The widespread outbreak of SARS-CoV-2 was declared a public health emergency by the World Health Organization and various governments worldwide.This prompted the implementation of stringent infection control measures ...The widespread outbreak of SARS-CoV-2 was declared a public health emergency by the World Health Organization and various governments worldwide.This prompted the implementation of stringent infection control measures to curb the spread of the virus.Amidst this,the medical community faced the challenge of treating the virus without specific therapies or a vaccine,leading to reliance on empirical treatment approaches.In this context,hydroxychloroquine,an antimalarial and antirheumatic drug,gained attention as a potential treatment option.Despite its theoretical benefits,such as inhibiting viral entry,reducing inflammation,and modulating immune responses,empirical studies yielded inconsistent results.Some indicated a potential for symptom relief,while others showed no significant improvement in patient outcomes.The initial enthusiasm waned as the lack of substantial evidence led to revoking its Emergency Use Authorization,and several clinical trials were prematurely halted.The review in question critically examines the factors contributing to the ineffectiveness of hydroxychloroquine in treating SARS-CoV-2 infection,highlighting the complexities of drug repurposing during a rapidly evolving pandemic.展开更多
Objective:To assess the preparedness for handling injuries by female primary school teachers based on their knowledge,attitude,practice and their willingness to learn first aid.Methods:A cross-sectional questionnaire ...Objective:To assess the preparedness for handling injuries by female primary school teachers based on their knowledge,attitude,practice and their willingness to learn first aid.Methods:A cross-sectional questionnaire on first aid was provided to female primary school teachers,and the knowledge,attitude,practice and their willingness to learn first aid were investigated.Data were analyzed using SPSS version 23.Quantitative data were analyzed by one-way ANOVA,categorical variables were analyzed by the Chi-square test.The level of significance was set at P<0.05.Results:In total,464 teachers of different age groups and education responded.The mean knowledge score was low but the mean attitude score was high.Parental consent was sought by one-fourth of the teachers,and 25.6%of teachers documented the health status of children.Most of the teachers desired to have a first aider,and they were keen on training(62.3%)and educating children(88.1%)on first aid.Knowledge scores were significantly impacted by age(P<0.05)and experience(P<0.01),while specialization impacted mean practice scores(P<0.001).Teachers'qualification(P<0.05),first action to be taken at the accident site(P<0.05),and frequency of training(P<0.05),were significantly associated with the need of a first aider.Conclusions:Based on the paucity of awareness and expertise,on priority basis,it is important to strengthen teachers'skills.Child safety is an important public health issue and can be improved by educating and training teachers.展开更多
文摘The widespread outbreak of SARS-CoV-2 was declared a public health emergency by the World Health Organization and various governments worldwide.This prompted the implementation of stringent infection control measures to curb the spread of the virus.Amidst this,the medical community faced the challenge of treating the virus without specific therapies or a vaccine,leading to reliance on empirical treatment approaches.In this context,hydroxychloroquine,an antimalarial and antirheumatic drug,gained attention as a potential treatment option.Despite its theoretical benefits,such as inhibiting viral entry,reducing inflammation,and modulating immune responses,empirical studies yielded inconsistent results.Some indicated a potential for symptom relief,while others showed no significant improvement in patient outcomes.The initial enthusiasm waned as the lack of substantial evidence led to revoking its Emergency Use Authorization,and several clinical trials were prematurely halted.The review in question critically examines the factors contributing to the ineffectiveness of hydroxychloroquine in treating SARS-CoV-2 infection,highlighting the complexities of drug repurposing during a rapidly evolving pandemic.
文摘Objective:To assess the preparedness for handling injuries by female primary school teachers based on their knowledge,attitude,practice and their willingness to learn first aid.Methods:A cross-sectional questionnaire on first aid was provided to female primary school teachers,and the knowledge,attitude,practice and their willingness to learn first aid were investigated.Data were analyzed using SPSS version 23.Quantitative data were analyzed by one-way ANOVA,categorical variables were analyzed by the Chi-square test.The level of significance was set at P<0.05.Results:In total,464 teachers of different age groups and education responded.The mean knowledge score was low but the mean attitude score was high.Parental consent was sought by one-fourth of the teachers,and 25.6%of teachers documented the health status of children.Most of the teachers desired to have a first aider,and they were keen on training(62.3%)and educating children(88.1%)on first aid.Knowledge scores were significantly impacted by age(P<0.05)and experience(P<0.01),while specialization impacted mean practice scores(P<0.001).Teachers'qualification(P<0.05),first action to be taken at the accident site(P<0.05),and frequency of training(P<0.05),were significantly associated with the need of a first aider.Conclusions:Based on the paucity of awareness and expertise,on priority basis,it is important to strengthen teachers'skills.Child safety is an important public health issue and can be improved by educating and training teachers.
