HIV-infected patients, gastric biopsies were systematically tak en in 209 individuals who underwent upper Gl endoscopy (102HIV-infected and 107 non-HIV-infected). H. pylori was fo- und in 42(41.1%)HIV-infected patients and in 53 (49.5%) non-HIV patients ( P = 0.22, χ2 =1.47, N- S). In HIV-positive patients infected with H. pylori the mean CD4 count was higher than in HIV-positive patients without H.pylori (364 and 228 cells/mm3, respectively; P = 0.0001).H. pylori gastritis was more sever e in the HI- V-positive group(χ2 = 15.02, P = 0.0001). The frequency of H. pylori in gast ric mucosa in HIV-infected and non-HIV patients was similar.HIV-infected pati ents with H. pylori had a higher mean CD4 count than HIV-infected individuals w ithout H. pylori. Gastriclesions asso- ciated with H. pylori were more severe in the HIV positive population.展开更多
文摘To compare H. pylori infection prevalence and gastric mucosa damage in HIV-in fected and non-HIV-infected patients, gastric biopsies were systematically tak en in 209 individuals who underwent upper Gl endoscopy (102HIV-infected and 107 non-HIV-infected). H. pylori was fo- und in 42(41.1%)HIV-infected patients and in 53 (49.5%) non-HIV patients ( P = 0.22, χ2 =1.47, N- S). In HIV-positive patients infected with H. pylori the mean CD4 count was higher than in HIV-positive patients without H.pylori (364 and 228 cells/mm3, respectively; P = 0.0001).H. pylori gastritis was more sever e in the HI- V-positive group(χ2 = 15.02, P = 0.0001). The frequency of H. pylori in gast ric mucosa in HIV-infected and non-HIV patients was similar.HIV-infected pati ents with H. pylori had a higher mean CD4 count than HIV-infected individuals w ithout H. pylori. Gastriclesions asso- ciated with H. pylori were more severe in the HIV positive population.