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非动脉性前部缺血性视神经病变与勃起功能障碍的治疗
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作者 McGwin Jr. G Vaphiades M. S +2 位作者 Hall T. A owsleyc 王静波(译) 《世界核心医学期刊文摘(眼科学分册)》 2006年第5期19-20,共2页
Aim: To determine the association between Viagra (sildenafil)-and Cialis (tadalafil) and non-arteritic anterior ischaemic optic neuropathy (NAION).Methods: A retrospective matched case control study was conducted. 38 ... Aim: To determine the association between Viagra (sildenafil)-and Cialis (tadalafil) and non-arteritic anterior ischaemic optic neuropathy (NAION).Methods: A retrospective matched case control study was conducted. 38 cases of NAION in males were identified from an academic ophthalmology practice in Birmingham, Alabama, and matched (on age) to 38 controls without a history of NAION. Self reported information regarding past and current use of Viagra and/or Cialis was obtained via a telephone questionnaire from interviewers who were not blind to case status. Results: Overall, males with NAION were no more likely to report a history of Viagra or Cialis use compared to similarly aged controls (odd ratio (OR) 1.75, 95%confidence interval (CI) 0.48 to 6.30 and OR 1.82, 95%CI 0.21 to 15.39). However, for those with a history of myocardial infarction, a statistically significant association was observed (OR 10.7, 95%CI 1.3 to 95.8). A similar association was observed for those with a history of hypertension though it lacked statistical significance (OR 6.9, 95%CI 0.8 to 63.6). Conclusions: For men with a history of myocardial infarction or hypertension the use of Viagra or Cialis may increase the risk of NAION. Physicians prescribing these medications to patients with these conditions should warn them about the potential risk ofNAION. 展开更多
关键词 前部缺血性视神经病变 勃起功能障碍 动脉性 病例对照研究 NAION 治疗 男性患者 眼科诊所 自我报告 电话调查
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