Background Very elderly patients represent a distinct patient group in clinical setting in terms of a decision for trans-catheter aortic valve replacement （TAVR） when one considers the potential improvement in the q...Background Very elderly patients represent a distinct patient group in clinical setting in terms of a decision for trans-catheter aortic valve replacement （TAVR） when one considers the potential improvement in the quality of life （QoL） on one hand and the benefit to risk ratio on the other. This study aimed to compare functional and QoL outcomes of TAVR between octogenarians and septuagenarians. Methods This prospective cohort study included 136 elderly patients （70 to 89 years of age）, who tmderwent Wansfemoral TAVR due to degenerative aortic stenosis. Patients were allocated into one of the following age groups： septuagenarians （n = 67） and octogenarians （n = 69）. Preoperative and early postoperative clinical parameteT：s were recorded. In addition, QoL of the patients was evaluated using SF-36 questionnaire preoperatively and six month postoperatively. Results Groups were similar in terms of early postoperative mortality and morbidity parameters. The mean New York Heart Association （NYHA） class improved after TAVR in both groups. In addition, all SF-36 norm-based scale and SF-36 summary scale scores improved significantly in both groups during the postoperative period. Postoperatively, physical functioning, general health and physical component summary scores were significantly better in the septuagenarian group （P = 0.02, 0.01, 0.03, respectively）. ConcLusion Although the improvement in the QoL in terms of physical health was more marked in septuagenarians than in octogenarians, substantial benefits on the QoL and particularly on mental health seem to justify re-consideration of TAVR indications in the very elderly.展开更多
This study has been investigated some pipeline lines after collapsing process of Union of Soviet Socialist Republics from Azerbaijan to Europe and another alternative ways from Russia. As we know Russia is a big power...This study has been investigated some pipeline lines after collapsing process of Union of Soviet Socialist Republics from Azerbaijan to Europe and another alternative ways from Russia. As we know Russia is a big power as from economic, defensive, and political aspects, as that＇s in ruler position in the region. So, USA from another side of the world as a super power of the world could make dimension of those pipelines from transit of Turkey. That＇s why new Nabucco project has been also cancelled by Russia＇s power. This article has been studied newly established project of Trans Anatolian Natural Gas Line Project （TANAP） from Azerbaijan＇s oil and gas department; Ministry＇s State Petroleum Company＇s （SOCAR） project has not been cancelled by Turkish Petroleum Company （TPAO）. So TANAP＇s advantages and disadvantages have been researched in this article.展开更多
文摘Background Very elderly patients represent a distinct patient group in clinical setting in terms of a decision for trans-catheter aortic valve replacement （TAVR） when one considers the potential improvement in the quality of life （QoL） on one hand and the benefit to risk ratio on the other. This study aimed to compare functional and QoL outcomes of TAVR between octogenarians and septuagenarians. Methods This prospective cohort study included 136 elderly patients （70 to 89 years of age）, who tmderwent Wansfemoral TAVR due to degenerative aortic stenosis. Patients were allocated into one of the following age groups： septuagenarians （n = 67） and octogenarians （n = 69）. Preoperative and early postoperative clinical parameteT：s were recorded. In addition, QoL of the patients was evaluated using SF-36 questionnaire preoperatively and six month postoperatively. Results Groups were similar in terms of early postoperative mortality and morbidity parameters. The mean New York Heart Association （NYHA） class improved after TAVR in both groups. In addition, all SF-36 norm-based scale and SF-36 summary scale scores improved significantly in both groups during the postoperative period. Postoperatively, physical functioning, general health and physical component summary scores were significantly better in the septuagenarian group （P = 0.02, 0.01, 0.03, respectively）. ConcLusion Although the improvement in the QoL in terms of physical health was more marked in septuagenarians than in octogenarians, substantial benefits on the QoL and particularly on mental health seem to justify re-consideration of TAVR indications in the very elderly.
文摘This study has been investigated some pipeline lines after collapsing process of Union of Soviet Socialist Republics from Azerbaijan to Europe and another alternative ways from Russia. As we know Russia is a big power as from economic, defensive, and political aspects, as that＇s in ruler position in the region. So, USA from another side of the world as a super power of the world could make dimension of those pipelines from transit of Turkey. That＇s why new Nabucco project has been also cancelled by Russia＇s power. This article has been studied newly established project of Trans Anatolian Natural Gas Line Project （TANAP） from Azerbaijan＇s oil and gas department; Ministry＇s State Petroleum Company＇s （SOCAR） project has not been cancelled by Turkish Petroleum Company （TPAO）. So TANAP＇s advantages and disadvantages have been researched in this article.
