Micro fluidic chip has been applied in various biological fields owing to its low-consumption of reagents, high throughput, fuidic controllability and integrity. The well-designed microscale intermediary is also ideal...Micro fluidic chip has been applied in various biological fields owing to its low-consumption of reagents, high throughput, fuidic controllability and integrity. The well-designed microscale intermediary is also ideal for the study of cell biology. Particularly, microfluidic chip is helpful for better understanding cell-cell interactions. A general survey of recent publications would help to generalize the designs of the co-culture chips with different features. With ingenious and combinational utilization, the chips facilitate the implementation of some special coculture models that are highly concerned in a different spatial and temporal way.展开更多
文摘Micro fluidic chip has been applied in various biological fields owing to its low-consumption of reagents, high throughput, fuidic controllability and integrity. The well-designed microscale intermediary is also ideal for the study of cell biology. Particularly, microfluidic chip is helpful for better understanding cell-cell interactions. A general survey of recent publications would help to generalize the designs of the co-culture chips with different features. With ingenious and combinational utilization, the chips facilitate the implementation of some special coculture models that are highly concerned in a different spatial and temporal way.