New Zealand (NZ) young rabbits with the administration of insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) with and without mandibular anterior repositioning appliances are explored for th...New Zealand (NZ) young rabbits with the administration of insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) with and without mandibular anterior repositioning appliances are explored for the growth of the mandibular condylar cartilage (MCC). 32 growing NZ and rabbits were divided into 4 groups: the group with saline injection in TMJ, the group which received growth factor injection in TMJ, the group which received anterior positioning appliance and the group which received growth factors injection as well as mandibular repositioning appliance. Gene expression was studied by real-time RT-PCR and cartilage growth by histomorphometry. Administration of growth factors along with mandibular repositioning appliances has induced 1) 1.70-fold expression of Col-2Agene (p value < 0.0005) and 2) 1.47-fold expression of Col-10Agene (p value < 0.0005). In contrast, administration of only mandibular repositioning appliances induced 1) 1.28-fold expression of Col-2Agene (p value < 0.0005) and 2) merely 0.62-fold expression of Col-10Agene (p value < 0.0005), while administration of growth factors only induced 1) mere 0.56-fold expression of Col-2Agene (p value 10A gene (p value growth factors along with mandibular repositioning appliances causes an increase in genetic expressions which have been corroborated by histomorphometry and validated by statistical analysis, during an accelerated growth of mandibular condylar cartilage. Administration of growth factors in the TMJ could provide a synergistic role along with mandibular repositioning appliances for treatment of mandibular retrognathism as well as disorders on the MCC.展开更多
The objective of this research was to study the mode of inheritance of resistance to mungbean yellow mosaic virus (MYMV) in inter TNAU RED × VRM (Gg) 1 and intra KMG 189 × VBN (Gg) 2 specific crosses of mung...The objective of this research was to study the mode of inheritance of resistance to mungbean yellow mosaic virus (MYMV) in inter TNAU RED × VRM (Gg) 1 and intra KMG 189 × VBN (Gg) 2 specific crosses of mungbean. An infector row technique was used for evaluating parents, F1, F2 and F3 plants for MYMV resistance. No insecticide was sprayed in order to maintain the natural whitefly population in experimental field. In the field condition, only after 80% of plants showed MYMV incidence, and the scoring of the test materials was done by MYMV disease rating scale. According to the mean disease score, the mungbean genotypes were categorized into five groups resistant (R), moderately resistant (MR), moderately susceptible (MS), susceptible (S) and highly susceptible (HS). 3 (Susceptible): 1 (Resistance) was observed in all two crosses of all F2 population and it showed that the dominance of susceptibility over the resistance and the results of the F3 segregation (1:2:1) confirm the segregation pattern of the F2 segregation. Collectively all the two crosses F2 and F3 generations results suggested that a single recessive gene is involved in resistance against the MYMV disease.展开更多
文摘New Zealand (NZ) young rabbits with the administration of insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) with and without mandibular anterior repositioning appliances are explored for the growth of the mandibular condylar cartilage (MCC). 32 growing NZ and rabbits were divided into 4 groups: the group with saline injection in TMJ, the group which received growth factor injection in TMJ, the group which received anterior positioning appliance and the group which received growth factors injection as well as mandibular repositioning appliance. Gene expression was studied by real-time RT-PCR and cartilage growth by histomorphometry. Administration of growth factors along with mandibular repositioning appliances has induced 1) 1.70-fold expression of Col-2Agene (p value < 0.0005) and 2) 1.47-fold expression of Col-10Agene (p value < 0.0005). In contrast, administration of only mandibular repositioning appliances induced 1) 1.28-fold expression of Col-2Agene (p value < 0.0005) and 2) merely 0.62-fold expression of Col-10Agene (p value < 0.0005), while administration of growth factors only induced 1) mere 0.56-fold expression of Col-2Agene (p value 10A gene (p value growth factors along with mandibular repositioning appliances causes an increase in genetic expressions which have been corroborated by histomorphometry and validated by statistical analysis, during an accelerated growth of mandibular condylar cartilage. Administration of growth factors in the TMJ could provide a synergistic role along with mandibular repositioning appliances for treatment of mandibular retrognathism as well as disorders on the MCC.
文摘The objective of this research was to study the mode of inheritance of resistance to mungbean yellow mosaic virus (MYMV) in inter TNAU RED × VRM (Gg) 1 and intra KMG 189 × VBN (Gg) 2 specific crosses of mungbean. An infector row technique was used for evaluating parents, F1, F2 and F3 plants for MYMV resistance. No insecticide was sprayed in order to maintain the natural whitefly population in experimental field. In the field condition, only after 80% of plants showed MYMV incidence, and the scoring of the test materials was done by MYMV disease rating scale. According to the mean disease score, the mungbean genotypes were categorized into five groups resistant (R), moderately resistant (MR), moderately susceptible (MS), susceptible (S) and highly susceptible (HS). 3 (Susceptible): 1 (Resistance) was observed in all two crosses of all F2 population and it showed that the dominance of susceptibility over the resistance and the results of the F3 segregation (1:2:1) confirm the segregation pattern of the F2 segregation. Collectively all the two crosses F2 and F3 generations results suggested that a single recessive gene is involved in resistance against the MYMV disease.
