The organic solvents are not only utilized in industrial processes,but also as drugs of abuse.In fact,solvent consumption represents the fourth option for drug users just after alcohol,tobacco and marijuana.In humans,...The organic solvents are not only utilized in industrial processes,but also as drugs of abuse.In fact,solvent consumption represents the fourth option for drug users just after alcohol,tobacco and marijuana.In humans,intentional inhalation of volatile drugs impairs the function of central nervous system,展开更多
The current knowledge in neuroscience indicates that the neural tissue has two major cell populations:neurons and glia(term derived from the Greek word for glue).Neuronal population is characterized by the capacity to...The current knowledge in neuroscience indicates that the neural tissue has two major cell populations:neurons and glia(term derived from the Greek word for glue).Neuronal population is characterized by the capacity to produce action potentials,whereas glial cells are typically identified as the subordinate cell population of neurons.Till date,this point of view has changed dramatically,and growing evidence indicates that glial cells play a crucial role in normal mental functions and the pathogenesis of neurological diseases.展开更多
MICROGLIA CELLS Microglia cells are antigen presenting cells with myeloid origin that constituted approximately 10%of all glial cells of the adult mouse brain.^([1])In the early embryo,the microglial precursors are lo...MICROGLIA CELLS Microglia cells are antigen presenting cells with myeloid origin that constituted approximately 10%of all glial cells of the adult mouse brain.^([1])In the early embryo,the microglial precursors are located in the yolk sac and progressively migrate throughout the primitive brain.^([2])In the adult brain,some of microglial cells derive from the bone marrow,but this process only takes place when the brain is lesioned.^([1])Microglial cells can display 4 morphological and functional stages:(1)resting microglia;(2)active microglia;(3)phagocytic microglia;and(4)senescent microglia.展开更多
基金supported by PhD CONACyT fellowship No.736339funded by CONACyT grants No.268062 and No.2015-01465
文摘The organic solvents are not only utilized in industrial processes,but also as drugs of abuse.In fact,solvent consumption represents the fourth option for drug users just after alcohol,tobacco and marijuana.In humans,intentional inhalation of volatile drugs impairs the function of central nervous system,
基金The National Institute of Health and the National Institute of Neurological Disorders and Stroke(NIH/NINDS,R01-NS070024)Consejo Nacional de Ciencia y Tecnologia(CONACyT,INFR2014-224359)Programa de Desarrollo del Personal Docente(PRODEP-Redes 2014).
文摘The current knowledge in neuroscience indicates that the neural tissue has two major cell populations:neurons and glia(term derived from the Greek word for glue).Neuronal population is characterized by the capacity to produce action potentials,whereas glial cells are typically identified as the subordinate cell population of neurons.Till date,this point of view has changed dramatically,and growing evidence indicates that glial cells play a crucial role in normal mental functions and the pathogenesis of neurological diseases.
基金financed by grants from Consejo Nacional de Ciencia y Tecnología(CONACyT-2015-01-465)ELD by CONACyT’s Fellowhip grant(No.736004).
文摘MICROGLIA CELLS Microglia cells are antigen presenting cells with myeloid origin that constituted approximately 10%of all glial cells of the adult mouse brain.^([1])In the early embryo,the microglial precursors are located in the yolk sac and progressively migrate throughout the primitive brain.^([2])In the adult brain,some of microglial cells derive from the bone marrow,but this process only takes place when the brain is lesioned.^([1])Microglial cells can display 4 morphological and functional stages:(1)resting microglia;(2)active microglia;(3)phagocytic microglia;and(4)senescent microglia.
