Objective The purpose of this study was to determine the serum uric acid levels and the prevalence of hyperuricemia among Chinese adults in 2015 and compare the differences between urban and rural areas,as well as the...Objective The purpose of this study was to determine the serum uric acid levels and the prevalence of hyperuricemia among Chinese adults in 2015 and compare the differences between urban and rural areas,as well as the differences between eastern,central,and western regions.Methods A national representative sample of 180,208 participants were included using a stratified,multistage,and random sampling method.The demographic characteristics and blood samples were collected to determine the serum uric acid levels and prevalence of hyperuricemia among subgroups using complicated sampling weight.A t-test or ANOVA was used for normally-distributed data.The Kruskal-Wallis rank test was used for skewed-distributed data.The Mantel-Haenszel chi-square test was used to compare the difference in categorical variables.Results The weighted mean uric acid level in Chinese adults was 310.4μmol/L(317.5μmol/L in urban areas and 302.9μmol/L in rural areas).The weighted average values of uric acid in eastern,central,and western China were 315.5μmol/L,303.5μmol/L,and 310.4μmol/L,respectively.The weighted prevalence of hyperuricemia in Chinese adults was 14.6%,with a prevalence of 16.5%in urban areas and12.5%in rural areas.The weighted prevalence of hyperuricemia in eastern,central,and western China was 16.0%,12.5%,and 14.8%,respectively.Conclusion The uric acid level in Chinese adults is relatively high.Effective actions are warranted to improve this metabolic abnormality.展开更多
Nontuberculous mycobacteria(NTM)are opportunistic pathogens of environmental origin that can cause human infections in a wide variety of tissues[1].Lung involvement is the most common manifestation of NTM infection[1]...Nontuberculous mycobacteria(NTM)are opportunistic pathogens of environmental origin that can cause human infections in a wide variety of tissues[1].Lung involvement is the most common manifestation of NTM infection[1].The symptoms and radiographic signs are similar to those of patients with pulmonary tuberculosis(TB)who are infected with Mycobacterium tuberculosis complex(MTBC)[1].Most NTM species are naturally resistant to first-line anti-TB drugs and have different resistance profiles,thus misdiagnosis leads to inappropriate treatment and increases the risk of poor prognosis for patients with an NTM infection,and even wider spread through person-to-person contact[2].展开更多
基金supported by the Chinese Adults Chronic Diseases and Nutrition Surveillance(2015)
文摘Objective The purpose of this study was to determine the serum uric acid levels and the prevalence of hyperuricemia among Chinese adults in 2015 and compare the differences between urban and rural areas,as well as the differences between eastern,central,and western regions.Methods A national representative sample of 180,208 participants were included using a stratified,multistage,and random sampling method.The demographic characteristics and blood samples were collected to determine the serum uric acid levels and prevalence of hyperuricemia among subgroups using complicated sampling weight.A t-test or ANOVA was used for normally-distributed data.The Kruskal-Wallis rank test was used for skewed-distributed data.The Mantel-Haenszel chi-square test was used to compare the difference in categorical variables.Results The weighted mean uric acid level in Chinese adults was 310.4μmol/L(317.5μmol/L in urban areas and 302.9μmol/L in rural areas).The weighted average values of uric acid in eastern,central,and western China were 315.5μmol/L,303.5μmol/L,and 310.4μmol/L,respectively.The weighted prevalence of hyperuricemia in Chinese adults was 14.6%,with a prevalence of 16.5%in urban areas and12.5%in rural areas.The weighted prevalence of hyperuricemia in eastern,central,and western China was 16.0%,12.5%,and 14.8%,respectively.Conclusion The uric acid level in Chinese adults is relatively high.Effective actions are warranted to improve this metabolic abnormality.
基金funded in part by the Sanming Project of Medicine in Shenzhen[SZSM201611030]the Fundamental Research Funds for the Central Universities[2042021kf0041]Guangdong Medical Science and Technology Research Fund[B2021075].
文摘Nontuberculous mycobacteria(NTM)are opportunistic pathogens of environmental origin that can cause human infections in a wide variety of tissues[1].Lung involvement is the most common manifestation of NTM infection[1].The symptoms and radiographic signs are similar to those of patients with pulmonary tuberculosis(TB)who are infected with Mycobacterium tuberculosis complex(MTBC)[1].Most NTM species are naturally resistant to first-line anti-TB drugs and have different resistance profiles,thus misdiagnosis leads to inappropriate treatment and increases the risk of poor prognosis for patients with an NTM infection,and even wider spread through person-to-person contact[2].