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A pilot study using lactulose in management of minimal hepatic encephalopathy in children with extrahepatic portal vein obstruction 被引量:4
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作者 Hanaa Mostafa El-Karaksy omneya afifi +2 位作者 Azza Bakry Ann Abdel Kader Noha Saber 《World Journal of Pediatrics》 SCIE CAS CSCD 2017年第1期70-75,共6页
Background:Minimal hepatic encephalopathy(MHE)is not associated with overt neuropsychiatric symptoms but rather with subtle changes in psychometric and/or neurOphysiolOgic tests.We aimed to diagnose MHE in children wi... Background:Minimal hepatic encephalopathy(MHE)is not associated with overt neuropsychiatric symptoms but rather with subtle changes in psychometric and/or neurOphysiolOgic tests.We aimed to diagnose MHE in children with extrahepatic portal vein obstruction fEHPV01 and to evaluate the el№ct of lactulose on MHE.Methods:A prospective study was carried out on 30 patients with EHPVO(21 males;mean age 10+2.5 years).The study was carried out in the Pediatric Hepatology Unit.Cairo University Pediatric Hospital,Cairo,Egypt,between 2011 and 2013.AII patients were subjected to clinical and Iaboratory assessment.neuropsychmetric testin2 using the arabic version of Wechsler intelligence tests.neurophysiological testing by visual electroencephalogram and P300 event related potentials(ERP). 展开更多
关键词 CHILDREN EXTRAHEPATIC portal vein OBSTRUCTION LACTULOSE minimal hepatic ENCEPHALOPATHY neuropsychometric tests P300 EVENT-RELATED potential
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