<div style="text-align:justify;"> <strong><span style="font-family:Verdana;">Background:</span></strong><span style="font-family:Verdana;"> Intensity M...<div style="text-align:justify;"> <strong><span style="font-family:Verdana;">Background:</span></strong><span style="font-family:Verdana;"> Intensity Modulated Radiation Therapy (IMRT) is currently employed as a major arm of treatment in multiforme glioblastoma (GBM). The present study aimed to compare 3D-CRT with IMRT to assess tumor volume coverage and OAR sparing for </span><span style="font-family:Verdana;">the </span><span "=""><span style="font-family:Verdana;">treatment of malignant gliomas. </span><b><span style="font-family:Verdana;">Materials</span></b> <b><span style="font-family:Verdana;">and</span></b> <b><span style="font-family:Verdana;">methods:</span></b><span style="font-family:Verdana;"> We assessed 22 anonymized patients datasets with High Grade Glioblastoma who had undergone post</span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">operative Intensity Modulated Radiotherapy (IMRT) and 3D Conformal Radiotherapy (3D-CRT), This study will compare and contrast treatment plans Rapidarc and 3D-CRT to determine w</span><span style="font-family:Verdana;">h</span><span style="font-family:Verdana;">ich techn</span><span style="font-family:Verdana;">ology</span><span "=""><span style="font-family:Verdana;"> improves significantly dosimetric parameters. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Plans will be assessed by reviewing the coverage of the PTV using mean, maximum and minimum doses while the OAR doses will be compared using the maximal doses for each, as set out in the QUANTEC dose limits. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The use of IMRT seems a superior technique as compared to 3D-CRT for the treatment of malignant gliomas having the potential to increase </span></span><span style="font-family:Verdana;">the </span><span style="font-family:Verdana;">dose to the PTV while sparing OARs optimally.</span> </div>展开更多
文摘<div style="text-align:justify;"> <strong><span style="font-family:Verdana;">Background:</span></strong><span style="font-family:Verdana;"> Intensity Modulated Radiation Therapy (IMRT) is currently employed as a major arm of treatment in multiforme glioblastoma (GBM). The present study aimed to compare 3D-CRT with IMRT to assess tumor volume coverage and OAR sparing for </span><span style="font-family:Verdana;">the </span><span "=""><span style="font-family:Verdana;">treatment of malignant gliomas. </span><b><span style="font-family:Verdana;">Materials</span></b> <b><span style="font-family:Verdana;">and</span></b> <b><span style="font-family:Verdana;">methods:</span></b><span style="font-family:Verdana;"> We assessed 22 anonymized patients datasets with High Grade Glioblastoma who had undergone post</span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">operative Intensity Modulated Radiotherapy (IMRT) and 3D Conformal Radiotherapy (3D-CRT), This study will compare and contrast treatment plans Rapidarc and 3D-CRT to determine w</span><span style="font-family:Verdana;">h</span><span style="font-family:Verdana;">ich techn</span><span style="font-family:Verdana;">ology</span><span "=""><span style="font-family:Verdana;"> improves significantly dosimetric parameters. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Plans will be assessed by reviewing the coverage of the PTV using mean, maximum and minimum doses while the OAR doses will be compared using the maximal doses for each, as set out in the QUANTEC dose limits. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The use of IMRT seems a superior technique as compared to 3D-CRT for the treatment of malignant gliomas having the potential to increase </span></span><span style="font-family:Verdana;">the </span><span style="font-family:Verdana;">dose to the PTV while sparing OARs optimally.</span> </div>